Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_RRM1 |
| Enrichment Score (ES) | -0.7558395 |
| Normalized Enrichment Score (NES) | -1.6133841 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.015391686 |
| FWER p-Value | 0.13 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2428 | 1.201 | -0.0566 | No |
| 2 | USP14 | ubiquitin specific peptidase 14 [Source:HGNC Symbol;Acc:HGNC:12612] | 2746 | 1.048 | -0.0574 | No |
| 3 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 2847 | 1.004 | -0.0526 | No |
| 4 | PTGES3 | prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049] | 2963 | 0.947 | -0.0486 | No |
| 5 | CCT6A | chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620] | 3075 | 0.914 | -0.0448 | No |
| 6 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3155 | 0.884 | -0.0403 | No |
| 7 | PSMD14 | proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889] | 3193 | 0.870 | -0.0348 | No |
| 8 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3538 | 0.752 | -0.0385 | No |
| 9 | NUP37 | nucleoporin 37 [Source:HGNC Symbol;Acc:HGNC:29929] | 4085 | 0.581 | -0.0489 | No |
| 10 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 4465 | 0.480 | -0.0556 | No |
| 11 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 4891 | 0.368 | -0.0643 | No |
| 12 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5335 | 0.255 | -0.0744 | No |
| 13 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 5577 | 0.200 | -0.0794 | No |
| 14 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 5699 | 0.167 | -0.0814 | No |
| 15 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 6196 | 0.045 | -0.0945 | No |
| 16 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 15908 | 0.000 | -0.3569 | No |
| 17 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23509 | 0.000 | -0.5623 | No |
| 18 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28769 | -0.115 | -0.7036 | No |
| 19 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 28920 | -0.154 | -0.7065 | No |
| 20 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 29129 | -0.207 | -0.7106 | No |
| 21 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30083 | -0.340 | -0.7338 | No |
| 22 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 30110 | -0.349 | -0.7319 | No |
| 23 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 30121 | -0.351 | -0.7295 | No |
| 24 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 30231 | -0.378 | -0.7296 | No |
| 25 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 30279 | -0.388 | -0.7280 | No |
| 26 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30615 | -0.478 | -0.7335 | No |
| 27 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 31195 | -0.639 | -0.7444 | No |
| 28 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 31198 | -0.641 | -0.7396 | No |
| 29 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31203 | -0.642 | -0.7349 | No |
| 30 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31441 | -0.711 | -0.7360 | No |
| 31 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 32174 | -0.931 | -0.7489 | Yes |
| 32 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32433 | -1.015 | -0.7483 | Yes |
| 33 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 32593 | -1.049 | -0.7447 | Yes |
| 34 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32703 | -1.097 | -0.7395 | Yes |
| 35 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32730 | -1.105 | -0.7319 | Yes |
| 36 | FH | fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700] | 32850 | -1.147 | -0.7266 | Yes |
| 37 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32872 | -1.155 | -0.7185 | Yes |
| 38 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 33082 | -1.236 | -0.7149 | Yes |
| 39 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 33141 | -1.259 | -0.7071 | Yes |
| 40 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 33403 | -1.341 | -0.7041 | Yes |
| 41 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 33583 | -1.426 | -0.6983 | Yes |
| 42 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 33668 | -1.457 | -0.6897 | Yes |
| 43 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33695 | -1.469 | -0.6794 | Yes |
| 44 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 33792 | -1.517 | -0.6707 | Yes |
| 45 | CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906] | 33837 | -1.539 | -0.6604 | Yes |
| 46 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 33841 | -1.541 | -0.6489 | Yes |
| 47 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 33849 | -1.543 | -0.6376 | Yes |
| 48 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 33905 | -1.561 | -0.6274 | Yes |
| 49 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34050 | -1.644 | -0.6190 | Yes |
| 50 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34106 | -1.671 | -0.6080 | Yes |
| 51 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34241 | -1.737 | -0.5987 | Yes |
| 52 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34281 | -1.756 | -0.5866 | Yes |
| 53 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34472 | -1.873 | -0.5777 | Yes |
| 54 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34493 | -1.883 | -0.5642 | Yes |
| 55 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34557 | -1.928 | -0.5515 | Yes |
| 56 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34589 | -1.943 | -0.5378 | Yes |
| 57 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34776 | -1.960 | -0.5282 | Yes |
| 58 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 34827 | -1.996 | -0.5147 | Yes |
| 59 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 34869 | -2.020 | -0.5007 | Yes |
| 60 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 34903 | -2.041 | -0.4863 | Yes |
| 61 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34967 | -2.085 | -0.4724 | Yes |
| 62 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35009 | -2.109 | -0.4578 | Yes |
| 63 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35024 | -2.115 | -0.4424 | Yes |
| 64 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35034 | -2.123 | -0.4268 | Yes |
| 65 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35057 | -2.142 | -0.4114 | Yes |
| 66 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35073 | -2.150 | -0.3957 | Yes |
| 67 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35074 | -2.151 | -0.3796 | Yes |
| 68 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35109 | -2.175 | -0.3643 | Yes |
| 69 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 35118 | -2.180 | -0.3482 | Yes |
| 70 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35150 | -2.203 | -0.3326 | Yes |
| 71 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35199 | -2.244 | -0.3172 | Yes |
| 72 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 35206 | -2.250 | -0.3005 | Yes |
| 73 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 35334 | -2.329 | -0.2865 | Yes |
| 74 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35642 | -2.564 | -0.2757 | Yes |
| 75 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35670 | -2.585 | -0.2571 | Yes |
| 76 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 35689 | -2.604 | -0.2381 | Yes |
| 77 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35737 | -2.641 | -0.2197 | Yes |
| 78 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 35760 | -2.660 | -0.2004 | Yes |
| 79 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35972 | -2.829 | -0.1850 | Yes |
| 80 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36035 | -2.919 | -0.1648 | Yes |
| 81 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36042 | -2.928 | -0.1431 | Yes |
| 82 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36044 | -2.930 | -0.1213 | Yes |
| 83 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36073 | -2.962 | -0.0999 | Yes |
| 84 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 36132 | -3.020 | -0.0789 | Yes |
| 85 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36312 | -3.201 | -0.0598 | Yes |
| 86 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36482 | -3.462 | -0.0385 | Yes |
| 87 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36496 | -3.487 | -0.0128 | Yes |
| 88 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36724 | -3.863 | 0.0099 | Yes |
