Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | GOMF_CHEMOKINE_RECEPTOR_BINDING |
| Enrichment Score (ES) | 0.84715176 |
| Normalized Enrichment Score (NES) | 2.0297208 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.074806E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 31 | 4.888 | 0.1948 | Yes |
| 2 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 58 | 4.730 | 0.3834 | Yes |
| 3 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 318 | 3.407 | 0.5128 | Yes |
| 4 | CXCL14 | C-X-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10640] | 397 | 3.220 | 0.6395 | Yes |
| 5 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.7368 | Yes |
| 6 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 2206 | 1.337 | 0.7497 | Yes |
| 7 | NARS1 | asparaginyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7643] | 2230 | 1.324 | 0.8020 | Yes |
| 8 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 2402 | 1.214 | 0.8460 | Yes |
| 9 | CKLF | chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253] | 3498 | 0.768 | 0.8472 | Yes |
| 10 | CNIH4 | cornichon family AMPA receptor auxiliary protein 4 [Source:HGNC Symbol;Acc:HGNC:25013] | 4653 | 0.428 | 0.8331 | No |
| 11 | YARS1 | tyrosyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12840] | 4899 | 0.367 | 0.8412 | No |
| 12 | CCL14 | C-C motif chemokine ligand 14 [Source:HGNC Symbol;Acc:HGNC:10612] | 6408 | 0.000 | 0.8005 | No |
| 13 | CCL13 | C-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10611] | 6409 | 0.000 | 0.8005 | No |
| 14 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6410 | 0.000 | 0.8005 | No |
| 15 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6430 | 0.000 | 0.8000 | No |
| 16 | CCL18 | C-C motif chemokine ligand 18 [Source:HGNC Symbol;Acc:HGNC:10616] | 6431 | 0.000 | 0.8000 | No |
| 17 | CCL17 | C-C motif chemokine ligand 17 [Source:HGNC Symbol;Acc:HGNC:10615] | 6433 | 0.000 | 0.7999 | No |
| 18 | CCL16 | C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614] | 6434 | 0.000 | 0.7999 | No |
| 19 | CCL15 | C-C motif chemokine ligand 15 [Source:HGNC Symbol;Acc:HGNC:10613] | 6436 | 0.000 | 0.7999 | No |
| 20 | CCL25 | C-C motif chemokine ligand 25 [Source:HGNC Symbol;Acc:HGNC:10624] | 6437 | 0.000 | 0.7999 | No |
| 21 | CCL24 | C-C motif chemokine ligand 24 [Source:HGNC Symbol;Acc:HGNC:10623] | 6438 | 0.000 | 0.7999 | No |
| 22 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6440 | 0.000 | 0.7999 | No |
| 23 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6441 | 0.000 | 0.7999 | No |
| 24 | CCL21 | C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620] | 6442 | 0.000 | 0.7999 | No |
| 25 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6444 | 0.000 | 0.7998 | No |
| 26 | CCL28 | C-C motif chemokine ligand 28 [Source:HGNC Symbol;Acc:HGNC:17700] | 6460 | 0.000 | 0.7994 | No |
| 27 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6462 | 0.000 | 0.7994 | No |
| 28 | CCL26 | C-C motif chemokine ligand 26 [Source:HGNC Symbol;Acc:HGNC:10625] | 6464 | 0.000 | 0.7994 | No |
| 29 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7252 | 0.000 | 0.7781 | No |
| 30 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8852 | 0.000 | 0.7349 | No |
| 31 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10819 | 0.000 | 0.6818 | No |
| 32 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11051 | 0.000 | 0.6756 | No |
| 33 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11218 | 0.000 | 0.6711 | No |
| 34 | S100A14 | S100 calcium binding protein A14 [Source:HGNC Symbol;Acc:HGNC:18901] | 11807 | 0.000 | 0.6552 | No |
| 35 | MSMP | microseminoprotein, prostate associated [Source:HGNC Symbol;Acc:HGNC:29663] | 12467 | 0.000 | 0.6374 | No |
| 36 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14849 | 0.000 | 0.5731 | No |
| 37 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14851 | 0.000 | 0.5731 | No |
| 38 | XCL2 | X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646] | 15860 | 0.000 | 0.5459 | No |
| 39 | XCL1 | X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10645] | 15862 | 0.000 | 0.5458 | No |
| 40 | C5 | complement C5 [Source:HGNC Symbol;Acc:HGNC:1331] | 16109 | 0.000 | 0.5392 | No |
| 41 | CXCL13 | C-X-C motif chemokine ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] | 18946 | 0.000 | 0.4626 | No |
| 42 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18950 | 0.000 | 0.4625 | No |
| 43 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18985 | 0.000 | 0.4616 | No |
| 44 | CXCL12 | C-X-C motif chemokine ligand 12 [Source:HGNC Symbol;Acc:HGNC:10672] | 18986 | 0.000 | 0.4616 | No |
| 45 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19524 | 0.000 | 0.4471 | No |
| 46 | CXCL9 | C-X-C motif chemokine ligand 9 [Source:HGNC Symbol;Acc:HGNC:7098] | 19526 | 0.000 | 0.4471 | No |
| 47 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19528 | 0.000 | 0.4470 | No |
| 48 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19537 | 0.000 | 0.4468 | No |
| 49 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19539 | 0.000 | 0.4468 | No |
| 50 | CXCL5 | C-X-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10642] | 19541 | 0.000 | 0.4468 | No |
| 51 | PF4 | platelet factor 4 [Source:HGNC Symbol;Acc:HGNC:8861] | 20084 | 0.000 | 0.4321 | No |
| 52 | DEFB1 | defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766] | 20561 | 0.000 | 0.4193 | No |
| 53 | PF4V1 | platelet factor 4 variant 1 [Source:HGNC Symbol;Acc:HGNC:8862] | 24518 | 0.000 | 0.3124 | No |
| 54 | TFF2 | trefoil factor 2 [Source:HGNC Symbol;Acc:HGNC:11756] | 25452 | 0.000 | 0.2872 | No |
| 55 | DEFB109B | defensin beta 109B [Source:HGNC Symbol;Acc:HGNC:33469] | 25891 | 0.000 | 0.2754 | No |
| 56 | DEFB130A | defensin beta 130A [Source:HGNC Symbol;Acc:HGNC:18107] | 26997 | 0.000 | 0.2455 | No |
| 57 | DEFB130B | defensin beta 130B [Source:HGNC Symbol;Acc:HGNC:39814] | 26999 | 0.000 | 0.2455 | No |
| 58 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27950 | 0.000 | 0.2199 | No |
| 59 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27952 | 0.000 | 0.2198 | No |
| 60 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 27959 | 0.000 | 0.2197 | No |
| 61 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27961 | 0.000 | 0.2196 | No |
| 62 | CCL1 | C-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10609] | 27962 | 0.000 | 0.2196 | No |
| 63 | DEFB103A | defensin beta 103A [Source:HGNC Symbol;Acc:HGNC:15967] | 28005 | 0.000 | 0.2185 | No |
| 64 | DEFB103B | defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702] | 28007 | 0.000 | 0.2185 | No |
| 65 | DEFB106B | defensin beta 106B [Source:HGNC Symbol;Acc:HGNC:28879] | 28061 | 0.000 | 0.2170 | No |
| 66 | DEFB106A | defensin beta 106A [Source:HGNC Symbol;Acc:HGNC:18088] | 28068 | 0.000 | 0.2169 | No |
| 67 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 28687 | -0.089 | 0.2037 | No |
| 68 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 30967 | -0.580 | 0.1654 | No |
