Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | -0.7898944 |
| Normalized Enrichment Score (NES) | -1.6289277 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07272734 |
| FWER p-Value | 0.654 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GRIA1 | glutamate ionotropic receptor AMPA type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4571] | 9337 | 0.000 | -0.2522 | No |
| 2 | GRIA3 | glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573] | 9348 | 0.000 | -0.2524 | No |
| 3 | GRID2 | glutamate ionotropic receptor delta type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4576] | 9367 | 0.000 | -0.2529 | No |
| 4 | GRID1 | glutamate ionotropic receptor delta type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4575] | 9369 | 0.000 | -0.2529 | No |
| 5 | GRM1 | glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593] | 10021 | 0.000 | -0.2705 | No |
| 6 | GRM5 | glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597] | 10025 | 0.000 | -0.2706 | No |
| 7 | GRIN2C | glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587] | 10407 | 0.000 | -0.2809 | No |
| 8 | GRIN3A | glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767] | 10411 | 0.000 | -0.2810 | No |
| 9 | GLRA1 | glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326] | 12990 | 0.000 | -0.3506 | No |
| 10 | GLRA2 | glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327] | 12993 | 0.000 | -0.3506 | No |
| 11 | CHRFAM7A | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion [Source:HGNC Symbol;Acc:HGNC:15781] | 13259 | 0.000 | -0.3578 | No |
| 12 | GABRE | gamma-aminobutyric acid type A receptor subunit epsilon [Source:HGNC Symbol;Acc:HGNC:4085] | 17334 | 0.000 | -0.4678 | No |
| 13 | CHRND | cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965] | 17854 | 0.000 | -0.4818 | No |
| 14 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17855 | 0.000 | -0.4818 | No |
| 15 | CHRNE | cholinergic receptor nicotinic epsilon subunit [Source:HGNC Symbol;Acc:HGNC:1966] | 17856 | 0.000 | -0.4818 | No |
| 16 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17866 | 0.000 | -0.4821 | No |
| 17 | CHRM1 | cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950] | 17868 | 0.000 | -0.4821 | No |
| 18 | CHRM5 | cholinergic receptor muscarinic 5 [Source:HGNC Symbol;Acc:HGNC:1954] | 17869 | 0.000 | -0.4821 | No |
| 19 | ADRB1 | adrenoceptor beta 1 [Source:HGNC Symbol;Acc:HGNC:285] | 17980 | 0.000 | -0.4851 | No |
| 20 | DRD1 | dopamine receptor D1 [Source:HGNC Symbol;Acc:HGNC:3020] | 18537 | 0.000 | -0.5001 | No |
| 21 | DRD2 | dopamine receptor D2 [Source:HGNC Symbol;Acc:HGNC:3023] | 18538 | 0.000 | -0.5001 | No |
| 22 | DRD3 | dopamine receptor D3 [Source:HGNC Symbol;Acc:HGNC:3024] | 18540 | 0.000 | -0.5001 | No |
| 23 | DRD4 | dopamine receptor D4 [Source:HGNC Symbol;Acc:HGNC:3025] | 18541 | 0.000 | -0.5001 | No |
| 24 | DRD5 | dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026] | 18542 | 0.000 | -0.5001 | No |
| 25 | CHRNA10 | cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800] | 19864 | 0.000 | -0.5358 | No |
| 26 | GABRG3 | gamma-aminobutyric acid type A receptor subunit gamma3 [Source:HGNC Symbol;Acc:HGNC:4088] | 19972 | 0.000 | -0.5387 | No |
| 27 | GABRG1 | gamma-aminobutyric acid type A receptor subunit gamma1 [Source:HGNC Symbol;Acc:HGNC:4086] | 19973 | 0.000 | -0.5387 | No |
| 28 | GABRB2 | gamma-aminobutyric acid type A receptor subunit beta2 [Source:HGNC Symbol;Acc:HGNC:4082] | 20021 | 0.000 | -0.5400 | No |
| 29 | GABRB1 | gamma-aminobutyric acid type A receptor subunit beta1 [Source:HGNC Symbol;Acc:HGNC:4081] | 20022 | 0.000 | -0.5400 | No |
| 30 | GABRA2 | gamma-aminobutyric acid type A receptor subunit alpha2 [Source:HGNC Symbol;Acc:HGNC:4076] | 20063 | 0.000 | -0.5410 | No |
