Fig 1: Enrichment plot: CHR5Q13
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | CHR5Q13 |
| Enrichment Score (ES) | 0.4437171 |
| Normalized Enrichment Score (NES) | 1.1329733 |
| Nominal p-value | 0.14084508 |
| FDR q-value | 0.69158316 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SUMO2P5 | SUMO2 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:39015] | 149 | 4.190 | 0.0601 | Yes |
| 2 | MAP1B | microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] | 180 | 4.023 | 0.1208 | Yes |
| 3 | TMEM171 | transmembrane protein 171 [Source:HGNC Symbol;Acc:HGNC:27031] | 231 | 3.800 | 0.1776 | Yes |
| 4 | HMGN2P4 | high mobility group nucleosomal binding domain 2 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:33567] | 297 | 3.497 | 0.2294 | Yes |
| 5 | SUMO2P4 | SUMO2 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:39014] | 405 | 3.199 | 0.2754 | Yes |
| 6 | ALDH7A1P1 | aldehyde dehydrogenase 7 family member A1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:878] | 747 | 2.548 | 0.3052 | Yes |
| 7 | AGGF1 | angiogenic factor with G-patch and FHA domains 1 [Source:HGNC Symbol;Acc:HGNC:24684] | 1158 | 1.999 | 0.3247 | Yes |
| 8 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 2154 | 1.371 | 0.3188 | Yes |
| 9 | CFL1P5 | cofilin 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:1877] | 2164 | 1.365 | 0.3394 | Yes |
| 10 | CDK7 | cyclin dependent kinase 7 [Source:HGNC Symbol;Acc:HGNC:1778] | 2595 | 1.115 | 0.3449 | Yes |
| 11 | IQGAP2 | IQ motif containing GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:6111] | 2597 | 1.114 | 0.3619 | Yes |
| 12 | GTF2H2B | general transcription factor IIH subunit 2B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:31393] | 2703 | 1.062 | 0.3753 | Yes |
| 13 | SAP18P1 | SAP18 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:51567] | 2714 | 1.062 | 0.3913 | Yes |
| 14 | CCDC125 | coiled-coil domain containing 125 [Source:HGNC Symbol;Acc:HGNC:28924] | 2752 | 1.046 | 0.4063 | Yes |
| 15 | AK6 | adenylate kinase 6 [Source:HGNC Symbol;Acc:HGNC:49151] | 2891 | 0.980 | 0.4175 | Yes |
| 16 | BIN2P2 | bridging integrator 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:43661] | 3053 | 0.921 | 0.4273 | Yes |
| 17 | SNRPCP2 | small nuclear ribonucleoprotein polypeptide C pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:49817] | 3175 | 0.879 | 0.4374 | Yes |
| 18 | UTP15 | UTP15 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:25758] | 3834 | 0.665 | 0.4298 | Yes |
| 19 | MRPS27 | mitochondrial ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:14512] | 3933 | 0.631 | 0.4368 | Yes |
| 20 | NDUFB9P1 | NADH:ubiquinone oxidoreductase subunit B9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:52269] | 4076 | 0.584 | 0.4419 | Yes |
| 21 | RPL7P23 | ribosomal protein L7 pseudogene 23 [Source:HGNC Symbol;Acc:HGNC:35658] | 4304 | 0.519 | 0.4437 | Yes |
| 22 | NAIP | NLR family apoptosis inhibitory protein [Source:HGNC Symbol;Acc:HGNC:7634] | 4803 | 0.393 | 0.4363 | No |
