Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.8847856 |
| Normalized Enrichment Score (NES) | 2.1565504 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 23 | 4.934 | 0.0256 | Yes |
| 2 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 30 | 4.888 | 0.0515 | Yes |
| 3 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 32 | 4.887 | 0.0775 | Yes |
| 4 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 64 | 4.668 | 0.1015 | Yes |
| 5 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 112 | 4.395 | 0.1236 | Yes |
| 6 | CEBPD | CCAAT enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835] | 114 | 4.384 | 0.1469 | Yes |
| 7 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 120 | 4.356 | 0.1700 | Yes |
| 8 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 136 | 4.283 | 0.1924 | Yes |
| 9 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 144 | 4.221 | 0.2146 | Yes |
| 10 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 161 | 4.111 | 0.2361 | Yes |
| 11 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 191 | 3.977 | 0.2565 | Yes |
| 12 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 207 | 3.885 | 0.2767 | Yes |
| 13 | RGS16 | regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997] | 221 | 3.840 | 0.2968 | Yes |
| 14 | IRGM | immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597] | 240 | 3.756 | 0.3163 | Yes |
| 15 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 260 | 3.637 | 0.3352 | Yes |
| 16 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 278 | 3.568 | 0.3537 | Yes |
| 17 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 310 | 3.434 | 0.3712 | Yes |
| 18 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 344 | 3.346 | 0.3881 | Yes |
| 19 | RHOC | ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669] | 353 | 3.317 | 0.4055 | Yes |
| 20 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 362 | 3.299 | 0.4229 | Yes |
| 21 | HCK | HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] | 364 | 3.290 | 0.4403 | Yes |
| 22 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 377 | 3.262 | 0.4574 | Yes |
| 23 | PNP | purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892] | 417 | 3.168 | 0.4732 | Yes |
| 24 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 420 | 3.167 | 0.4900 | Yes |
| 25 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 469 | 3.103 | 0.5052 | Yes |
| 26 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 476 | 3.082 | 0.5215 | Yes |
| 27 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 490 | 3.044 | 0.5373 | Yes |
| 28 | CLEC4D | C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554] | 506 | 2.999 | 0.5529 | Yes |
| 29 | STK10 | serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] | 519 | 2.968 | 0.5683 | Yes |
| 30 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 537 | 2.939 | 0.5835 | Yes |
| 31 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 550 | 2.906 | 0.5987 | Yes |
| 32 | CFLAR | CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876] | 626 | 2.780 | 0.6114 | Yes |
| 33 | SRGN | serglycin [Source:HGNC Symbol;Acc:HGNC:9361] | 638 | 2.756 | 0.6258 | Yes |
| 34 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 645 | 2.747 | 0.6403 | Yes |
| 35 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 667 | 2.711 | 0.6541 | Yes |
| 36 | GK | glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289] | 671 | 2.706 | 0.6685 | Yes |
| 37 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 698 | 2.643 | 0.6818 | Yes |
| 38 | MSR1 | macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376] | 720 | 2.600 | 0.6951 | Yes |
| 39 | ATF3 | activating transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:785] | 776 | 2.508 | 0.7070 | Yes |
| 40 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 784 | 2.496 | 0.7201 | Yes |
| 41 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 812 | 2.449 | 0.7324 | Yes |
| 42 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 842 | 2.384 | 0.7443 | Yes |
| 43 | IFRD1 | interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] | 844 | 2.382 | 0.7569 | Yes |
| 44 | LCP2 | lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529] | 887 | 2.295 | 0.7680 | Yes |