| 31 | GABRA1 | gamma-aminobutyric acid type A receptor subunit alpha1 [Source:HGNC Symbol;Acc:HGNC:4075] | 20064 | 0.000 | -0.5410 | No |
| 32 | GABRA6 | gamma-aminobutyric acid type A receptor subunit alpha6 [Source:HGNC Symbol;Acc:HGNC:4080] | 20065 | 0.000 | -0.5410 | No |
| 33 | GABRA5 | gamma-aminobutyric acid type A receptor subunit alpha5 [Source:HGNC Symbol;Acc:HGNC:4079] | 20066 | 0.000 | -0.5410 | No |
| 34 | GABRA4 | gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078] | 20067 | 0.000 | -0.5410 | No |
| 35 | GABRA3 | gamma-aminobutyric acid type A receptor subunit alpha3 [Source:HGNC Symbol;Acc:HGNC:4077] | 20068 | 0.000 | -0.5410 | No |
| 36 | CHRNB3 | cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963] | 21914 | 0.000 | -0.5909 | No |
| 37 | CHRNA1 | cholinergic receptor nicotinic alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:1955] | 21937 | 0.000 | -0.5915 | No |
| 38 | CHRNA3 | cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957] | 21941 | 0.000 | -0.5915 | No |
| 39 | CHRNA2 | cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956] | 21942 | 0.000 | -0.5915 | No |
| 40 | CHRNA5 | cholinergic receptor nicotinic alpha 5 subunit [Source:HGNC Symbol;Acc:HGNC:1959] | 21943 | 0.000 | -0.5915 | No |
| 41 | CHRNA4 | cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958] | 21945 | 0.000 | -0.5916 | No |
| 42 | CHRNA7 | cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960] | 21946 | 0.000 | -0.5916 | No |
| 43 | CHRNA6 | cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963] | 21949 | 0.000 | -0.5916 | No |
| 44 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 21952 | 0.000 | -0.5917 | No |
| 45 | GRIK3 | glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581] | 22483 | 0.000 | -0.6060 | No |
| 46 | GRIK4 | glutamate ionotropic receptor kainate type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4582] | 22484 | 0.000 | -0.6060 | No |
| 47 | GRIK1 | glutamate ionotropic receptor kainate type subunit 1 [Source:HGNC Symbol;Acc:HGNC:4579] | 22485 | 0.000 | -0.6060 | No |
| 48 | GRIK2 | glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580] | 22486 | 0.000 | -0.6060 | No |
| 49 | HRH3 | histamine receptor H3 [Source:HGNC Symbol;Acc:HGNC:5184] | 24153 | 0.000 | -0.6510 | No |
| 50 | HRH4 | histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383] | 24158 | 0.000 | -0.6511 | No |
| 51 | GABRR2 | gamma-aminobutyric acid type A receptor subunit rho2 [Source:HGNC Symbol;Acc:HGNC:4091] | 24845 | 0.000 | -0.6696 | No |
| 52 | GABRR1 | gamma-aminobutyric acid type A receptor subunit rho1 [Source:HGNC Symbol;Acc:HGNC:4090] | 24847 | 0.000 | -0.6696 | No |
| 53 | GLRB | glycine receptor beta [Source:HGNC Symbol;Acc:HGNC:4329] | 26865 | 0.000 | -0.7241 | No |
| 54 | GABBR1 | gamma-aminobutyric acid type B receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:4070] | 27282 | 0.000 | -0.7353 | No |
| 55 | GABRG2 | gamma-aminobutyric acid type A receptor subunit gamma2 [Source:HGNC Symbol;Acc:HGNC:4087] | 29303 | -0.243 | -0.7667 | Yes |
| 56 | CHRM3 | cholinergic receptor muscarinic 3 [Source:HGNC Symbol;Acc:HGNC:1952] | 30090 | -0.342 | -0.7552 | Yes |
| 57 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 30187 | -0.370 | -0.7225 | Yes |
| 58 | CHRNB2 | cholinergic receptor nicotinic beta 2 subunit [Source:HGNC Symbol;Acc:HGNC:1962] | 32117 | -0.911 | -0.6876 | Yes |
| 59 | ANXA9 | annexin A9 [Source:HGNC Symbol;Acc:HGNC:547] | 33305 | -1.304 | -0.5952 | Yes |
| 60 | GRIK5 | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | 34451 | -1.856 | -0.4488 | Yes |
| 61 | CHRNB4 | cholinergic receptor nicotinic beta 4 subunit [Source:HGNC Symbol;Acc:HGNC:1964] | 34583 | -1.941 | -0.2670 | Yes |
| 62 | CHRNB1 | cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961] | 36521 | -3.504 | 0.0154 | Yes |