| 23 | BTF3 | basic transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:1125] | 5096 | 0.311 | 0.4331 | No |
| 24 | TAF9 | TATA-box binding protein associated factor 9 [Source:HGNC Symbol;Acc:HGNC:11542] | 5513 | 0.215 | 0.4252 | No |
| 25 | RAD17 | RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807] | 5866 | 0.130 | 0.4176 | No |
| 26 | VWA8P1 | von Willebrand factor A domain containing 8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44271] | 6523 | 0.000 | 0.3999 | No |
| 27 | LINC01385 | long intergenic non-protein coding RNA 1385 [Source:HGNC Symbol;Acc:HGNC:50657] | 6917 | 0.000 | 0.3892 | No |
| 28 | LINC01386 | long intergenic non-protein coding RNA 1386 [Source:HGNC Symbol;Acc:HGNC:50659] | 6918 | 0.000 | 0.3892 | No |
| 29 | LINC01333 | long intergenic non-protein coding RNA 1333 [Source:HGNC Symbol;Acc:HGNC:50539] | 7071 | 0.000 | 0.3851 | No |
| 30 | LINC01335 | long intergenic non-protein coding RNA 1335 [Source:HGNC Symbol;Acc:HGNC:50542] | 7072 | 0.000 | 0.3851 | No |
| 31 | LINC01331 | long intergenic non-protein coding RNA 1331 [Source:HGNC Symbol;Acc:HGNC:50538] | 7106 | 0.000 | 0.3842 | No |
| 32 | LINC01332 | long intergenic non-protein coding RNA 1332 [Source:HGNC Symbol;Acc:HGNC:50540] | 7107 | 0.000 | 0.3842 | No |
| 33 | ANKRD31 | ankyrin repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:26853] | 7762 | 0.000 | 0.3666 | No |
| 34 | PMCHL2 | pro-melanin concentrating hormone like 2 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:9111] | 8989 | 0.000 | 0.3334 | No |
| 35 | CRHBP | corticotropin releasing hormone binding protein [Source:HGNC Symbol;Acc:HGNC:2356] | 9686 | 0.000 | 0.3146 | No |
| 36 | GTF2H2C | GTF2H2 family member C [Source:HGNC Symbol;Acc:HGNC:31394] | 9726 | 0.000 | 0.3135 | No |
| 37 | S100Z | S100 calcium binding protein Z [Source:HGNC Symbol;Acc:HGNC:30367] | 11759 | 0.000 | 0.2585 | No |
| 38 | ZBED3-AS1 | ZBED3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44188] | 11880 | 0.000 | 0.2553 | No |
| 39 | RNU6-1330P | RNA, U6 small nuclear 1330, pseudogene [Source:HGNC Symbol;Acc:HGNC:48293] | 11984 | 0.000 | 0.2525 | No |
| 40 | RNU7-196P | RNA, U7 small nuclear 196 pseudogene [Source:HGNC Symbol;Acc:HGNC:45730] | 12207 | 0.000 | 0.2465 | No |
| 41 | SLC25A5P9 | solute carrier family 25 member 5 pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:35468] | 12553 | 0.000 | 0.2372 | No |
| 42 | CARTPT | CART prepropeptide [Source:HGNC Symbol;Acc:HGNC:24323] | 12573 | 0.000 | 0.2367 | No |
| 43 | TMEM174 | transmembrane protein 174 [Source:HGNC Symbol;Acc:HGNC:28187] | 13268 | 0.000 | 0.2179 | No |
| 44 | RN7SL814P | RNA, 7SL, cytoplasmic 814, pseudogene [Source:HGNC Symbol;Acc:HGNC:46830] | 13363 | 0.000 | 0.2154 | No |
| 45 | LINC02242 | long intergenic non-protein coding RNA 2242 [Source:HGNC Symbol;Acc:HGNC:53127] | 13838 | 0.000 | 0.2025 | No |
| 46 | LINC02230 | long intergenic non-protein coding RNA 2230 [Source:HGNC Symbol;Acc:HGNC:53099] | 13859 | 0.000 | 0.2020 | No |
