Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | SANA_TNF_SIGNALING_UP |
| Enrichment Score (ES) | 0.7610579 |
| Normalized Enrichment Score (NES) | 1.8652772 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0055533815 |
| FWER p-Value | 0.058 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 40 | 4.848 | 0.0397 | Yes |
| 2 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 71 | 4.607 | 0.0777 | Yes |
| 3 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 110 | 4.400 | 0.1137 | Yes |
| 4 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 119 | 4.357 | 0.1502 | Yes |
| 5 | LIPG | lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623] | 126 | 4.326 | 0.1864 | Yes |
| 6 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 172 | 4.056 | 0.2193 | Yes |
| 7 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 199 | 3.919 | 0.2516 | Yes |
| 8 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 213 | 3.868 | 0.2838 | Yes |
| 9 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 222 | 3.839 | 0.3159 | Yes |
| 10 | SERPINE1 | serpin family E member 1 [Source:HGNC Symbol;Acc:HGNC:8583] | 239 | 3.764 | 0.3472 | Yes |
| 11 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 278 | 3.568 | 0.3762 | Yes |
| 12 | PLA1A | phospholipase A1 member A [Source:HGNC Symbol;Acc:HGNC:17661] | 337 | 3.365 | 0.4029 | Yes |
| 13 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 351 | 3.322 | 0.4305 | Yes |
| 14 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 377 | 3.262 | 0.4573 | Yes |
| 15 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 426 | 3.158 | 0.4826 | Yes |
| 16 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 503 | 3.005 | 0.5058 | Yes |
| 17 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 521 | 2.963 | 0.5303 | Yes |
| 18 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 531 | 2.950 | 0.5549 | Yes |
| 19 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 635 | 2.763 | 0.5754 | Yes |
| 20 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.5958 | Yes |
| 21 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 713 | 2.611 | 0.6175 | Yes |
| 22 | ITGAV | integrin subunit alpha V [Source:HGNC Symbol;Acc:HGNC:6150] | 783 | 2.497 | 0.6366 | Yes |
| 23 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 843 | 2.382 | 0.6551 | Yes |
| 24 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 871 | 2.327 | 0.6739 | Yes |
| 25 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 897 | 2.279 | 0.6924 | Yes |
| 26 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 988 | 2.222 | 0.7087 | Yes |
| 27 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 1029 | 2.158 | 0.7258 | Yes |
| 28 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 1168 | 1.988 | 0.7388 | Yes |
| 29 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1372 | 1.801 | 0.7485 | Yes |
| 30 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 2157 | 1.369 | 0.7388 | Yes |
| 31 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2206 | 1.337 | 0.7488 | Yes |
| 32 | FTH1 | ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976] | 2419 | 1.204 | 0.7532 | Yes |
| 33 | HLA-B | major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932] | 2855 | 0.999 | 0.7498 | Yes |
| 34 | DNAJA1 | DnaJ heat shock protein family (Hsp40) member A1 [Source:HGNC Symbol;Acc:HGNC:5229] | 3012 | 0.938 | 0.7535 | Yes |
| 35 | RABL3 | RAB, member of RAS oncogene family like 3 [Source:HGNC Symbol;Acc:HGNC:18072] | 3024 | 0.932 | 0.7611 | Yes |
| 36 | HLA-E | major histocompatibility complex, class I, E [Source:HGNC Symbol;Acc:HGNC:4962] | 3404 | 0.800 | 0.7576 | No |
| 37 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 3619 | 0.720 | 0.7578 | No |
| 38 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 3806 | 0.673 | 0.7585 | No |
| 39 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 4052 | 0.590 | 0.7568 | No |
| 40 | HLA-A | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931] | 4317 | 0.518 | 0.7540 | No |
| 41 | INHBA | inhibin subunit beta A [Source:HGNC Symbol;Acc:HGNC:6066] | 4623 | 0.436 | 0.7495 | No |
