Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GGGNNTTTCC_NFKB_Q6_01 |
| Enrichment Score (ES) | 0.5032953 |
| Normalized Enrichment Score (NES) | 1.2943649 |
| Nominal p-value | 0.0121951215 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 23 | 4.934 | 0.0290 | Yes |
| 2 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 30 | 4.888 | 0.0581 | Yes |
| 3 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 31 | 4.888 | 0.0875 | Yes |
| 4 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 64 | 4.668 | 0.1146 | Yes |
| 5 | CCDC80 | coiled-coil domain containing 80 [Source:HGNC Symbol;Acc:HGNC:30649] | 69 | 4.634 | 0.1423 | Yes |
| 6 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 102 | 4.467 | 0.1682 | Yes |
| 7 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 123 | 4.338 | 0.1937 | Yes |
| 8 | BATF | basic leucine zipper ATF-like transcription factor [Source:HGNC Symbol;Acc:HGNC:958] | 238 | 3.774 | 0.2133 | Yes |
| 9 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 278 | 3.568 | 0.2336 | Yes |
| 10 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 356 | 3.306 | 0.2514 | Yes |
| 11 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 377 | 3.262 | 0.2704 | Yes |
| 12 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 404 | 3.204 | 0.2890 | Yes |
| 13 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 407 | 3.197 | 0.3081 | Yes |
| 14 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 581 | 2.818 | 0.3203 | Yes |
| 15 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 728 | 2.585 | 0.3319 | Yes |
| 16 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 743 | 2.557 | 0.3468 | Yes |
| 17 | KY | kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576] | 773 | 2.512 | 0.3611 | Yes |
| 18 | SH2B3 | SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605] | 868 | 2.339 | 0.3726 | Yes |
| 19 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 921 | 2.252 | 0.3847 | Yes |
| 20 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 1234 | 1.914 | 0.3878 | Yes |
| 21 | FHL3 | four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704] | 1305 | 1.866 | 0.3971 | Yes |
| 22 | RYBP | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | 1483 | 1.694 | 0.4024 | Yes |
| 23 | ORAI1 | ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] | 1516 | 1.671 | 0.4116 | Yes |
| 24 | RAP2C | RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165] | 1593 | 1.615 | 0.4192 | Yes |
| 25 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 1609 | 1.599 | 0.4284 | Yes |
| 26 | CPEB4 | cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747] | 1703 | 1.533 | 0.4351 | Yes |
| 27 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 1898 | 1.427 | 0.4384 | Yes |
| 28 | CXCR5 | C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060] | 2022 | 1.376 | 0.4433 | Yes |
| 29 | WNT10A | Wnt family member 10A [Source:HGNC Symbol;Acc:HGNC:13829] | 2447 | 1.194 | 0.4390 | Yes |
| 30 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 2487 | 1.174 | 0.4450 | Yes |
| 31 | G3BP1 | G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292] | 2498 | 1.168 | 0.4518 | Yes |
| 32 | GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804] | 2556 | 1.135 | 0.4570 | Yes |
| 33 | TCEA2 | transcription elongation factor A2 [Source:HGNC Symbol;Acc:HGNC:11614] | 2762 | 1.041 | 0.4577 | Yes |
| 34 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 2832 | 1.011 | 0.4619 | Yes |
| 35 | ZFAND3 | zinc finger AN1-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18019] | 2871 | 0.988 | 0.4668 | Yes |
| 36 | UBE2M | ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491] | 2897 | 0.978 | 0.4720 | Yes |
| 37 | SLAMF8 | SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391] | 2907 | 0.975 | 0.4776 | Yes |
| 38 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2910 | 0.974 | 0.4834 | Yes |
| 39 | IER5 | immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393] | 2916 | 0.971 | 0.4891 | Yes |
| 40 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2950 | 0.951 | 0.4939 | Yes |
| 41 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 3168 | 0.881 | 0.4933 | Yes |
| 42 | TPM3 | tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012] | 3182 | 0.874 | 0.4982 | Yes |
| 43 | BMP2K | BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041] | 3189 | 0.872 | 0.5033 | Yes |
| 44 | RASSF2 | Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883] | 3418 | 0.796 | 0.5019 | No |
| 45 | SMPD3 | sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240] | 3777 | 0.687 | 0.4963 | No |
| 46 | TNKS1BP1 | tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081] | 3781 | 0.686 | 0.5004 | No |