| 47 | LINC02219 | long intergenic non-protein coding RNA 2219 [Source:HGNC Symbol;Acc:HGNC:53086] | 14133 | 0.000 | 0.1946 | No |
| 48 | LINC02122 | long intergenic non-protein coding RNA 2122 [Source:HGNC Symbol;Acc:HGNC:52979] | 14303 | 0.000 | 0.1900 | No |
| 49 | LINC02198 | long intergenic non-protein coding RNA 2198 [Source:HGNC Symbol;Acc:HGNC:53064] | 14429 | 0.000 | 0.1867 | No |
| 50 | LINC02197 | long intergenic non-protein coding RNA 2197 [Source:HGNC Symbol;Acc:HGNC:53063] | 14434 | 0.000 | 0.1865 | No |
| 51 | RNU6-658P | RNA, U6 small nuclear 658, pseudogene [Source:HGNC Symbol;Acc:HGNC:47621] | 16014 | 0.000 | 0.1438 | No |
| 52 | SNORA47 | small nucleolar RNA, H/ACA box 47 [Source:HGNC Symbol;Acc:HGNC:32640] | 16129 | 0.000 | 0.1408 | No |
| 53 | AC026725.1 | novel transcript | 16306 | 0.000 | 0.1360 | No |
| 54 | F2R | coagulation factor II thrombin receptor [Source:HGNC Symbol;Acc:HGNC:3537] | 16498 | 0.000 | 0.1308 | No |
| 55 | RNU6-680P | RNA, U6 small nuclear 680, pseudogene [Source:HGNC Symbol;Acc:HGNC:47643] | 16540 | 0.000 | 0.1297 | No |
| 56 | RNU6ATAC36P | RNA, U6atac small nuclear 36, pseudogene [Source:HGNC Symbol;Acc:HGNC:46935] | 17748 | 0.000 | 0.0971 | No |
| 57 | GTF2H2 | general transcription factor IIH subunit 2 [Source:HGNC Symbol;Acc:HGNC:4656] | 17863 | 0.000 | 0.0940 | No |
| 58 | BCL9P1 | BCL9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:51328] | 18022 | 0.000 | 0.0897 | No |
| 59 | RNA5SP186 | RNA, 5S ribosomal pseudogene 186 [Source:HGNC Symbol;Acc:HGNC:43086] | 18862 | 0.000 | 0.0670 | No |
| 60 | ANKDD1B | ankyrin repeat and death domain containing 1B [Source:HGNC Symbol;Acc:HGNC:32525] | 19069 | 0.000 | 0.0614 | No |
| 61 | GCNT4 | glucosaminyl (N-acetyl) transferase 4 [Source:HGNC Symbol;Acc:HGNC:17973] | 19304 | 0.000 | 0.0551 | No |
| 62 | RN7SL153P | RNA, 7SL, cytoplasmic 153, pseudogene [Source:HGNC Symbol;Acc:HGNC:46169] | 19337 | 0.000 | 0.0543 | No |
| 63 | FOXD1-AS1 | FOXD1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50658] | 19750 | 0.000 | 0.0431 | No |
| 64 | RPL7P22 | ribosomal protein L7 pseudogene 22 [Source:HGNC Symbol;Acc:HGNC:35802] | 20434 | 0.000 | 0.0246 | No |
| 65 | FOXD1 | forkhead box D1 [Source:HGNC Symbol;Acc:HGNC:3802] | 20753 | 0.000 | 0.0160 | No |
| 66 | AC116345.3 | novel transcript | 21280 | 0.000 | 0.0018 | No |
| 67 | RN7SL208P | RNA, 7SL, cytoplasmic 208, pseudogene [Source:HGNC Symbol;Acc:HGNC:46224] | 21458 | 0.000 | -0.0030 | No |
| 68 | FAM169A | family with sequence similarity 169 member A [Source:HGNC Symbol;Acc:HGNC:29138] | 21992 | 0.000 | -0.0174 | No |
| 69 | HMGN1P12 | high mobility group nucleosome binding domain 1 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:39356] | 22137 | 0.000 | -0.0213 | No |
| 70 | YBX1P5 | Y-box binding protein 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:42426] | 22256 | 0.000 | -0.0245 | No |
