Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.77812165 |
| Normalized Enrichment Score (NES) | 1.8723907 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.004933465 |
| FWER p-Value | 0.048 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 33 | 4.883 | 0.0321 | Yes |
| 2 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 52 | 4.782 | 0.0639 | Yes |
| 3 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 57 | 4.736 | 0.0958 | Yes |
| 4 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 65 | 4.660 | 0.1270 | Yes |
| 5 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 67 | 4.644 | 0.1584 | Yes |
| 6 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 71 | 4.607 | 0.1894 | Yes |
| 7 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 75 | 4.603 | 0.2204 | Yes |
| 8 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 86 | 4.555 | 0.2509 | Yes |
| 9 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 94 | 4.505 | 0.2811 | Yes |
| 10 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 100 | 4.475 | 0.3112 | Yes |
| 11 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 162 | 4.109 | 0.3373 | Yes |
| 12 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 208 | 3.879 | 0.3623 | Yes |
| 13 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 278 | 3.568 | 0.3845 | Yes |
| 14 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 280 | 3.557 | 0.4085 | Yes |
| 15 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 285 | 3.544 | 0.4323 | Yes |
| 16 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 377 | 3.262 | 0.4519 | Yes |
| 17 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 404 | 3.204 | 0.4728 | Yes |
| 18 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 474 | 3.083 | 0.4918 | Yes |
| 19 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 476 | 3.082 | 0.5126 | Yes |
| 20 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 485 | 3.051 | 0.5330 | Yes |
| 21 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 490 | 3.044 | 0.5534 | Yes |
| 22 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 531 | 2.950 | 0.5722 | Yes |
| 23 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 550 | 2.906 | 0.5914 | Yes |
| 24 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 635 | 2.763 | 0.6078 | Yes |
| 25 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 684 | 2.677 | 0.6245 | Yes |
| 26 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.6419 | Yes |
| 27 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 713 | 2.611 | 0.6592 | Yes |
| 28 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 731 | 2.577 | 0.6762 | Yes |
| 29 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 743 | 2.557 | 0.6931 | Yes |
| 30 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 798 | 2.474 | 0.7084 | Yes |
| 31 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 988 | 2.222 | 0.7183 | Yes |
| 32 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 1029 | 2.158 | 0.7318 | Yes |
| 33 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 1244 | 1.908 | 0.7389 | Yes |
| 34 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 1365 | 1.806 | 0.7478 | Yes |
| 35 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1372 | 1.801 | 0.7598 | Yes |
| 36 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 1478 | 1.700 | 0.7685 | Yes |
| 37 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1599 | 1.608 | 0.7761 | Yes |
| 38 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1883 | 1.434 | 0.7781 | Yes |
| 39 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 2225 | 1.327 | 0.7779 | No |
| 40 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 3302 | 0.834 | 0.7544 | No |
| 41 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 3674 | 0.696 | 0.7491 | No |
| 42 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 3855 | 0.658 | 0.7487 | No |
| 43 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 4097 | 0.578 | 0.7461 | No |
| 44 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 4351 | 0.510 | 0.7427 | No |
| 45 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 5009 | 0.336 | 0.7272 | No |
| 46 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 7225 | 0.000 | 0.6674 | No |
| 47 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8716 | 0.000 | 0.6271 | No |
| 48 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8852 | 0.000 | 0.6235 | No |
| 49 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10403 | 0.000 | 0.5816 | No |
| 50 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11288 | 0.000 | 0.5577 | No |
| 51 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11599 | 0.000 | 0.5493 | No |
| 52 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13951 | 0.000 | 0.4858 | No |
| 53 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 17822 | 0.000 | 0.3812 | No |
| 54 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 18080 | 0.000 | 0.3743 | No |
| 55 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18307 | 0.000 | 0.3682 | No |
| 56 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18950 | 0.000 | 0.3508 | No |
| 57 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 19072 | 0.000 | 0.3476 | No |
| 58 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19524 | 0.000 | 0.3354 | No |
| 59 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19537 | 0.000 | 0.3351 | No |
| 60 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19539 | 0.000 | 0.3350 | No |
| 61 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 19946 | 0.000 | 0.3241 | No |
| 62 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 24166 | 0.000 | 0.2101 | No |
| 63 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 24772 | 0.000 | 0.1937 | No |
| 64 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 27106 | 0.000 | 0.1307 | No |
| 65 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 27144 | 0.000 | 0.1297 | No |
| 66 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27952 | 0.000 | 0.1079 | No |
| 67 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27959 | 0.000 | 0.1077 | No |
| 68 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27961 | 0.000 | 0.1077 | No |
| 69 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 29161 | -0.214 | 0.0768 | No |
| 70 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 29405 | -0.272 | 0.0720 | No |
| 71 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 31270 | -0.658 | 0.0261 | No |
| 72 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 32925 | -1.174 | -0.0106 | No |
| 73 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 34167 | -1.704 | -0.0327 | No |
| 74 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 35397 | -2.373 | -0.0498 | No |
| 75 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 35569 | -2.497 | -0.0376 | No |
| 76 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 36085 | -2.973 | -0.0314 | No |
| 77 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 36865 | -4.135 | -0.0246 | No |
| 78 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 36994 | -4.534 | 0.0026 | No |