| 47 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 4602 | 0.441 | 0.4808 | No |
| 48 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 4723 | 0.409 | 0.4800 | No |
| 49 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 4864 | 0.380 | 0.4785 | No |
| 50 | N4BP1 | NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850] | 4912 | 0.365 | 0.4794 | No |
| 51 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 5009 | 0.336 | 0.4789 | No |
| 52 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 5371 | 0.246 | 0.4706 | No |
| 53 | RBMS1 | RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907] | 5384 | 0.242 | 0.4717 | No |
| 54 | WRAP53 | WD repeat containing antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522] | 5624 | 0.183 | 0.4663 | No |
| 55 | RPS6KA4 | ribosomal protein S6 kinase A4 [Source:HGNC Symbol;Acc:HGNC:10433] | 5987 | 0.101 | 0.4571 | No |
| 56 | UPF2 | UPF2 regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854] | 6063 | 0.080 | 0.4556 | No |
| 57 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 6106 | 0.065 | 0.4548 | No |
| 58 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8335 | 0.000 | 0.3946 | No |
| 59 | POU2F3 | POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:19864] | 8532 | 0.000 | 0.3893 | No |
| 60 | PRR34 | PRR34 long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:25606] | 8972 | 0.000 | 0.3774 | No |
| 61 | MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765] | 9234 | 0.000 | 0.3703 | No |
| 62 | TNFRSF9 | TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] | 9855 | 0.000 | 0.3535 | No |
| 63 | KCNS3 | potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] | 9971 | 0.000 | 0.3504 | No |
| 64 | IL1RAPL1 | interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996] | 10478 | 0.000 | 0.3367 | No |
| 65 | NRIP2 | nuclear receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23078] | 10902 | 0.000 | 0.3253 | No |
| 66 | NTRK3 | neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033] | 11027 | 0.000 | 0.3219 | No |
| 67 | SP6 | Sp6 transcription factor [Source:HGNC Symbol;Acc:HGNC:14530] | 12426 | 0.000 | 0.2841 | No |
| 68 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12549 | 0.000 | 0.2808 | No |
| 69 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12848 | 0.000 | 0.2727 | No |
| 70 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13597 | 0.000 | 0.2525 | No |
| 71 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14416 | 0.000 | 0.2304 | No |
| 72 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16273 | 0.000 | 0.1801 | No |
| 73 | IL2 | interleukin 2 [Source:HGNC Symbol;Acc:HGNC:6001] | 17754 | 0.000 | 0.1401 | No |
| 74 | LPO | lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] | 18746 | 0.000 | 0.1133 | No |
| 75 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19125 | 0.000 | 0.1031 | No |
| 76 | BNC2 | basonuclin 2 [Source:HGNC Symbol;Acc:HGNC:30988] | 19346 | 0.000 | 0.0971 | No |
| 77 | NR2F2 | nuclear receptor subfamily 2 group F member 2 [Source:HGNC Symbol;Acc:HGNC:7976] | 19642 | 0.000 | 0.0891 | No |
| 78 | CNTF | ciliary neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:2169] | 20171 | 0.000 | 0.0748 | No |
| 79 | C1QL1 | complement C1q like 1 [Source:HGNC Symbol;Acc:HGNC:24182] | 20322 | 0.000 | 0.0708 | No |
| 80 | ENTHD1 | ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352] | 20494 | 0.000 | 0.0662 | No |
| 81 | FOXS1 | forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735] | 20539 | 0.000 | 0.0650 | No |
| 82 | LAMA1 | laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481] | 20844 | 0.000 | 0.0567 | No |
| 83 | NRGN | neurogranin [Source:HGNC Symbol;Acc:HGNC:8000] | 21295 | 0.000 | 0.0446 | No |
| 84 | FTHL17 | ferritin heavy chain like 17 [Source:HGNC Symbol;Acc:HGNC:3987] | 21563 | 0.000 | 0.0373 | No |
| 85 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 22712 | 0.000 | 0.0063 | No |
| 86 | SOX5 | SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201] | 23489 | 0.000 | -0.0147 | No |
| 87 | ZNF532 | zinc finger protein 532 [Source:HGNC Symbol;Acc:HGNC:30940] | 26814 | 0.000 | -0.1047 | No |
| 88 | CD70 | CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937] | 28114 | 0.000 | -0.1398 | No |
| 89 | RSPRY1 | ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420] | 28471 | -0.027 | -0.1493 | No |
| 90 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 28514 | -0.040 | -0.1502 | No |
| 91 | ARID1A | AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110] | 28604 | -0.064 | -0.1522 | No |