| 71 | RNU7-175P | RNA, U7 small nuclear 175 pseudogene [Source:HGNC Symbol;Acc:HGNC:45709] | 22317 | 0.000 | -0.0261 | No |
| 72 | GUSBP9 | GUSB pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:42323] | 22588 | 0.000 | -0.0334 | No |
| 73 | GUSBP3 | GUSB pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:37301] | 22589 | 0.000 | -0.0334 | No |
| 74 | CDH12P1 | cadherin 12 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:37698] | 22644 | 0.000 | -0.0349 | No |
| 75 | CDH12P2 | cadherin 12 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:1752] | 22646 | 0.000 | -0.0349 | No |
| 76 | CDH12P3 | cadherin 12 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:37699] | 22647 | 0.000 | -0.0349 | No |
| 77 | CDH12P4 | cadherin 12 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:37700] | 22648 | 0.000 | -0.0349 | No |
| 78 | SMN2 | survival of motor neuron 2, centromeric [Source:HGNC Symbol;Acc:HGNC:11118] | 22756 | 0.000 | -0.0378 | No |
| 79 | RNU6-1232P | RNA, U6 small nuclear 1232, pseudogene [Source:HGNC Symbol;Acc:HGNC:48195] | 23201 | 0.000 | -0.0498 | No |
| 80 | ARHGEF28 | Rho guanine nucleotide exchange factor 28 [Source:HGNC Symbol;Acc:HGNC:30322] | 23276 | 0.000 | -0.0518 | No |
| 81 | OCLN | occludin [Source:HGNC Symbol;Acc:HGNC:8104] | 23510 | 0.000 | -0.0581 | No |
| 82 | MIR4803 | microRNA 4803 [Source:HGNC Symbol;Acc:HGNC:41568] | 23726 | 0.000 | -0.0639 | No |
| 83 | MIR4804 | microRNA 4804 [Source:HGNC Symbol;Acc:HGNC:41720] | 23728 | 0.000 | -0.0639 | No |
| 84 | RN7SL616P | RNA, 7SL, cytoplasmic 616, pseudogene [Source:HGNC Symbol;Acc:HGNC:46632] | 25964 | 0.000 | -0.1244 | No |
| 85 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 26107 | 0.000 | -0.1282 | No |
| 86 | F2RL2 | coagulation factor II thrombin receptor like 2 [Source:HGNC Symbol;Acc:HGNC:3539] | 26114 | 0.000 | -0.1284 | No |
| 87 | LINC02056 | long intergenic non-protein coding RNA 2056 [Source:HGNC Symbol;Acc:HGNC:52898] | 26466 | 0.000 | -0.1379 | No |
| 88 | MARVELD2 | MARVEL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26401] | 26649 | 0.000 | -0.1428 | No |
| 89 | RNU6-724P | RNA, U6 small nuclear 724, pseudogene [Source:HGNC Symbol;Acc:HGNC:47687] | 27019 | 0.000 | -0.1528 | No |
| 90 | SERF1A | small EDRK-rich factor 1A [Source:HGNC Symbol;Acc:HGNC:10755] | 27517 | 0.000 | -0.1662 | No |
| 91 | SERF1B | small EDRK-rich factor 1B [Source:HGNC Symbol;Acc:HGNC:10756] | 27519 | 0.000 | -0.1663 | No |
| 92 | PIK3R1 | phosphoinositide-3-kinase regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:8979] | 28949 | -0.162 | -0.2024 | No |
| 93 | EEF1B2P2 | eukaryotic translation elongation factor 1 beta 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:3209] | 28995 | -0.173 | -0.2010 | No |
| 94 | POLK | DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183] | 29086 | -0.200 | -0.2004 | No |
| 95 | BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB [Source:HGNC Symbol;Acc:HGNC:13652] | 29237 | -0.229 | -0.2009 | No |
