Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOBP_HOMOLOGOUS_CHROMOSOME_SEGREGATION |
| Enrichment Score (ES) | -0.79918104 |
| Normalized Enrichment Score (NES) | -1.6327238 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06952393 |
| FWER p-Value | 0.602 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RNF212 | ring finger protein 212 [Source:HGNC Symbol;Acc:HGNC:27729] | 2958 | 0.948 | -0.0602 | No |
| 2 | BRIP1 | BRCA1 interacting protein C-terminal helicase 1 [Source:HGNC Symbol;Acc:HGNC:20473] | 4461 | 0.481 | -0.0908 | No |
| 3 | MSH4 | mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:7327] | 4738 | 0.405 | -0.0899 | No |
| 4 | CENPC | centromere protein C [Source:HGNC Symbol;Acc:HGNC:1854] | 4901 | 0.367 | -0.0866 | No |
| 5 | BAG6 | BAG cochaperone 6 [Source:HGNC Symbol;Acc:HGNC:13919] | 5175 | 0.291 | -0.0880 | No |
| 6 | ANKRD31 | ankyrin repeat domain 31 [Source:HGNC Symbol;Acc:HGNC:26853] | 7762 | 0.000 | -0.1578 | No |
| 7 | STAG3 | stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356] | 7925 | 0.000 | -0.1622 | No |
| 8 | PTTG2 | pituitary tumor-transforming 2 [Source:HGNC Symbol;Acc:HGNC:9691] | 7994 | 0.000 | -0.1640 | No |
| 9 | RAD21L1 | RAD21 cohesin complex component like 1 [Source:HGNC Symbol;Acc:HGNC:16271] | 8154 | 0.000 | -0.1683 | No |
| 10 | C1orf146 | chromosome 1 open reading frame 146 [Source:HGNC Symbol;Acc:HGNC:24032] | 10193 | 0.000 | -0.2233 | No |
| 11 | MEIOC | meiosis specific with coiled-coil domain [Source:HGNC Symbol;Acc:HGNC:26670] | 10853 | 0.000 | -0.2411 | No |
| 12 | RNF212B | ring finger protein 212B [Source:HGNC Symbol;Acc:HGNC:20438] | 11720 | 0.000 | -0.2645 | No |
| 13 | IHO1 | interactor of HORMAD1 1 [Source:HGNC Symbol;Acc:HGNC:27945] | 12832 | 0.000 | -0.2945 | No |
| 14 | MEIKIN | meiotic kinetochore factor [Source:HGNC Symbol;Acc:HGNC:51253] | 12894 | 0.000 | -0.2962 | No |
| 15 | TERB1 | telomere repeat binding bouquet formation protein 1 [Source:HGNC Symbol;Acc:HGNC:26675] | 13190 | 0.000 | -0.3041 | No |
| 16 | TERB2 | telomere repeat binding bouquet formation protein 2 [Source:HGNC Symbol;Acc:HGNC:28520] | 13191 | 0.000 | -0.3041 | No |
| 17 | REC8 | REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879] | 13763 | 0.000 | -0.3196 | No |
| 18 | TEX11 | testis expressed 11 [Source:HGNC Symbol;Acc:HGNC:11733] | 15362 | 0.000 | -0.3627 | No |
| 19 | TEX12 | testis expressed 12 [Source:HGNC Symbol;Acc:HGNC:11734] | 15363 | 0.000 | -0.3627 | No |
| 20 | TEX15 | testis expressed 15, meiosis and synapsis associated [Source:HGNC Symbol;Acc:HGNC:11738] | 15364 | 0.000 | -0.3627 | No |
| 21 | MEI4 | meiotic double-stranded break formation protein 4 [Source:HGNC Symbol;Acc:HGNC:43638] | 16404 | 0.000 | -0.3908 | No |
| 22 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16924 | 0.000 | -0.4048 | No |
| 23 | SYCE3 | synaptonemal complex central element protein 3 [Source:HGNC Symbol;Acc:HGNC:35245] | 17011 | 0.000 | -0.4071 | No |
| 24 | SYCE1 | synaptonemal complex central element protein 1 [Source:HGNC Symbol;Acc:HGNC:28852] | 17012 | 0.000 | -0.4071 | No |
| 25 | SYCP2 | synaptonemal complex protein 2 [Source:HGNC Symbol;Acc:HGNC:11490] | 17894 | 0.000 | -0.4309 | No |
| 26 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17895 | 0.000 | -0.4309 | No |
| 27 | CCNB1IP1 | cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437] | 18364 | 0.000 | -0.4435 | No |
| 28 | PTTG3P | pituitary tumor-transforming 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:13422] | 18553 | 0.000 | -0.4486 | No |