| 92 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon [Source:HGNC Symbol;Acc:HGNC:9313] | 28751 | -0.110 | -0.1555 | No |
| 93 | DCLK1 | doublecortin like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2700] | 28894 | -0.148 | -0.1585 | No |
| 94 | UBE2H | ubiquitin conjugating enzyme E2 H [Source:HGNC Symbol;Acc:HGNC:12484] | 29084 | -0.199 | -0.1624 | No |
| 95 | PLXNB1 | plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103] | 29092 | -0.201 | -0.1614 | No |
| 96 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 29220 | -0.226 | -0.1634 | No |
| 97 | FUT7 | fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018] | 29517 | -0.303 | -0.1696 | No |
| 98 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 30273 | -0.386 | -0.1877 | No |
| 99 | PSME3IP1 | proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856] | 31000 | -0.590 | -0.2038 | No |
| 100 | ENO3 | enolase 3 [Source:HGNC Symbol;Acc:HGNC:3354] | 31335 | -0.682 | -0.2088 | No |
| 101 | CDC27 | cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728] | 31586 | -0.760 | -0.2110 | No |
| 102 | MIDEAS | mitotic deacetylase associated SANT domain protein [Source:HGNC Symbol;Acc:HGNC:19853] | 31799 | -0.816 | -0.2118 | No |
| 103 | CNTNAP1 | contactin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:8011] | 31920 | -0.855 | -0.2100 | No |
| 104 | JAK3 | Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193] | 32233 | -0.949 | -0.2127 | No |
| 105 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 32238 | -0.950 | -0.2071 | No |
| 106 | SLC25A18 | solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988] | 32298 | -0.969 | -0.2029 | No |
| 107 | CREB1 | cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345] | 32355 | -0.986 | -0.1985 | No |
| 108 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 32400 | -1.001 | -0.1937 | No |
| 109 | SH3KBP1 | SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867] | 32588 | -1.046 | -0.1925 | No |
| 110 | CCDC107 | coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465] | 32677 | -1.079 | -0.1884 | No |
| 111 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 32902 | -1.167 | -0.1874 | No |
| 112 | GEM | GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] | 32919 | -1.171 | -0.1808 | No |
| 113 | PKN1 | protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405] | 32924 | -1.173 | -0.1739 | No |
| 114 | SLC44A1 | solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798] | 32969 | -1.192 | -0.1679 | No |
| 115 | PNKD | PNKD metallo-beta-lactamase domain containing [Source:HGNC Symbol;Acc:HGNC:9153] | 33206 | -1.289 | -0.1666 | No |
| 116 | ALG6 | ALG6 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157] | 33533 | -1.403 | -0.1670 | No |
| 117 | STX4 | syntaxin 4 [Source:HGNC Symbol;Acc:HGNC:11439] | 33609 | -1.439 | -0.1604 | No |
| 118 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 33823 | -1.532 | -0.1570 | No |
| 119 | KAT7 | lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016] | 34000 | -1.621 | -0.1520 | No |
| 120 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 34434 | -1.845 | -0.1526 | No |
| 121 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 34685 | -1.945 | -0.1477 | No |
| 122 | SLC6A12 | solute carrier family 6 member 12 [Source:HGNC Symbol;Acc:HGNC:11045] | 34800 | -1.979 | -0.1389 | No |
| 123 | CYLD | CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584] | 34838 | -2.004 | -0.1279 | No |
| 124 | HOXA4 | homeobox A4 [Source:HGNC Symbol;Acc:HGNC:5105] | 35040 | -2.130 | -0.1206 | No |
| 125 | HIVEP1 | HIVEP zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4920] | 35280 | -2.294 | -0.1133 | No |
| 126 | S1PR2 | sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169] | 35525 | -2.468 | -0.1051 | No |
| 127 | CHD6 | chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057] | 35612 | -2.535 | -0.0922 | No |
| 128 | LIX1L | limb and CNS expressed 1 like [Source:HGNC Symbol;Acc:HGNC:28715] | 35771 | -2.672 | -0.0804 | No |
| 129 | CALCOCO1 | calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306] | 35903 | -2.735 | -0.0676 | No |
| 130 | TOM1L1 | target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983] | 35904 | -2.735 | -0.0512 | No |
| 131 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 35954 | -2.799 | -0.0357 | No |
| 132 | TRIM47 | tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020] | 36360 | -3.281 | -0.0270 | No |
| 133 | FAM117A | family with sequence similarity 117 member A [Source:HGNC Symbol;Acc:HGNC:24179] | 36534 | -3.519 | -0.0105 | No |
| 134 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 36912 | -4.259 | 0.0048 | No |
