Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_HMMR |
| Enrichment Score (ES) | -0.8271619 |
| Normalized Enrichment Score (NES) | -1.6261778 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.013556106 |
| FWER p-Value | 0.088 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3538 | 0.752 | -0.0862 | No |
| 2 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23509 | 0.000 | -0.6253 | No |
| 3 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28769 | -0.115 | -0.7659 | No |
| 4 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 29461 | -0.290 | -0.7809 | No |
| 5 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30083 | -0.340 | -0.7935 | No |
| 6 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 30121 | -0.351 | -0.7901 | No |
| 7 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30615 | -0.478 | -0.7975 | No |
| 8 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 31169 | -0.633 | -0.8047 | No |
| 9 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 31198 | -0.641 | -0.7975 | No |
| 10 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31203 | -0.642 | -0.7897 | No |
| 11 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 32593 | -1.049 | -0.8142 | Yes |
| 12 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 32612 | -1.058 | -0.8016 | Yes |
| 13 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32872 | -1.155 | -0.7943 | Yes |
| 14 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 33403 | -1.341 | -0.7921 | Yes |
| 15 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 33583 | -1.426 | -0.7793 | Yes |
| 16 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 33668 | -1.457 | -0.7636 | Yes |
| 17 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33695 | -1.469 | -0.7461 | Yes |
| 18 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 33792 | -1.517 | -0.7299 | Yes |
| 19 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 33841 | -1.541 | -0.7122 | Yes |
| 20 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34050 | -1.644 | -0.6975 | Yes |
| 21 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34106 | -1.671 | -0.6783 | Yes |
| 22 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34241 | -1.737 | -0.6605 | Yes |
| 23 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34281 | -1.756 | -0.6399 | Yes |
| 24 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 34458 | -1.861 | -0.6216 | Yes |
| 25 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34493 | -1.883 | -0.5993 | Yes |
| 26 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34557 | -1.928 | -0.5772 | Yes |
| 27 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 34903 | -2.041 | -0.5612 | Yes |
| 28 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34967 | -2.085 | -0.5372 | Yes |
| 29 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35009 | -2.109 | -0.5122 | Yes |
| 30 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35034 | -2.123 | -0.4867 | Yes |
| 31 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35057 | -2.142 | -0.4608 | Yes |
| 32 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35073 | -2.150 | -0.4346 | Yes |
| 33 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35109 | -2.175 | -0.4087 | Yes |
| 34 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 35118 | -2.180 | -0.3820 | Yes |
| 35 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35199 | -2.244 | -0.3564 | Yes |
| 36 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 35206 | -2.250 | -0.3288 | Yes |
| 37 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 35269 | -2.283 | -0.3022 | Yes |
| 38 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 35334 | -2.329 | -0.2752 | Yes |
| 39 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35670 | -2.585 | -0.2523 | Yes |
| 40 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 35689 | -2.604 | -0.2206 | Yes |
| 41 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35737 | -2.641 | -0.1893 | Yes |
| 42 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 35760 | -2.660 | -0.1570 | Yes |
| 43 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36035 | -2.919 | -0.1283 | Yes |
| 44 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36042 | -2.928 | -0.0923 | Yes |
| 45 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36044 | -2.930 | -0.0561 | Yes |
| 46 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36073 | -2.962 | -0.0203 | Yes |
| 47 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36724 | -3.863 | 0.0099 | Yes |
