Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | MODULE_107 |
| Enrichment Score (ES) | 0.60467154 |
| Normalized Enrichment Score (NES) | 1.4682602 |
| Nominal p-value | 0.009803922 |
| FDR q-value | 0.32538506 |
| FWER p-Value | 0.987 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 66 | 4.648 | 0.0782 | Yes |
| 2 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 83 | 4.578 | 0.1565 | Yes |
| 3 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 136 | 4.283 | 0.2288 | Yes |
| 4 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 196 | 3.925 | 0.2947 | Yes |
| 5 | MMP14 | matrix metallopeptidase 14 [Source:HGNC Symbol;Acc:HGNC:7160] | 229 | 3.810 | 0.3594 | Yes |
| 6 | FAP | fibroblast activation protein alpha [Source:HGNC Symbol;Acc:HGNC:3590] | 425 | 3.158 | 0.4085 | Yes |
| 7 | ANPEP | alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500] | 510 | 2.991 | 0.4577 | Yes |
| 8 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 623 | 2.784 | 0.5026 | Yes |
| 9 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 985 | 2.230 | 0.5312 | Yes |
| 10 | MMP2 | matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166] | 1258 | 1.893 | 0.5564 | Yes |
| 11 | AEBP1 | AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303] | 1479 | 1.696 | 0.5796 | Yes |
| 12 | MST1 | macrophage stimulating 1 [Source:HGNC Symbol;Acc:HGNC:7380] | 2282 | 1.286 | 0.5801 | Yes |
| 13 | ADAM9 | ADAM metallopeptidase domain 9 [Source:HGNC Symbol;Acc:HGNC:216] | 3210 | 0.863 | 0.5699 | Yes |
| 14 | F10 | coagulation factor X [Source:HGNC Symbol;Acc:HGNC:3528] | 3242 | 0.854 | 0.5837 | Yes |
| 15 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 3569 | 0.742 | 0.5877 | Yes |
| 16 | CTSK | cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536] | 3787 | 0.684 | 0.5936 | Yes |
| 17 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 3806 | 0.673 | 0.6047 | Yes |
| 18 | CPN1 | carboxypeptidase N subunit 1 [Source:HGNC Symbol;Acc:HGNC:2312] | 4869 | 0.377 | 0.5825 | No |
| 19 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 5685 | 0.170 | 0.5634 | No |
| 20 | CTSD | cathepsin D [Source:HGNC Symbol;Acc:HGNC:2529] | 6064 | 0.080 | 0.5545 | No |
| 21 | WFDC2 | WAP four-disulfide core domain 2 [Source:HGNC Symbol;Acc:HGNC:15939] | 8247 | 0.000 | 0.4956 | No |
| 22 | FOLH1 | folate hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3788] | 9647 | 0.000 | 0.4578 | No |
| 23 | PLAT | plasminogen activator, tissue type [Source:HGNC Symbol;Acc:HGNC:9051] | 9976 | 0.000 | 0.4489 | No |
| 24 | APOC1 | apolipoprotein C1 [Source:HGNC Symbol;Acc:HGNC:607] | 10216 | 0.000 | 0.4424 | No |
| 25 | KLK10 | kallikrein related peptidase 10 [Source:HGNC Symbol;Acc:HGNC:6358] | 10539 | 0.000 | 0.4337 | No |
| 26 | TMPRSS2 | transmembrane serine protease 2 [Source:HGNC Symbol;Acc:HGNC:11876] | 11644 | 0.000 | 0.4039 | No |
| 27 | PROZ | protein Z, vitamin K dependent plasma glycoprotein [Source:HGNC Symbol;Acc:HGNC:9460] | 11687 | 0.000 | 0.4028 | No |
| 28 | PROC | protein C, inactivator of coagulation factors Va and VIIIa [Source:HGNC Symbol;Acc:HGNC:9451] | 11705 | 0.000 | 0.4023 | No |
| 29 | GZMA | granzyme A [Source:HGNC Symbol;Acc:HGNC:4708] | 12293 | 0.000 | 0.3865 | No |
| 30 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12295 | 0.000 | 0.3864 | No |
| 31 | GZMK | granzyme K [Source:HGNC Symbol;Acc:HGNC:4711] | 12297 | 0.000 | 0.3864 | No |
| 32 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12848 | 0.000 | 0.3716 | No |
| 33 | HTRA1 | HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476] | 15694 | 0.000 | 0.2947 | No |
| 34 | CFI | complement factor I [Source:HGNC Symbol;Acc:HGNC:5394] | 15772 | 0.000 | 0.2926 | No |
| 35 | CPM | carboxypeptidase M [Source:HGNC Symbol;Acc:HGNC:2311] | 15842 | 0.000 | 0.2907 | No |
| 36 | C2 | complement C2 [Source:HGNC Symbol;Acc:HGNC:1248] | 16107 | 0.000 | 0.2836 | No |
| 37 | F2 | coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535] | 16156 | 0.000 | 0.2823 | No |
| 38 | HP | haptoglobin [Source:HGNC Symbol;Acc:HGNC:5141] | 16199 | 0.000 | 0.2812 | No |
