Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GOBP_ACUTE_PHASE_RESPONSE |
| Enrichment Score (ES) | 0.8815037 |
| Normalized Enrichment Score (NES) | 1.9327593 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0029429882 |
| FWER p-Value | 0.012 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 15 | 4.957 | 0.1360 | Yes |
| 2 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 18 | 4.941 | 0.2718 | Yes |
| 3 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 22 | 4.935 | 0.4075 | Yes |
| 4 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 32 | 4.887 | 0.5417 | Yes |
| 5 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 144 | 4.221 | 0.6548 | Yes |
| 6 | ASS1 | argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758] | 516 | 2.977 | 0.7267 | Yes |
| 7 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 921 | 2.252 | 0.7777 | Yes |
| 8 | IL6R | interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019] | 1956 | 1.388 | 0.7880 | Yes |
| 9 | SIGIRR | single Ig and TIR domain containing [Source:HGNC Symbol;Acc:HGNC:30575] | 2389 | 1.222 | 0.8099 | Yes |
| 10 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 2684 | 1.073 | 0.8315 | Yes |
| 11 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 2700 | 1.063 | 0.8604 | Yes |
| 12 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2910 | 0.974 | 0.8815 | Yes |
| 13 | F8 | coagulation factor VIII [Source:HGNC Symbol;Acc:HGNC:3546] | 3682 | 0.693 | 0.8797 | No |
| 14 | TNFRSF11A | TNF receptor superfamily member 11a [Source:HGNC Symbol;Acc:HGNC:11908] | 4471 | 0.479 | 0.8717 | No |
| 15 | FN1 | fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778] | 5177 | 0.291 | 0.8606 | No |
| 16 | APCS | amyloid P component, serum [Source:HGNC Symbol;Acc:HGNC:584] | 6721 | 0.000 | 0.8190 | No |
| 17 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7821 | 0.000 | 0.7893 | No |
| 18 | APOL2 | apolipoprotein L2 [Source:HGNC Symbol;Acc:HGNC:619] | 10141 | 0.000 | 0.7267 | No |
| 19 | TNFSF11 | TNF superfamily member 11 [Source:HGNC Symbol;Acc:HGNC:11926] | 12481 | 0.000 | 0.6636 | No |
| 20 | IL22 | interleukin 22 [Source:HGNC Symbol;Acc:HGNC:14900] | 13836 | 0.000 | 0.6270 | No |
| 21 | MBL2 | mannose binding lectin 2 [Source:HGNC Symbol;Acc:HGNC:6922] | 15597 | 0.000 | 0.5795 | No |
| 22 | CRP | C-reactive protein [Source:HGNC Symbol;Acc:HGNC:2367] | 15865 | 0.000 | 0.5723 | No |
| 23 | F2 | coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535] | 16156 | 0.000 | 0.5645 | No |
| 24 | HP | haptoglobin [Source:HGNC Symbol;Acc:HGNC:5141] | 16199 | 0.000 | 0.5633 | No |
| 25 | EPO | erythropoietin [Source:HGNC Symbol;Acc:HGNC:3415] | 16488 | 0.000 | 0.5556 | No |
| 26 | HFE | homeostatic iron regulator [Source:HGNC Symbol;Acc:HGNC:4886] | 17369 | 0.000 | 0.5318 | No |
| 27 | INS | insulin [Source:HGNC Symbol;Acc:HGNC:6081] | 17784 | 0.000 | 0.5206 | No |
| 28 | SERPINF2 | serpin family F member 2 [Source:HGNC Symbol;Acc:HGNC:9075] | 17811 | 0.000 | 0.5199 | No |
| 29 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 17822 | 0.000 | 0.5197 | No |
| 30 | SERPINA1 | serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941] | 17824 | 0.000 | 0.5196 | No |
| 31 | LBP | lipopolysaccharide binding protein [Source:HGNC Symbol;Acc:HGNC:6517] | 18559 | 0.000 | 0.4998 | No |
| 32 | ORM1 | orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498] | 18700 | 0.000 | 0.4960 | No |
| 33 | ORM2 | orosomucoid 2 [Source:HGNC Symbol;Acc:HGNC:8499] | 18701 | 0.000 | 0.4960 | No |
| 34 | MRGPRX1 | MAS related GPR family member X1 [Source:HGNC Symbol;Acc:HGNC:17962] | 19553 | 0.000 | 0.4731 | No |
| 35 | CNR1 | cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] | 20145 | 0.000 | 0.4571 | No |
| 36 | AHSG | alpha 2-HS glycoprotein [Source:HGNC Symbol;Acc:HGNC:349] | 20230 | 0.000 | 0.4549 | No |
| 37 | SAA4 | serum amyloid A4, constitutive [Source:HGNC Symbol;Acc:HGNC:10516] | 21877 | 0.000 | 0.4104 | No |
| 38 | SAA2 | serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514] | 21895 | 0.000 | 0.4100 | No |
| 39 | HAMP | hepcidin antimicrobial peptide [Source:HGNC Symbol;Acc:HGNC:15598] | 22064 | 0.000 | 0.4054 | No |
| 40 | REG3A | regenerating family member 3 alpha [Source:HGNC Symbol;Acc:HGNC:8601] | 23757 | 0.000 | 0.3598 | No |
| 41 | REG3G | regenerating family member 3 gamma [Source:HGNC Symbol;Acc:HGNC:29595] | 23761 | 0.000 | 0.3597 | No |
| 42 | UGT1A1 | UDP glucuronosyltransferase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:12530] | 24009 | 0.000 | 0.3530 | No |
| 43 | ITIH4 | inter-alpha-trypsin inhibitor heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:6169] | 24306 | 0.000 | 0.3450 | No |
| 44 | PTGER3 | prostaglandin E receptor 3 [Source:HGNC Symbol;Acc:HGNC:9595] | 24856 | 0.000 | 0.3302 | No |
| 45 | TFR2 | transferrin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11762] | 25611 | 0.000 | 0.3098 | No |
| 46 | EDNRB | endothelin receptor type B [Source:HGNC Symbol;Acc:HGNC:3180] | 26878 | 0.000 | 0.2757 | No |