| 29 | P3H4 | prolyl 3-hydroxylase family member 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:16946] | 18630 | 0.000 | -0.4507 | No |
| 30 | SPO11 | SPO11 initiator of meiotic double stranded breaks [Source:HGNC Symbol;Acc:HGNC:11250] | 19531 | 0.000 | -0.4750 | No |
| 31 | C14orf39 | chromosome 14 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:19849] | 19772 | 0.000 | -0.4815 | No |
| 32 | KASH5 | KASH domain containing 5 [Source:HGNC Symbol;Acc:HGNC:26520] | 20804 | 0.000 | -0.5093 | No |
| 33 | MAJIN | membrane anchored junction protein [Source:HGNC Symbol;Acc:HGNC:27441] | 22065 | 0.000 | -0.5433 | No |
| 34 | SPATA22 | spermatogenesis associated 22 [Source:HGNC Symbol;Acc:HGNC:30705] | 22212 | 0.000 | -0.5473 | No |
| 35 | FMN2 | formin 2 [Source:HGNC Symbol;Acc:HGNC:14074] | 24508 | 0.000 | -0.6092 | No |
| 36 | MAEL | maelstrom spermatogenic transposon silencer [Source:HGNC Symbol;Acc:HGNC:25929] | 24579 | 0.000 | -0.6111 | No |
| 37 | HORMAD1 | HORMA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25245] | 26621 | 0.000 | -0.6662 | No |
| 38 | SYCE1L | synaptonemal complex central element protein 1 like [Source:HGNC Symbol;Acc:HGNC:37236] | 27713 | 0.000 | -0.6957 | No |
| 39 | NDC1 | NDC1 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:25525] | 28787 | -0.120 | -0.7222 | No |
| 40 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28881 | -0.144 | -0.7217 | No |
| 41 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 30018 | -0.328 | -0.7456 | No |
| 42 | UBE2B | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | 30662 | -0.488 | -0.7528 | No |
| 43 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 31169 | -0.633 | -0.7534 | No |
| 44 | ZCWPW1 | zinc finger CW-type and PWWP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23486] | 32510 | -1.025 | -0.7683 | Yes |
| 45 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 32612 | -1.058 | -0.7491 | Yes |
| 46 | RAD21 | RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811] | 34467 | -1.871 | -0.7604 | Yes |
| 47 | SIRT7 | sirtuin 7 [Source:HGNC Symbol;Acc:HGNC:14935] | 34518 | -1.901 | -0.7223 | Yes |
| 48 | MLH3 | mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128] | 34852 | -2.013 | -0.6896 | Yes |
| 49 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 35101 | -2.164 | -0.6514 | Yes |
| 50 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 35220 | -2.260 | -0.6077 | Yes |
| 51 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35261 | -2.280 | -0.5615 | Yes |
| 52 | ATM | ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795] | 35674 | -2.588 | -0.5190 | Yes |
| 53 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 35738 | -2.643 | -0.4659 | Yes |
| 54 | AGO4 | argonaute RISC component 4 [Source:HGNC Symbol;Acc:HGNC:18424] | 35978 | -2.837 | -0.4135 | Yes |
| 55 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36374 | -3.300 | -0.3558 | Yes |
| 56 | FANCD2 | FA complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585] | 36401 | -3.353 | -0.2870 | Yes |
| 57 | PRDM9 | PR/SET domain 9 [Source:HGNC Symbol;Acc:HGNC:13994] | 36421 | -3.374 | -0.2175 | Yes |
| 58 | MEIOB | meiosis specific with OB-fold [Source:HGNC Symbol;Acc:HGNC:28569] | 36489 | -3.473 | -0.1473 | Yes |
| 59 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36717 | -3.856 | -0.0735 | Yes |
| 60 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 36811 | -4.029 | 0.0075 | Yes |
