Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_BUB1B |
| Enrichment Score (ES) | -0.78822005 |
| Normalized Enrichment Score (NES) | -1.5488726 |
| Nominal p-value | 0.0013642565 |
| FDR q-value | 0.035081163 |
| FWER p-Value | 0.531 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2428 | 1.201 | -0.0501 | No |
| 2 | MRPL39 | mitochondrial ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:14027] | 4041 | 0.596 | -0.0860 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23509 | 0.000 | -0.6115 | No |
| 4 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 29129 | -0.207 | -0.7606 | No |
| 5 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 29461 | -0.290 | -0.7658 | No |
| 6 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29943 | -0.320 | -0.7746 | No |
| 7 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 30121 | -0.351 | -0.7749 | No |
| 8 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30615 | -0.478 | -0.7821 | Yes |
| 9 | CSE1L | chromosome segregation 1 like [Source:HGNC Symbol;Acc:HGNC:2431] | 30646 | -0.485 | -0.7767 | Yes |
| 10 | NUP205 | nucleoporin 205 [Source:HGNC Symbol;Acc:HGNC:18658] | 30906 | -0.559 | -0.7765 | Yes |
| 11 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 31169 | -0.633 | -0.7754 | Yes |
| 12 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31203 | -0.642 | -0.7681 | Yes |
| 13 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 31646 | -0.773 | -0.7701 | Yes |
| 14 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 32174 | -0.931 | -0.7724 | Yes |
| 15 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 32405 | -1.003 | -0.7657 | Yes |
| 16 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 32593 | -1.049 | -0.7573 | Yes |
| 17 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 32612 | -1.058 | -0.7442 | Yes |
| 18 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32872 | -1.155 | -0.7363 | Yes |
| 19 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 33082 | -1.236 | -0.7261 | Yes |
| 20 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 33141 | -1.259 | -0.7115 | Yes |
| 21 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 33668 | -1.457 | -0.7070 | Yes |
| 22 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 33841 | -1.541 | -0.6919 | Yes |
| 23 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 33926 | -1.576 | -0.6739 | Yes |
| 24 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34050 | -1.644 | -0.6561 | Yes |
| 25 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 34355 | -1.800 | -0.6412 | Yes |
| 26 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34493 | -1.883 | -0.6207 | Yes |
| 27 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34557 | -1.928 | -0.5977 | Yes |
| 28 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34589 | -1.943 | -0.5736 | Yes |
| 29 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34776 | -1.960 | -0.5534 | Yes |
| 30 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 34827 | -1.996 | -0.5291 | Yes |
| 31 | CEP55 | centrosomal protein 55 [Source:HGNC Symbol;Acc:HGNC:1161] | 34833 | -1.999 | -0.5036 | Yes |
| 32 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 34869 | -2.020 | -0.4786 | Yes |
| 33 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 34903 | -2.041 | -0.4533 | Yes |
| 34 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34967 | -2.085 | -0.4282 | Yes |
| 35 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35009 | -2.109 | -0.4023 | Yes |
| 36 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35057 | -2.142 | -0.3760 | Yes |
| 37 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35109 | -2.175 | -0.3495 | Yes |
| 38 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 35118 | -2.180 | -0.3217 | Yes |
| 39 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 35155 | -2.211 | -0.2943 | Yes |
| 40 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35199 | -2.244 | -0.2666 | Yes |
| 41 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 35206 | -2.250 | -0.2379 | Yes |
| 42 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 35269 | -2.283 | -0.2103 | Yes |
| 43 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 35551 | -2.485 | -0.1860 | Yes |
| 44 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 35689 | -2.604 | -0.1562 | Yes |
| 45 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35737 | -2.641 | -0.1236 | Yes |
| 46 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 35760 | -2.660 | -0.0900 | Yes |
| 47 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36035 | -2.919 | -0.0599 | Yes |
| 48 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36132 | -3.020 | -0.0238 | Yes |
| 49 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36724 | -3.863 | 0.0099 | Yes |
