Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_SMC4L1 |
| Enrichment Score (ES) | -0.7614179 |
| Normalized Enrichment Score (NES) | -1.6140723 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.017464474 |
| FWER p-Value | 0.129 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GAR1 | GAR1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14264] | 2165 | 1.364 | -0.0477 | No |
| 2 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 2296 | 1.276 | -0.0410 | No |
| 3 | EIF2S1 | eukaryotic translation initiation factor 2 subunit alpha [Source:HGNC Symbol;Acc:HGNC:3265] | 2847 | 1.004 | -0.0479 | No |
| 4 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3155 | 0.884 | -0.0492 | No |
| 5 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3538 | 0.752 | -0.0536 | No |
| 6 | SRSF1 | serine and arginine rich splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:10780] | 3697 | 0.690 | -0.0524 | No |
| 7 | NUP153 | nucleoporin 153 [Source:HGNC Symbol;Acc:HGNC:8062] | 4740 | 0.404 | -0.0773 | No |
| 8 | SNRPG | small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163] | 4891 | 0.368 | -0.0784 | No |
| 9 | METAP2 | methionyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:16672] | 5335 | 0.255 | -0.0884 | No |
| 10 | MRPL35 | mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:14489] | 5577 | 0.200 | -0.0933 | No |
| 11 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 5699 | 0.167 | -0.0952 | No |
| 12 | PCCB | propionyl-CoA carboxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8654] | 6196 | 0.045 | -0.1083 | No |
| 13 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23509 | 0.000 | -0.5761 | No |
| 14 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28769 | -0.115 | -0.7173 | No |
| 15 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 28920 | -0.154 | -0.7201 | No |
| 16 | ANP32B | acidic nuclear phosphoprotein 32 family member B [Source:HGNC Symbol;Acc:HGNC:16677] | 29234 | -0.229 | -0.7268 | No |
| 17 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30083 | -0.340 | -0.7470 | No |
| 18 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 30110 | -0.349 | -0.7449 | No |
| 19 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 30121 | -0.351 | -0.7424 | No |
| 20 | SERBP1 | SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17860] | 30231 | -0.378 | -0.7423 | No |
| 21 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 30279 | -0.388 | -0.7405 | No |
| 22 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30615 | -0.478 | -0.7458 | No |
| 23 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 31195 | -0.639 | -0.7563 | Yes |
| 24 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 31198 | -0.641 | -0.7513 | Yes |
| 25 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31203 | -0.642 | -0.7463 | Yes |
| 26 | COPS3 | COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239] | 31312 | -0.673 | -0.7439 | Yes |
| 27 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31441 | -0.711 | -0.7417 | Yes |
| 28 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 31999 | -0.874 | -0.7498 | Yes |
| 29 | ZWILCH | zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468] | 32069 | -0.899 | -0.7445 | Yes |
| 30 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 32174 | -0.931 | -0.7400 | Yes |
| 31 | HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13729] | 32231 | -0.948 | -0.7339 | Yes |
| 32 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 32433 | -1.015 | -0.7313 | Yes |
| 33 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32703 | -1.097 | -0.7299 | Yes |
| 34 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 32730 | -1.105 | -0.7218 | Yes |
| 35 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 32870 | -1.154 | -0.7164 | Yes |
| 36 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32872 | -1.155 | -0.7072 | Yes |
| 37 | EXOSC8 | exosome component 8 [Source:HGNC Symbol;Acc:HGNC:17035] | 32920 | -1.171 | -0.6992 | Yes |
| 38 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 33141 | -1.259 | -0.6952 | Yes |
| 39 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 33358 | -1.317 | -0.6905 | Yes |
| 40 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 33583 | -1.426 | -0.6853 | Yes |
| 41 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 33668 | -1.457 | -0.6760 | Yes |
| 42 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 33784 | -1.513 | -0.6671 | Yes |
| 43 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 33792 | -1.517 | -0.6552 | Yes |
| 44 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 33841 | -1.541 | -0.6442 | Yes |
| 45 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 33849 | -1.543 | -0.6322 | Yes |
| 46 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 33905 | -1.561 | -0.6213 | Yes |
| 47 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34050 | -1.644 | -0.6121 | Yes |
| 48 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34106 | -1.671 | -0.6003 | Yes |
| 49 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 34241 | -1.737 | -0.5901 | Yes |
| 50 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34281 | -1.756 | -0.5773 | Yes |
| 51 | DEK | DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768] | 34341 | -1.793 | -0.5646 | Yes |
| 52 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34472 | -1.873 | -0.5532 | Yes |
| 53 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34493 | -1.883 | -0.5388 | Yes |
| 54 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34557 | -1.928 | -0.5252 | Yes |
| 55 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34589 | -1.943 | -0.5106 | Yes |
| 56 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34776 | -1.960 | -0.5001 | Yes |
| 57 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 34869 | -2.020 | -0.4865 | Yes |
| 58 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 34903 | -2.041 | -0.4712 | Yes |
| 59 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 34967 | -2.085 | -0.4563 | Yes |
| 60 | CKAP2 | cytoskeleton associated protein 2 [Source:HGNC Symbol;Acc:HGNC:1990] | 34988 | -2.096 | -0.4402 | Yes |
| 61 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35009 | -2.109 | -0.4240 | Yes |
| 62 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35024 | -2.115 | -0.4076 | Yes |
| 63 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35034 | -2.123 | -0.3910 | Yes |
| 64 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35057 | -2.142 | -0.3746 | Yes |
| 65 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35073 | -2.150 | -0.3579 | Yes |
| 66 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35074 | -2.151 | -0.3408 | Yes |
| 67 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35109 | -2.175 | -0.3245 | Yes |
| 68 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35150 | -2.203 | -0.3081 | Yes |
| 69 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35199 | -2.244 | -0.2915 | Yes |
| 70 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 35206 | -2.250 | -0.2738 | Yes |
| 71 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 35334 | -2.329 | -0.2588 | Yes |
| 72 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 35634 | -2.552 | -0.2466 | Yes |
| 73 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35642 | -2.564 | -0.2264 | Yes |
| 74 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 35670 | -2.585 | -0.2066 | Yes |
| 75 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 35737 | -2.641 | -0.1874 | Yes |
| 76 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 35784 | -2.687 | -0.1673 | Yes |
| 77 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 35972 | -2.829 | -0.1499 | Yes |
| 78 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36035 | -2.919 | -0.1284 | Yes |
| 79 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36042 | -2.928 | -0.1053 | Yes |
| 80 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36073 | -2.962 | -0.0826 | Yes |
| 81 | FBXO5 | F-box protein 5 [Source:HGNC Symbol;Acc:HGNC:13584] | 36148 | -3.036 | -0.0605 | Yes |
| 82 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 36482 | -3.462 | -0.0420 | Yes |
| 83 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36496 | -3.487 | -0.0147 | Yes |
| 84 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36724 | -3.863 | 0.0099 | Yes |