| 39 | F12 | coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530] | 16463 | 0.000 | 0.2741 | No |
| 40 | OLR1 | oxidized low density lipoprotein receptor 1 [Source:HGNC Symbol;Acc:HGNC:8133] | 16756 | 0.000 | 0.2662 | No |
| 41 | DPP4 | dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009] | 17984 | 0.000 | 0.2330 | No |
| 42 | BMP1 | bone morphogenetic protein 1 [Source:HGNC Symbol;Acc:HGNC:1067] | 19149 | 0.000 | 0.2016 | No |
| 43 | MMP7 | matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174] | 19172 | 0.000 | 0.2010 | No |
| 44 | MMP1 | matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] | 19175 | 0.000 | 0.2009 | No |
| 45 | MMP3 | matrix metallopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:7173] | 19179 | 0.000 | 0.2009 | No |
| 46 | PGC | progastricsin [Source:HGNC Symbol;Acc:HGNC:8890] | 20090 | 0.000 | 0.1763 | No |
| 47 | CPA3 | carboxypeptidase A3 [Source:HGNC Symbol;Acc:HGNC:2298] | 20570 | 0.000 | 0.1633 | No |
| 48 | CPB2 | carboxypeptidase B2 [Source:HGNC Symbol;Acc:HGNC:2300] | 20586 | 0.000 | 0.1629 | No |
| 49 | TPSAB1 | tryptase alpha/beta 1 [Source:HGNC Symbol;Acc:HGNC:12019] | 21206 | 0.000 | 0.1462 | No |
| 50 | CTSW | cathepsin W [Source:HGNC Symbol;Acc:HGNC:2546] | 22236 | 0.000 | 0.1184 | No |
| 51 | CTSL | cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537] | 22240 | 0.000 | 0.1183 | No |
| 52 | PRSS23 | serine protease 23 [Source:HGNC Symbol;Acc:HGNC:14370] | 22429 | 0.000 | 0.1132 | No |
| 53 | PRSS8 | serine protease 8 [Source:HGNC Symbol;Acc:HGNC:9491] | 22653 | 0.000 | 0.1072 | No |
| 54 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 24166 | 0.000 | 0.0664 | No |
| 55 | CELA3A | chymotrypsin like elastase 3A [Source:HGNC Symbol;Acc:HGNC:15944] | 24200 | 0.000 | 0.0655 | No |
| 56 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 24498 | 0.000 | 0.0574 | No |
| 57 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 24502 | 0.000 | 0.0574 | No |
| 58 | PLG | plasminogen [Source:HGNC Symbol;Acc:HGNC:9071] | 24797 | 0.000 | 0.0494 | No |
| 59 | KLK6 | kallikrein related peptidase 6 [Source:HGNC Symbol;Acc:HGNC:6367] | 25427 | 0.000 | 0.0324 | No |
| 60 | MMP10 | matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] | 25658 | 0.000 | 0.0262 | No |
| 61 | MMP12 | matrix metallopeptidase 12 [Source:HGNC Symbol;Acc:HGNC:7158] | 25660 | 0.000 | 0.0262 | No |
| 62 | MMP11 | matrix metallopeptidase 11 [Source:HGNC Symbol;Acc:HGNC:7157] | 25662 | 0.000 | 0.0262 | No |
| 63 | MMP15 | matrix metallopeptidase 15 [Source:HGNC Symbol;Acc:HGNC:7161] | 25667 | 0.000 | 0.0261 | No |
| 64 | ACY1 | aminoacylase 1 [Source:HGNC Symbol;Acc:HGNC:177] | 28681 | -0.087 | -0.0539 | No |
| 65 | PEPD | peptidase D [Source:HGNC Symbol;Acc:HGNC:8840] | 28911 | -0.151 | -0.0574 | No |
| 66 | HPN | hepsin [Source:HGNC Symbol;Acc:HGNC:5155] | 30488 | -0.443 | -0.0924 | No |
| 67 | XPNPEP1 | X-prolyl aminopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:12822] | 31359 | -0.689 | -0.1041 | No |
| 68 | ADAM8 | ADAM metallopeptidase domain 8 [Source:HGNC Symbol;Acc:HGNC:215] | 31367 | -0.692 | -0.0923 | No |
| 69 | CTSB | cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527] | 31379 | -0.697 | -0.0806 | No |
| 70 | CTSS | cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545] | 31600 | -0.765 | -0.0734 | No |
| 71 | CTSO | cathepsin O [Source:HGNC Symbol;Acc:HGNC:2542] | 32330 | -0.979 | -0.0763 | No |
| 72 | NAPSA | napsin A aspartic peptidase [Source:HGNC Symbol;Acc:HGNC:13395] | 32582 | -1.044 | -0.0651 | No |
| 73 | CAPN2 | calpain 2 [Source:HGNC Symbol;Acc:HGNC:1479] | 32773 | -1.120 | -0.0510 | No |
| 74 | C1R | complement C1r [Source:HGNC Symbol;Acc:HGNC:1246] | 33685 | -1.466 | -0.0503 | No |
| 75 | CTSE | cathepsin E [Source:HGNC Symbol;Acc:HGNC:2530] | 33965 | -1.599 | -0.0304 | No |
| 76 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 33995 | -1.617 | -0.0033 | No |
| 77 | LGMN | legumain [Source:HGNC Symbol;Acc:HGNC:9472] | 34985 | -2.094 | 0.0060 | No |
| 78 | PLAU | plasminogen activator, urokinase [Source:HGNC Symbol;Acc:HGNC:9052] | 36069 | -2.957 | 0.0276 | No |