| 42 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925] | 5007 | 0.336 | 0.7420 | No |
| 43 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 5009 | 0.336 | 0.7448 | No |
| 44 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 5657 | 0.175 | 0.7287 | No |
| 45 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6410 | 0.000 | 0.7084 | No |
| 46 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6444 | 0.000 | 0.7075 | No |
| 47 | PDGFRL | platelet derived growth factor receptor like [Source:HGNC Symbol;Acc:HGNC:8805] | 7605 | 0.000 | 0.6762 | No |
| 48 | APOL1 | apolipoprotein L1 [Source:HGNC Symbol;Acc:HGNC:618] | 10138 | 0.000 | 0.6078 | No |
| 49 | APOL3 | apolipoprotein L3 [Source:HGNC Symbol;Acc:HGNC:14868] | 10140 | 0.000 | 0.6077 | No |
| 50 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10819 | 0.000 | 0.5894 | No |
| 51 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11174 | 0.000 | 0.5799 | No |
| 52 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11288 | 0.000 | 0.5768 | No |
| 53 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12511 | 0.000 | 0.5438 | No |
| 54 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12848 | 0.000 | 0.5347 | No |
| 55 | IL32 | interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] | 13897 | 0.000 | 0.5064 | No |
| 56 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13951 | 0.000 | 0.5050 | No |
| 57 | IL7R | interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024] | 13971 | 0.000 | 0.5044 | No |
| 58 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18307 | 0.000 | 0.3873 | No |
| 59 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18985 | 0.000 | 0.3690 | No |
| 60 | CTHRC1 | collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831] | 19011 | 0.000 | 0.3683 | No |
| 61 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 19179 | 0.000 | 0.3638 | No |
| 62 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19524 | 0.000 | 0.3545 | No |
| 63 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19528 | 0.000 | 0.3544 | No |
| 64 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19539 | 0.000 | 0.3542 | No |
| 65 | ANO9 | anoctamin 9 [Source:HGNC Symbol;Acc:HGNC:20679] | 22246 | 0.000 | 0.2811 | No |
| 66 | SSPN | sarcospan [Source:HGNC Symbol;Acc:HGNC:11322] | 24505 | 0.000 | 0.2200 | No |
| 67 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 25658 | 0.000 | 0.1889 | No |
| 68 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27950 | 0.000 | 0.1270 | No |
| 69 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27952 | 0.000 | 0.1270 | No |
| 70 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27961 | 0.000 | 0.1268 | No |
| 71 | ATP13A3 | ATPase 13A3 [Source:HGNC Symbol;Acc:HGNC:24113] | 28832 | -0.132 | 0.1044 | No |
| 72 | RAC3 | Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803] | 29119 | -0.204 | 0.0984 | No |
| 73 | DRAM1 | DNA damage regulated autophagy modulator 1 [Source:HGNC Symbol;Acc:HGNC:25645] | 30396 | -0.418 | 0.0674 | No |
| 74 | HSD17B11 | hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960] | 30616 | -0.479 | 0.0655 | No |
| 75 | DENND11 | DENN domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29472] | 31053 | -0.603 | 0.0588 | No |
| 76 | NCEH1 | neutral cholesterol ester hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:29260] | 31313 | -0.673 | 0.0575 | No |
| 77 | SPAG9 | sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524] | 32055 | -0.892 | 0.0450 | No |
| 78 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 33132 | -1.256 | 0.0265 | No |
| 79 | C1QTNF1 | C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324] | 33212 | -1.291 | 0.0352 | No |
| 80 | BPGM | bisphosphoglycerate mutase [Source:HGNC Symbol;Acc:HGNC:1093] | 33727 | -1.484 | 0.0338 | No |
| 81 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 33995 | -1.617 | 0.0402 | No |
| 82 | SMAD3 | SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769] | 35651 | -2.573 | 0.0171 | No |
| 83 | OXR1 | oxidation resistance 1 [Source:HGNC Symbol;Acc:HGNC:15822] | 35665 | -2.582 | 0.0385 | No |