| 96 | TNPO1 | transportin 1 [Source:HGNC Symbol;Acc:HGNC:6401] | 29321 | -0.247 | -0.1994 | No |
| 97 | SV2C | synaptic vesicle glycoprotein 2C [Source:HGNC Symbol;Acc:HGNC:30670] | 29360 | -0.259 | -0.1965 | No |
| 98 | CERT1 | ceramide transporter 1 [Source:HGNC Symbol;Acc:HGNC:2205] | 29426 | -0.278 | -0.1940 | No |
| 99 | SLC30A5 | solute carrier family 30 member 5 [Source:HGNC Symbol;Acc:HGNC:19089] | 29520 | -0.304 | -0.1918 | No |
| 100 | HMGB1P35 | high mobility group box 1 pseudogene 35 [Source:HGNC Symbol;Acc:HGNC:39175] | 29775 | -0.320 | -0.1938 | No |
| 101 | PDCD5P2 | programmed cell death 5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:49886] | 29800 | -0.320 | -0.1896 | No |
| 102 | CHCHD2P2 | coiled-coil-helix-coiled-coil-helix domain containing 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:39586] | 29806 | -0.320 | -0.1848 | No |
| 103 | ZBED3 | zinc finger BED-type containing 3 [Source:HGNC Symbol;Acc:HGNC:20711] | 29915 | -0.320 | -0.1828 | No |
| 104 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 29920 | -0.320 | -0.1780 | No |
| 105 | RPL27AP5 | ribosomal protein L27a pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:36420] | 30336 | -0.402 | -0.1831 | No |
| 106 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 30420 | -0.426 | -0.1788 | No |
| 107 | POC5 | POC5 centriolar protein [Source:HGNC Symbol;Acc:HGNC:26658] | 30871 | -0.550 | -0.1826 | No |
| 108 | MRPS36 | mitochondrial ribosomal protein S36 [Source:HGNC Symbol;Acc:HGNC:16631] | 31850 | -0.832 | -0.1963 | No |
| 109 | NSA2 | NSA2 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:30728] | 32293 | -0.967 | -0.1935 | No |
| 110 | GFM2 | GTP dependent ribosome recycling factor mitochondrial 2 [Source:HGNC Symbol;Acc:HGNC:29682] | 32528 | -1.026 | -0.1841 | No |
| 111 | MCCC2 | methylcrotonoyl-CoA carboxylase 2 [Source:HGNC Symbol;Acc:HGNC:6937] | 32877 | -1.157 | -0.1758 | No |
| 112 | PTCD2 | pentatricopeptide repeat domain 2 [Source:HGNC Symbol;Acc:HGNC:25734] | 33143 | -1.260 | -0.1637 | No |
| 113 | SMN1 | survival of motor neuron 1, telomeric [Source:HGNC Symbol;Acc:HGNC:11117] | 33544 | -1.411 | -0.1529 | No |
| 114 | ZNF366 | zinc finger protein 366 [Source:HGNC Symbol;Acc:HGNC:18316] | 33736 | -1.488 | -0.1353 | No |
| 115 | FCHO2 | FCH and mu domain containing endocytic adaptor 2 [Source:HGNC Symbol;Acc:HGNC:25180] | 33977 | -1.607 | -0.1172 | No |
| 116 | FUNDC2P1 | FUN14 domain containing 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17253] | 34792 | -1.971 | -0.1091 | No |
| 117 | ANKRA2 | ankyrin repeat family A member 2 [Source:HGNC Symbol;Acc:HGNC:13208] | 35167 | -2.220 | -0.0852 | No |
| 118 | HEXB | hexosaminidase subunit beta [Source:HGNC Symbol;Acc:HGNC:4879] | 35691 | -2.606 | -0.0595 | No |
| 119 | PDE8B | phosphodiesterase 8B [Source:HGNC Symbol;Acc:HGNC:8794] | 35806 | -2.705 | -0.0212 | No |
| 120 | ENC1 | ectodermal-neural cortex 1 [Source:HGNC Symbol;Acc:HGNC:3345] | 36602 | -3.651 | 0.0132 | No |
