Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.85813665 |
| Normalized Enrichment Score (NES) | 2.1207867 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 40 | 4.848 | 0.0357 | Yes |
| 2 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 66 | 4.648 | 0.0702 | Yes |
| 3 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 67 | 4.644 | 0.1054 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 110 | 4.400 | 0.1376 | Yes |
| 5 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 115 | 4.370 | 0.1706 | Yes |
| 6 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 118 | 4.359 | 0.2036 | Yes |
| 7 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 119 | 4.357 | 0.2366 | Yes |
| 8 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 120 | 4.356 | 0.2696 | Yes |
| 9 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 154 | 4.171 | 0.3004 | Yes |
| 10 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 213 | 3.868 | 0.3281 | Yes |
| 11 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 217 | 3.860 | 0.3573 | Yes |
| 12 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 222 | 3.839 | 0.3863 | Yes |
| 13 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 226 | 3.827 | 0.4152 | Yes |
| 14 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 245 | 3.725 | 0.4429 | Yes |
| 15 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 256 | 3.648 | 0.4703 | Yes |
| 16 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 262 | 3.624 | 0.4976 | Yes |
| 17 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 271 | 3.577 | 0.5245 | Yes |
| 18 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 310 | 3.434 | 0.5495 | Yes |
| 19 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 351 | 3.322 | 0.5736 | Yes |
| 20 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 409 | 3.191 | 0.5963 | Yes |
| 21 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 426 | 3.158 | 0.6197 | Yes |
| 22 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 463 | 3.136 | 0.6425 | Yes |
| 23 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 503 | 3.005 | 0.6643 | Yes |
| 24 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 521 | 2.963 | 0.6863 | Yes |
| 25 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 662 | 2.716 | 0.7031 | Yes |
| 26 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.7220 | Yes |
| 27 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 742 | 2.557 | 0.7403 | Yes |
| 28 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 843 | 2.382 | 0.7556 | Yes |
| 29 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 974 | 2.239 | 0.7691 | Yes |
| 30 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 1110 | 2.068 | 0.7811 | Yes |
| 31 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 1168 | 1.988 | 0.7946 | Yes |
| 32 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 1560 | 1.643 | 0.7965 | Yes |
| 33 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1589 | 1.620 | 0.8081 | Yes |
| 34 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 1647 | 1.573 | 0.8184 | Yes |
| 35 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 1781 | 1.487 | 0.8261 | Yes |
| 36 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 2157 | 1.369 | 0.8264 | Yes |
| 37 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 2520 | 1.154 | 0.8253 | Yes |
| 38 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 2654 | 1.087 | 0.8300 | Yes |
| 39 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 2677 | 1.076 | 0.8375 | Yes |
| 40 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 2684 | 1.073 | 0.8455 | Yes |
| 41 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 2737 | 1.053 | 0.8521 | Yes |
| 42 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 2800 | 1.023 | 0.8581 | Yes |
| 43 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 3560 | 0.745 | 0.8433 | No |
| 44 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 3569 | 0.742 | 0.8487 | No |
| 45 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 3771 | 0.688 | 0.8485 | No |
| 46 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 4031 | 0.597 | 0.8460 | No |
| 47 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 4097 | 0.578 | 0.8486 | No |
| 48 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 4207 | 0.544 | 0.8498 | No |
| 49 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 4931 | 0.359 | 0.8330 | No |
| 50 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 5213 | 0.283 | 0.8275 | No |
| 51 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 6193 | 0.046 | 0.8014 | No |
| 52 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 7269 | 0.000 | 0.7724 | No |
| 53 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7821 | 0.000 | 0.7575 | No |
| 54 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9336 | 0.000 | 0.7165 | No |
| 55 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 9947 | 0.000 | 0.7001 | No |
| 56 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10288 | 0.000 | 0.6909 | No |
| 57 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10588 | 0.000 | 0.6828 | No |
| 58 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12295 | 0.000 | 0.6367 | No |
| 59 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12519 | 0.000 | 0.6306 | No |
| 60 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12522 | 0.000 | 0.6306 | No |
| 61 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 13135 | 0.000 | 0.6140 | No |
| 62 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 13515 | 0.000 | 0.6038 | No |
| 63 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15812 | 0.000 | 0.5417 | No |
| 64 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17150 | 0.000 | 0.5056 | No |
| 65 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17812 | 0.000 | 0.4877 | No |
| 66 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 19022 | 0.000 | 0.4551 | No |
| 67 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19528 | 0.000 | 0.4414 | No |
| 68 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19935 | 0.000 | 0.4304 | No |
| 69 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 20342 | 0.000 | 0.4195 | No |
| 70 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 21002 | 0.000 | 0.4017 | No |
| 71 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 21087 | 0.000 | 0.3994 | No |
| 72 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 21677 | 0.000 | 0.3835 | No |
| 73 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 21948 | 0.000 | 0.3762 | No |
| 74 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 23261 | 0.000 | 0.3407 | No |
| 75 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 23391 | 0.000 | 0.3372 | No |
| 76 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 24669 | 0.000 | 0.3027 | No |
| 77 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 24854 | 0.000 | 0.2977 | No |
| 78 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 24872 | 0.000 | 0.2973 | No |
| 79 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 25445 | 0.000 | 0.2818 | No |
| 80 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 25458 | 0.000 | 0.2815 | No |
| 81 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 25646 | 0.000 | 0.2764 | No |
| 82 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 25784 | 0.000 | 0.2727 | No |
| 83 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 27063 | 0.000 | 0.2382 | No |
| 84 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 27077 | 0.000 | 0.2378 | No |
| 85 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 27702 | 0.000 | 0.2210 | No |
| 86 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27950 | 0.000 | 0.2143 | No |
| 87 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27961 | 0.000 | 0.2140 | No |
| 88 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 29559 | -0.313 | 0.1732 | No |
| 89 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 30657 | -0.486 | 0.1473 | No |
| 90 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 31833 | -0.827 | 0.1218 | No |
| 91 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 32925 | -1.174 | 0.1012 | No |
| 92 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 33752 | -1.497 | 0.0902 | No |
