Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.8701088 |
| Normalized Enrichment Score (NES) | 1.9690694 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.6647001E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 11 | 4.973 | 0.0574 | Yes |
| 2 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 15 | 4.957 | 0.1147 | Yes |
| 3 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 18 | 4.941 | 0.1720 | Yes |
| 4 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 23 | 4.934 | 0.2291 | Yes |
| 5 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 30 | 4.888 | 0.2856 | Yes |
| 6 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 31 | 4.888 | 0.3422 | Yes |
| 7 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 32 | 4.887 | 0.3989 | Yes |
| 8 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 33 | 4.883 | 0.4555 | Yes |
| 9 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 38 | 4.851 | 0.5116 | Yes |
| 10 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 58 | 4.730 | 0.5660 | Yes |
| 11 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 83 | 4.578 | 0.6184 | Yes |
| 12 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 144 | 4.221 | 0.6657 | Yes |
| 13 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 356 | 3.306 | 0.6984 | Yes |
| 14 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.7196 | Yes |
| 15 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 713 | 2.611 | 0.7496 | Yes |
| 16 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 756 | 2.543 | 0.7779 | Yes |
| 17 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 779 | 2.503 | 0.8064 | Yes |
| 18 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 1019 | 2.176 | 0.8251 | Yes |
| 19 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 1032 | 2.154 | 0.8498 | Yes |
| 20 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 1144 | 2.011 | 0.8701 | Yes |
| 21 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2206 | 1.337 | 0.8570 | No |
| 22 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 2402 | 1.214 | 0.8658 | No |
| 23 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2910 | 0.974 | 0.8634 | No |
| 24 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 3190 | 0.872 | 0.8660 | No |
| 25 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 5340 | 0.254 | 0.8109 | No |
| 26 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6430 | 0.000 | 0.7815 | No |
| 27 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6441 | 0.000 | 0.7812 | No |
| 28 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6444 | 0.000 | 0.7812 | No |
| 29 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13862 | 0.000 | 0.5810 | No |
| 30 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14849 | 0.000 | 0.5543 | No |
| 31 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14851 | 0.000 | 0.5543 | No |
| 32 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15895 | 0.000 | 0.5262 | No |
| 33 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15896 | 0.000 | 0.5262 | No |
| 34 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18307 | 0.000 | 0.4611 | No |
| 35 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19528 | 0.000 | 0.4282 | No |
| 36 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19537 | 0.000 | 0.4279 | No |
| 37 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 21666 | 0.000 | 0.3705 | No |
| 38 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 23397 | 0.000 | 0.3238 | No |
| 39 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 24359 | 0.000 | 0.2979 | No |
| 40 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27959 | 0.000 | 0.2007 | No |
| 41 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27961 | 0.000 | 0.2007 | No |
| 42 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 28136 | 0.000 | 0.1960 | No |
| 43 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 28687 | -0.089 | 0.1822 | No |
| 44 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 29479 | -0.293 | 0.1642 | No |
| 45 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 33865 | -1.546 | 0.0638 | No |
| 46 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 34844 | -2.007 | 0.0606 | No |
