Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.7712442 |
| Normalized Enrichment Score (NES) | -1.6312093 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.033211783 |
| FWER p-Value | 0.421 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1849 | 1.450 | -0.0390 | No |
| 2 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 2338 | 1.252 | -0.0426 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3155 | 0.884 | -0.0580 | No |
| 4 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 3363 | 0.815 | -0.0574 | No |
| 5 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 4338 | 0.513 | -0.0798 | No |
| 6 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 5253 | 0.277 | -0.1024 | No |
| 7 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12570 | 0.000 | -0.3001 | No |
| 8 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 12666 | 0.000 | -0.3027 | No |
| 9 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 14396 | 0.000 | -0.3494 | No |
| 10 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16738 | 0.000 | -0.4127 | No |
| 11 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18498 | 0.000 | -0.4602 | No |
| 12 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 24498 | 0.000 | -0.6224 | No |
| 13 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 25084 | 0.000 | -0.6382 | No |
| 14 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 28657 | -0.082 | -0.7341 | No |
| 15 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28769 | -0.115 | -0.7362 | No |
| 16 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 28890 | -0.146 | -0.7384 | No |
| 17 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 28920 | -0.154 | -0.7380 | No |
| 18 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 29088 | -0.200 | -0.7410 | No |
| 19 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 29122 | -0.206 | -0.7403 | No |
| 20 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 29243 | -0.230 | -0.7418 | No |
| 21 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29943 | -0.320 | -0.7582 | No |
| 22 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 30019 | -0.328 | -0.7578 | No |
| 23 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 30110 | -0.349 | -0.7576 | No |
| 24 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 30121 | -0.351 | -0.7552 | No |
| 25 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 30420 | -0.426 | -0.7600 | No |
| 26 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 30483 | -0.442 | -0.7583 | No |
| 27 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 30747 | -0.513 | -0.7615 | No |
| 28 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 30860 | -0.547 | -0.7604 | No |
| 29 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 31147 | -0.628 | -0.7633 | No |
| 30 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31441 | -0.711 | -0.7658 | Yes |
| 31 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 31444 | -0.711 | -0.7605 | Yes |
| 32 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 31540 | -0.748 | -0.7574 | Yes |
| 33 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 31646 | -0.773 | -0.7543 | Yes |
| 34 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 31998 | -0.873 | -0.7572 | Yes |
| 35 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 32040 | -0.887 | -0.7516 | Yes |
| 36 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 32162 | -0.925 | -0.7478 | Yes |
| 37 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 32174 | -0.931 | -0.7410 | Yes |
| 38 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 32238 | -0.950 | -0.7355 | Yes |
| 39 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 32385 | -0.996 | -0.7319 | Yes |
| 40 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 32593 | -1.049 | -0.7295 | Yes |
| 41 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 32625 | -1.063 | -0.7223 | Yes |
| 42 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 32643 | -1.068 | -0.7146 | Yes |
| 43 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 32746 | -1.113 | -0.7089 | Yes |
| 44 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32872 | -1.155 | -0.7035 | Yes |
| 45 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 33007 | -1.207 | -0.6979 | Yes |
| 46 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 33193 | -1.285 | -0.6932 | Yes |
| 47 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 33461 | -1.370 | -0.6900 | Yes |
| 48 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 33605 | -1.436 | -0.6829 | Yes |
| 49 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 33668 | -1.457 | -0.6735 | Yes |
| 50 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 33952 | -1.590 | -0.6691 | Yes |
| 51 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 33958 | -1.593 | -0.6571 | Yes |
| 52 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34106 | -1.671 | -0.6484 | Yes |
| 53 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34241 | -1.737 | -0.6388 | Yes |
| 54 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 34458 | -1.861 | -0.6305 | Yes |
| 55 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 34479 | -1.876 | -0.6168 | Yes |
| 56 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 34537 | -1.914 | -0.6038 | Yes |
| 57 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34557 | -1.928 | -0.5896 | Yes |
| 58 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 34559 | -1.929 | -0.5750 | Yes |
| 59 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 34768 | -1.957 | -0.5658 | Yes |
| 60 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 34808 | -1.985 | -0.5517 | Yes |
| 61 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 34857 | -2.014 | -0.5377 | Yes |
| 62 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34967 | -2.085 | -0.5248 | Yes |
| 63 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35009 | -2.109 | -0.5099 | Yes |
| 64 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35024 | -2.115 | -0.4942 | Yes |
| 65 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35034 | -2.123 | -0.4783 | Yes |
| 66 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35057 | -2.142 | -0.4626 | Yes |
| 67 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35073 | -2.150 | -0.4467 | Yes |
| 68 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35109 | -2.175 | -0.4311 | Yes |
| 69 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 35145 | -2.200 | -0.4153 | Yes |
| 70 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35150 | -2.203 | -0.3987 | Yes |
| 71 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35199 | -2.244 | -0.3830 | Yes |
| 72 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 35206 | -2.250 | -0.3660 | Yes |
| 73 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35241 | -2.264 | -0.3497 | Yes |
| 74 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 35354 | -2.343 | -0.3350 | Yes |
| 75 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35394 | -2.370 | -0.3180 | Yes |
| 76 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35642 | -2.564 | -0.3052 | Yes |
| 77 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 35689 | -2.604 | -0.2866 | Yes |
| 78 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 35757 | -2.659 | -0.2682 | Yes |
| 79 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 35760 | -2.660 | -0.2481 | Yes |
| 80 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 35912 | -2.745 | -0.2313 | Yes |
| 81 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 35959 | -2.812 | -0.2112 | Yes |
| 82 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35972 | -2.829 | -0.1900 | Yes |
| 83 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36044 | -2.930 | -0.1696 | Yes |
| 84 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36045 | -2.930 | -0.1474 | Yes |
| 85 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36073 | -2.962 | -0.1256 | Yes |
| 86 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36116 | -2.992 | -0.1040 | Yes |
| 87 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36175 | -3.068 | -0.0822 | Yes |
| 88 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36312 | -3.201 | -0.0616 | Yes |
| 89 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36482 | -3.462 | -0.0399 | Yes |
| 90 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36578 | -3.600 | -0.0151 | Yes |
| 91 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36686 | -3.799 | 0.0109 | Yes |
