Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | WP_LUNG_FIBROSIS |
| Enrichment Score (ES) | 0.80381614 |
| Normalized Enrichment Score (NES) | 1.861462 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0057464503 |
| FWER p-Value | 0.063 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 11 | 4.973 | 0.0536 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 18 | 4.941 | 0.1069 | Yes |
| 3 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 31 | 4.888 | 0.1595 | Yes |
| 4 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 58 | 4.730 | 0.2101 | Yes |
| 5 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 66 | 4.648 | 0.2602 | Yes |
| 6 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 83 | 4.578 | 0.3094 | Yes |
| 7 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 104 | 4.459 | 0.3571 | Yes |
| 8 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 144 | 4.221 | 0.4018 | Yes |
| 9 | CCR3 | C-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:1604] | 168 | 4.063 | 0.4452 | Yes |
| 10 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 173 | 4.054 | 0.4890 | Yes |
| 11 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 293 | 3.515 | 0.5238 | Yes |
| 12 | SMAD7 | SMAD family member 7 [Source:HGNC Symbol;Acc:HGNC:6773] | 355 | 3.310 | 0.5581 | Yes |
| 13 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 482 | 3.063 | 0.5878 | Yes |
| 14 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 530 | 2.956 | 0.6186 | Yes |
| 15 | SKIL | SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897] | 533 | 2.947 | 0.6504 | Yes |
| 16 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 784 | 2.496 | 0.6707 | Yes |
| 17 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 817 | 2.434 | 0.6962 | Yes |
| 18 | DSP | desmoplakin [Source:HGNC Symbol;Acc:HGNC:3052] | 918 | 2.252 | 0.7179 | Yes |
| 19 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 1234 | 1.914 | 0.7301 | Yes |
| 20 | MMP2 | matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166] | 1258 | 1.893 | 0.7500 | Yes |
| 21 | DPP9 | dipeptidyl peptidase 9 [Source:HGNC Symbol;Acc:HGNC:18648] | 1310 | 1.863 | 0.7688 | Yes |
| 22 | HMOX1 | heme oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:5013] | 1763 | 1.497 | 0.7728 | Yes |
| 23 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2206 | 1.337 | 0.7754 | Yes |
| 24 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 2402 | 1.214 | 0.7833 | Yes |
| 25 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 2700 | 1.063 | 0.7868 | Yes |
| 26 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2910 | 0.974 | 0.7917 | Yes |
| 27 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 2999 | 0.944 | 0.7995 | Yes |
| 28 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 3190 | 0.872 | 0.8038 | Yes |
| 29 | NFE2L2 | nuclear factor, erythroid 2 like 2 [Source:HGNC Symbol;Acc:HGNC:7782] | 3813 | 0.671 | 0.7943 | No |
| 30 | HGF | hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893] | 3878 | 0.649 | 0.7996 | No |
| 31 | TERT | telomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730] | 5193 | 0.287 | 0.7672 | No |
| 32 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6410 | 0.000 | 0.7344 | No |
| 33 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8335 | 0.000 | 0.6824 | No |
| 34 | CALCA | calcitonin related polypeptide alpha [Source:HGNC Symbol;Acc:HGNC:1437] | 8861 | 0.000 | 0.6682 | No |
| 35 | FAM13A | family with sequence similarity 13 member A [Source:HGNC Symbol;Acc:HGNC:19367] | 10448 | 0.000 | 0.6254 | No |
| 36 | SFTPA2 | surfactant protein A2 [Source:HGNC Symbol;Acc:HGNC:10799] | 11916 | 0.000 | 0.5858 | No |
| 37 | CMA1 | chymase 1 [Source:HGNC Symbol;Acc:HGNC:2097] | 11925 | 0.000 | 0.5856 | No |
| 38 | SFTPA1 | surfactant protein A1 [Source:HGNC Symbol;Acc:HGNC:10798] | 11929 | 0.000 | 0.5855 | No |
| 39 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12494 | 0.000 | 0.5702 | No |
| 40 | IL13 | interleukin 13 [Source:HGNC Symbol;Acc:HGNC:5973] | 13860 | 0.000 | 0.5334 | No |
| 41 | ELN | elastin [Source:HGNC Symbol;Acc:HGNC:3327] | 16403 | 0.000 | 0.4647 | No |
| 42 | IL4 | interleukin 4 [Source:HGNC Symbol;Acc:HGNC:6014] | 17755 | 0.000 | 0.4282 | No |
| 43 | IL5 | interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016] | 17757 | 0.000 | 0.4282 | No |
| 44 | SERPINA1 | serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941] | 17824 | 0.000 | 0.4264 | No |
| 45 | BMP7 | bone morphogenetic protein 7 [Source:HGNC Symbol;Acc:HGNC:1074] | 19143 | 0.000 | 0.3908 | No |
| 46 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19528 | 0.000 | 0.3805 | No |
| 47 | CYSLTR2 | cysteinyl leukotriene receptor 2 [Source:HGNC Symbol;Acc:HGNC:18274] | 20087 | 0.000 | 0.3654 | No |
| 48 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 20166 | 0.000 | 0.3633 | No |
| 49 | SFTPC | surfactant protein C [Source:HGNC Symbol;Acc:HGNC:10802] | 21432 | 0.000 | 0.3291 | No |
| 50 | MUC5B | mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516] | 21580 | 0.000 | 0.3252 | No |
| 51 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 21666 | 0.000 | 0.3229 | No |
| 52 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 22712 | 0.000 | 0.2946 | No |
| 53 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 22713 | 0.000 | 0.2946 | No |
| 54 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27959 | 0.000 | 0.1530 | No |
| 55 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27961 | 0.000 | 0.1530 | No |
| 56 | CCN2 | cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500] | 27990 | 0.000 | 0.1522 | No |
| 57 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 28516 | -0.041 | 0.1385 | No |
| 58 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 29078 | -0.197 | 0.1255 | No |
| 59 | STN1 | STN1 subunit of CST complex [Source:HGNC Symbol;Acc:HGNC:26200] | 33173 | -1.272 | 0.0287 | No |
| 60 | RTEL1 | regulator of telomere elongation helicase 1 [Source:HGNC Symbol;Acc:HGNC:15888] | 33446 | -1.363 | 0.0361 | No |
| 61 | PARN | poly(A)-specific ribonuclease [Source:HGNC Symbol;Acc:HGNC:8609] | 33458 | -1.369 | 0.0506 | No |
| 62 | ATP11A | ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552] | 33567 | -1.420 | 0.0631 | No |
| 63 | PLAU | plasminogen activator, urokinase [Source:HGNC Symbol;Acc:HGNC:9052] | 36069 | -2.957 | 0.0276 | No |
