Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN |
| Enrichment Score (ES) | 0.86057526 |
| Normalized Enrichment Score (NES) | 2.088439 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 11 | 4.973 | 0.0232 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 18 | 4.941 | 0.0464 | Yes |
| 3 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 23 | 4.934 | 0.0696 | Yes |
| 4 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 31 | 4.888 | 0.0925 | Yes |
| 5 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 32 | 4.887 | 0.1155 | Yes |
| 6 | ACOD1 | aconitate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:33904] | 39 | 4.849 | 0.1383 | Yes |
| 7 | PHLDA1 | pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933] | 59 | 4.714 | 0.1600 | Yes |
| 8 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 64 | 4.668 | 0.1820 | Yes |
| 9 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 65 | 4.660 | 0.2040 | Yes |
| 10 | SOCS3 | suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391] | 68 | 4.638 | 0.2258 | Yes |
| 11 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 86 | 4.555 | 0.2469 | Yes |
| 12 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 102 | 4.467 | 0.2676 | Yes |
| 13 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 111 | 4.399 | 0.2882 | Yes |
| 14 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 112 | 4.395 | 0.3089 | Yes |
| 15 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 144 | 4.221 | 0.3280 | Yes |
| 16 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 161 | 4.111 | 0.3470 | Yes |
| 17 | ADORA2B | adenosine A2b receptor [Source:HGNC Symbol;Acc:HGNC:264] | 167 | 4.068 | 0.3661 | Yes |
| 18 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 188 | 3.979 | 0.3843 | Yes |
| 19 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 207 | 3.885 | 0.4022 | Yes |
| 20 | ITGA5 | integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141] | 215 | 3.865 | 0.4203 | Yes |
| 21 | PDLIM7 | PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958] | 242 | 3.750 | 0.4373 | Yes |
| 22 | TRAF1 | TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031] | 253 | 3.661 | 0.4543 | Yes |
| 23 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 260 | 3.637 | 0.4713 | Yes |
| 24 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 278 | 3.568 | 0.4877 | Yes |
| 25 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 296 | 3.500 | 0.5038 | Yes |
| 26 | CD83 | CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703] | 327 | 3.404 | 0.5190 | Yes |
| 27 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 344 | 3.346 | 0.5344 | Yes |
| 28 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 362 | 3.299 | 0.5495 | Yes |
| 29 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 371 | 3.286 | 0.5648 | Yes |
| 30 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 377 | 3.262 | 0.5801 | Yes |
| 31 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 382 | 3.251 | 0.5954 | Yes |
| 32 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 478 | 3.079 | 0.6073 | Yes |
| 33 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 490 | 3.044 | 0.6214 | Yes |
| 34 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 494 | 3.036 | 0.6357 | Yes |
| 35 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986] | 499 | 3.020 | 0.6498 | Yes |
| 36 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 530 | 2.956 | 0.6630 | Yes |
| 37 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 531 | 2.950 | 0.6769 | Yes |
| 38 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 537 | 2.939 | 0.6907 | Yes |
| 39 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 550 | 2.906 | 0.7041 | Yes |
| 40 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 581 | 2.818 | 0.7166 | Yes |
| 41 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 645 | 2.747 | 0.7278 | Yes |
| 42 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 667 | 2.711 | 0.7401 | Yes |
| 43 | PCDH7 | protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659] | 724 | 2.593 | 0.7508 | Yes |
| 44 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 743 | 2.557 | 0.7624 | Yes |
| 45 | IL18RAP | interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989] | 750 | 2.548 | 0.7743 | Yes |
| 46 | IKBKE | inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552] | 813 | 2.448 | 0.7842 | Yes |
| 47 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 817 | 2.434 | 0.7956 | Yes |
| 48 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 853 | 2.362 | 0.8058 | Yes |
| 49 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 871 | 2.327 | 0.8163 | Yes |
| 50 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 988 | 2.222 | 0.8237 | Yes |
| 51 | SRPRA | SRP receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:11307] | 1034 | 2.153 | 0.8327 | Yes |
| 52 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 1120 | 2.048 | 0.8400 | Yes |
| 53 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 1243 | 1.908 | 0.8457 | Yes |
| 54 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744] | 1324 | 1.850 | 0.8523 | Yes |
| 55 | RAC2 | Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802] | 1476 | 1.701 | 0.8563 | Yes |
| 56 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1599 | 1.608 | 0.8606 | Yes |
| 57 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 2700 | 1.063 | 0.8359 | No |
| 58 | RREB1 | ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449] | 4159 | 0.559 | 0.7991 | No |
| 59 | CDC42EP4 | CDC42 effector protein 4 [Source:HGNC Symbol;Acc:HGNC:17147] | 4161 | 0.558 | 0.8017 | No |
| 60 | BCL2L11 | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | 5028 | 0.333 | 0.7799 | No |
| 61 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 5460 | 0.226 | 0.7693 | No |
| 62 | UBB | ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] | 5576 | 0.200 | 0.7672 | No |
| 63 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 6032 | 0.090 | 0.7553 | No |
| 64 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6440 | 0.000 | 0.7443 | No |
| 65 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8967 | 0.000 | 0.6761 | No |
| 66 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13505 | 0.000 | 0.5535 | No |
| 67 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19539 | 0.000 | 0.3905 | No |
| 68 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 22998 | 0.000 | 0.2970 | No |
| 69 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27959 | 0.000 | 0.1630 | No |
| 70 | UBC | ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468] | 29041 | -0.186 | 0.1347 | No |
| 71 | TSC22D1 | TSC22 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:16826] | 31525 | -0.744 | 0.0711 | No |
| 72 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 31603 | -0.766 | 0.0727 | No |
| 73 | PKM | pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] | 32780 | -1.123 | 0.0462 | No |
| 74 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 33132 | -1.256 | 0.0426 | No |
| 75 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 33604 | -1.436 | 0.0367 | No |
| 76 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 34569 | -1.936 | 0.0198 | No |
| 77 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 34685 | -1.945 | 0.0259 | No |
| 78 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 34895 | -2.035 | 0.0298 | No |
| 79 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35491 | -2.438 | 0.0253 | No |
| 80 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 36682 | -3.791 | 0.0110 | No |