| 45 | MYO10 | myosin X [Source:HGNC Symbol;Acc:HGNC:7593] | 889 | 2.293 | 0.7802 | Yes |
| 46 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 1049 | 2.137 | 0.7873 | Yes |
| 47 | HCLS1 | hematopoietic cell-specific Lyn substrate 1 [Source:HGNC Symbol;Acc:HGNC:4844] | 1210 | 1.939 | 0.7933 | Yes |
| 48 | RNF11 | ring finger protein 11 [Source:HGNC Symbol;Acc:HGNC:10056] | 1229 | 1.925 | 0.8030 | Yes |
| 49 | APBB1IP | amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379] | 1316 | 1.860 | 0.8106 | Yes |
| 50 | ACSL4 | acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] | 1335 | 1.834 | 0.8199 | Yes |
| 51 | SLC20A1 | solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946] | 1345 | 1.824 | 0.8293 | Yes |
| 52 | SLC2A1 | solute carrier family 2 member 1 [Source:HGNC Symbol;Acc:HGNC:11005] | 1464 | 1.710 | 0.8352 | Yes |
| 53 | DEGS1 | delta 4-desaturase, sphingolipid 1 [Source:HGNC Symbol;Acc:HGNC:13709] | 1482 | 1.694 | 0.8438 | Yes |
| 54 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 1515 | 1.672 | 0.8518 | Yes |
| 55 | ETF1 | eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:HGNC:3477] | 1524 | 1.669 | 0.8605 | Yes |
| 56 | CLN3 | CLN3 lysosomal/endosomal transmembrane protein, battenin [Source:HGNC Symbol;Acc:HGNC:2074] | 1885 | 1.433 | 0.8584 | Yes |
| 57 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] | 2154 | 1.371 | 0.8585 | Yes |
| 58 | DAB2 | DAB adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:2662] | 2288 | 1.282 | 0.8617 | Yes |
| 59 | MAP2K1 | mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840] | 2327 | 1.257 | 0.8674 | Yes |
| 60 | EIF1 | eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:HGNC:3249] | 2369 | 1.231 | 0.8728 | Yes |
| 61 | TPST1 | tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020] | 2653 | 1.087 | 0.8709 | Yes |
| 62 | MLLT11 | MLLT11 transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997] | 2662 | 1.083 | 0.8765 | Yes |
| 63 | JUND | JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206] | 2756 | 1.043 | 0.8795 | Yes |
| 64 | WSB1 | WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221] | 2820 | 1.013 | 0.8832 | Yes |
| 65 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2950 | 0.951 | 0.8848 | Yes |
| 66 | TOP1 | DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986] | 3282 | 0.842 | 0.8803 | No |
| 67 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 3619 | 0.720 | 0.8751 | No |
| 68 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6440 | 0.000 | 0.7989 | No |
| 69 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8967 | 0.000 | 0.7306 | No |
| 70 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 11569 | 0.000 | 0.6603 | No |
| 71 | FCGR2B | Fc fragment of IgG receptor IIb [Source:HGNC Symbol;Acc:HGNC:3618] | 11583 | 0.000 | 0.6600 | No |
| 72 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 12666 | 0.000 | 0.6307 | No |
| 73 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13505 | 0.000 | 0.6081 | No |
| 74 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 22443 | 0.000 | 0.3666 | No |
| 75 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 24166 | 0.000 | 0.3201 | No |
| 76 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27959 | 0.000 | 0.2176 | No |
| 77 | MAPKAPK2 | MAPK activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887] | 28507 | -0.039 | 0.2030 | No |
| 78 | PRKCD | protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399] | 28553 | -0.052 | 0.2021 | No |
| 79 | RCN1 | reticulocalbin 1 [Source:HGNC Symbol;Acc:HGNC:9934] | 29391 | -0.269 | 0.1809 | No |
| 80 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 30273 | -0.386 | 0.1591 | No |
| 81 | KPNA3 | karyopherin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6396] | 30312 | -0.394 | 0.1602 | No |
| 82 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 30979 | -0.581 | 0.1453 | No |
| 83 | PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase type 1 beta [Source:HGNC Symbol;Acc:HGNC:8995] | 31590 | -0.763 | 0.1329 | No |
| 84 | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987] | 32427 | -1.011 | 0.1157 | No |
| 85 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 34569 | -1.936 | 0.0681 | No |
