Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOMF_NEUROPEPTIDE_BINDING |
| Enrichment Score (ES) | -0.9661293 |
| Normalized Enrichment Score (NES) | -1.6934484 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01258838 |
| FWER p-Value | 0.093 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SSTR2 | somatostatin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11331] | 6292 | 0.018 | -0.1635 | No |
| 2 | OPRD1 | opioid receptor delta 1 [Source:HGNC Symbol;Acc:HGNC:8153] | 9151 | 0.000 | -0.2406 | No |
| 3 | OPRM1 | opioid receptor mu 1 [Source:HGNC Symbol;Acc:HGNC:8156] | 9242 | 0.000 | -0.2431 | No |
| 4 | OPRL1 | opioid related nociceptin receptor 1 [Source:HGNC Symbol;Acc:HGNC:8155] | 9247 | 0.000 | -0.2432 | No |
| 5 | OPRK1 | opioid receptor kappa 1 [Source:HGNC Symbol;Acc:HGNC:8154] | 9259 | 0.000 | -0.2435 | No |
| 6 | GPR1 | G protein-coupled receptor 1 [Source:HGNC Symbol;Acc:HGNC:4463] | 9472 | 0.000 | -0.2492 | No |
| 7 | GRPR | gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609] | 10072 | 0.000 | -0.2654 | No |
| 8 | MCHR1 | melanin concentrating hormone receptor 1 [Source:HGNC Symbol;Acc:HGNC:4479] | 11688 | 0.000 | -0.3089 | No |
| 9 | SSTR1 | somatostatin receptor 1 [Source:HGNC Symbol;Acc:HGNC:11330] | 11730 | 0.000 | -0.3100 | No |
| 10 | SSTR3 | somatostatin receptor 3 [Source:HGNC Symbol;Acc:HGNC:11332] | 11731 | 0.000 | -0.3100 | No |
| 11 | SSTR4 | somatostatin receptor 4 [Source:HGNC Symbol;Acc:HGNC:11333] | 11732 | 0.000 | -0.3100 | No |
| 12 | SSTR5 | somatostatin receptor 5 [Source:HGNC Symbol;Acc:HGNC:11334] | 11733 | 0.000 | -0.3100 | No |
| 13 | MC4R | melanocortin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6932] | 15669 | 0.000 | -0.4162 | No |
| 14 | MC3R | melanocortin 3 receptor [Source:HGNC Symbol;Acc:HGNC:6931] | 15675 | 0.000 | -0.4163 | No |
| 15 | GPR149 | G protein-coupled receptor 149 [Source:HGNC Symbol;Acc:HGNC:23627] | 16472 | 0.000 | -0.4378 | No |
| 16 | GPR37 | G protein-coupled receptor 37 [Source:HGNC Symbol;Acc:HGNC:4494] | 17525 | 0.000 | -0.4662 | No |
| 17 | NPBWR1 | neuropeptides B and W receptor 1 [Source:HGNC Symbol;Acc:HGNC:4522] | 18096 | 0.000 | -0.4816 | No |
| 18 | NPBWR2 | neuropeptides B and W receptor 2 [Source:HGNC Symbol;Acc:HGNC:4530] | 18099 | 0.000 | -0.4816 | No |
| 19 | MRGPRX2 | MAS related GPR family member X2 [Source:HGNC Symbol;Acc:HGNC:17983] | 19551 | 0.000 | -0.5208 | No |
| 20 | PTGDR2 | prostaglandin D2 receptor 2 [Source:HGNC Symbol;Acc:HGNC:4502] | 25055 | 0.000 | -0.6692 | No |
| 21 | GALR2 | galanin receptor 2 [Source:HGNC Symbol;Acc:HGNC:4133] | 25184 | 0.000 | -0.6727 | No |
| 22 | GALR1 | galanin receptor 1 [Source:HGNC Symbol;Acc:HGNC:4132] | 25187 | 0.000 | -0.6727 | No |
| 23 | NMUR2 | neuromedin U receptor 2 [Source:HGNC Symbol;Acc:HGNC:16454] | 27729 | 0.000 | -0.7413 | Yes |
| 24 | NMUR1 | neuromedin U receptor 1 [Source:HGNC Symbol;Acc:HGNC:4518] | 27730 | 0.000 | -0.7413 | Yes |
| 25 | SORL1 | sortilin related receptor 1 [Source:HGNC Symbol;Acc:HGNC:11185] | 36065 | -2.952 | 0.0277 | Yes |
