Fig 1: Enrichment plot: MIR6742_5P
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | MIR6742_5P |
| Enrichment Score (ES) | -0.7526241 |
| Normalized Enrichment Score (NES) | -1.4681023 |
| Nominal p-value | 0.011157601 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SYN1 | synapsin I [Source:HGNC Symbol;Acc:HGNC:11494] | 2670 | 1.080 | -0.0467 | No |
| 2 | PSME3 | proteasome activator subunit 3 [Source:HGNC Symbol;Acc:HGNC:9570] | 3516 | 0.762 | -0.0516 | No |
| 3 | TNKS1BP1 | tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081] | 3781 | 0.686 | -0.0426 | No |
| 4 | AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:324] | 3969 | 0.618 | -0.0332 | No |
| 5 | F11R | F11 receptor [Source:HGNC Symbol;Acc:HGNC:14685] | 4101 | 0.575 | -0.0232 | No |
| 6 | PRSS33 | serine protease 33 [Source:HGNC Symbol;Acc:HGNC:30405] | 6447 | 0.000 | -0.0865 | No |
| 7 | CYP26B1 | cytochrome P450 family 26 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:20581] | 6971 | 0.000 | -0.1006 | No |
| 8 | ASGR2 | asialoglycoprotein receptor 2 [Source:HGNC Symbol;Acc:HGNC:743] | 7019 | 0.000 | -0.1019 | No |
| 9 | PCBD1 | pterin-4 alpha-carbinolamine dehydratase 1 [Source:HGNC Symbol;Acc:HGNC:8646] | 7484 | 0.000 | -0.1144 | No |
| 10 | ZNF138 | zinc finger protein 138 [Source:HGNC Symbol;Acc:HGNC:12922] | 9424 | 0.000 | -0.1668 | No |
| 11 | KCNS2 | potassium voltage-gated channel modifier subfamily S member 2 [Source:HGNC Symbol;Acc:HGNC:6301] | 9970 | 0.000 | -0.1815 | No |
| 12 | SPATA31D4 | SPATA31 subfamily D member 4 [Source:HGNC Symbol;Acc:HGNC:38601] | 10040 | 0.000 | -0.1833 | No |
| 13 | EMX2 | empty spiracles homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3341] | 10473 | 0.000 | -0.1950 | No |
| 14 | NTSR1 | neurotensin receptor 1 [Source:HGNC Symbol;Acc:HGNC:8039] | 11972 | 0.000 | -0.2354 | No |
| 15 | G6PC2 | glucose-6-phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:28906] | 12421 | 0.000 | -0.2475 | No |
| 16 | IGF2 | insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] | 12510 | 0.000 | -0.2499 | No |
| 17 | CORIN | corin, serine peptidase [Source:HGNC Symbol;Acc:HGNC:19012] | 13502 | 0.000 | -0.2766 | No |
| 18 | DMGDH | dimethylglycine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24475] | 13778 | 0.000 | -0.2841 | No |
| 19 | FBXO41 | F-box protein 41 [Source:HGNC Symbol;Acc:HGNC:29409] | 15572 | 0.000 | -0.3325 | No |
| 20 | SEMA6A | semaphorin 6A [Source:HGNC Symbol;Acc:HGNC:10738] | 17876 | 0.000 | -0.3946 | No |
| 21 | TRNP1 | TMF1 regulated nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:34348] | 19559 | 0.000 | -0.4400 | No |
| 22 | SCGB2B2 | secretoglobin family 2B member 2 [Source:HGNC Symbol;Acc:HGNC:27616] | 20991 | 0.000 | -0.4787 | No |
| 23 | DIRAS2 | DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323] | 24392 | 0.000 | -0.5704 | No |
| 24 | TMEM132B | transmembrane protein 132B [Source:HGNC Symbol;Acc:HGNC:29397] | 27552 | 0.000 | -0.6557 | No |
| 25 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 29266 | -0.234 | -0.6965 | No |
| 26 | DPP8 | dipeptidyl peptidase 8 [Source:HGNC Symbol;Acc:HGNC:16490] | 30104 | -0.348 | -0.7109 | No |
| 27 | DVL3 | dishevelled segment polarity protein 3 [Source:HGNC Symbol;Acc:HGNC:3087] | 30694 | -0.498 | -0.7151 | No |
| 28 | PTK7 | protein tyrosine kinase 7 (inactive) [Source:HGNC Symbol;Acc:HGNC:9618] | 32086 | -0.904 | -0.7314 | Yes |
| 29 | R3HDM2 | R3H domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29167] | 32203 | -0.939 | -0.7125 | Yes |
| 30 | REEP5 | receptor accessory protein 5 [Source:HGNC Symbol;Acc:HGNC:30077] | 32442 | -1.016 | -0.6950 | Yes |
| 31 | ADD1 | adducin 1 [Source:HGNC Symbol;Acc:HGNC:243] | 32741 | -1.110 | -0.6770 | Yes |
| 32 | SLC44A1 | solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798] | 32969 | -1.192 | -0.6551 | Yes |
| 33 | STN1 | STN1 subunit of CST complex [Source:HGNC Symbol;Acc:HGNC:26200] | 33173 | -1.272 | -0.6307 | Yes |
| 34 | MARK4 | microtubule affinity regulating kinase 4 [Source:HGNC Symbol;Acc:HGNC:13538] | 33550 | -1.412 | -0.6077 | Yes |
| 35 | DIP2B | disco interacting protein 2 homolog B [Source:HGNC Symbol;Acc:HGNC:29284] | 33829 | -1.535 | -0.5792 | Yes |
| 36 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 33994 | -1.617 | -0.5456 | Yes |
| 37 | MN1 | MN1 proto-oncogene, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:7180] | 34142 | -1.690 | -0.5099 | Yes |
| 38 | C5orf51 | chromosome 5 open reading frame 51 [Source:HGNC Symbol;Acc:HGNC:27750] | 34184 | -1.711 | -0.4708 | Yes |
| 39 | INKA2 | inka box actin regulator 2 [Source:HGNC Symbol;Acc:HGNC:28045] | 34188 | -1.715 | -0.4306 | Yes |
| 40 | DNMT3A | DNA methyltransferase 3 alpha [Source:HGNC Symbol;Acc:HGNC:2978] | 35043 | -2.132 | -0.4036 | Yes |
| 41 | HIF3A | hypoxia inducible factor 3 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15825] | 35213 | -2.256 | -0.3552 | Yes |
| 42 | ERF | ETS2 repressor factor [Source:HGNC Symbol;Acc:HGNC:3444] | 36402 | -3.353 | -0.3085 | Yes |
| 43 | ARRB1 | arrestin beta 1 [Source:HGNC Symbol;Acc:HGNC:711] | 36942 | -4.349 | -0.2209 | Yes |
| 44 | SEMA4G | semaphorin 4G [Source:HGNC Symbol;Acc:HGNC:10735] | 37039 | -4.748 | -0.1120 | Yes |
| 45 | SHCBP1L | SHC binding and spindle associated 1 like [Source:HGNC Symbol;Acc:HGNC:16788] | 37056 | -4.824 | 0.0009 | Yes |
