Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | KRAS.KIDNEY_UP.V1_DN |
| Enrichment Score (ES) | 0.4942411 |
| Normalized Enrichment Score (NES) | 1.2666059 |
| Nominal p-value | 0.022727273 |
| FDR q-value | 0.17573002 |
| FWER p-Value | 0.599 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 40 | 4.848 | 0.0486 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 67 | 4.644 | 0.0955 | Yes |
| 3 | PTGER2 | prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594] | 76 | 4.602 | 0.1424 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 110 | 4.400 | 0.1866 | Yes |
| 5 | KCND1 | potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237] | 175 | 4.037 | 0.2262 | Yes |
| 6 | PDCD1 | programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] | 216 | 3.861 | 0.2647 | Yes |
| 7 | NES | nestin [Source:HGNC Symbol;Acc:HGNC:7756] | 318 | 3.407 | 0.2969 | Yes |
| 8 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 351 | 3.322 | 0.3300 | Yes |
| 9 | ETS1 | ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488] | 365 | 3.290 | 0.3634 | Yes |
| 10 | ACTC1 | actin alpha cardiac muscle 1 [Source:HGNC Symbol;Acc:HGNC:143] | 580 | 2.819 | 0.3865 | Yes |
| 11 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.4102 | Yes |
| 12 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 798 | 2.474 | 0.4330 | Yes |
| 13 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 853 | 2.362 | 0.4557 | Yes |
| 14 | EFHD1 | EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] | 870 | 2.332 | 0.4792 | Yes |
| 15 | SRC | SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283] | 1100 | 2.076 | 0.4942 | Yes |
| 16 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 2157 | 1.369 | 0.4797 | No |
| 17 | IL23A | interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488] | 2726 | 1.059 | 0.4752 | No |
| 18 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2910 | 0.974 | 0.4802 | No |
| 19 | CARD9 | caspase recruitment domain family member 9 [Source:HGNC Symbol;Acc:HGNC:16391] | 4692 | 0.416 | 0.4363 | No |
| 20 | LIPE | lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621] | 4938 | 0.358 | 0.4333 | No |
| 21 | SEC31B | SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197] | 5081 | 0.314 | 0.4327 | No |
| 22 | KCNN1 | potassium calcium-activated channel subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:6290] | 5838 | 0.135 | 0.4136 | No |
| 23 | HINFP | histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850] | 5885 | 0.126 | 0.4137 | No |
| 24 | DDX51 | DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082] | 6075 | 0.076 | 0.4093 | No |
| 25 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6444 | 0.000 | 0.3994 | No |
| 26 | CCL27 | C-C motif chemokine ligand 27 [Source:HGNC Symbol;Acc:HGNC:10626] | 6462 | 0.000 | 0.3989 | No |
| 27 | IL1RL2 | interleukin 1 receptor like 2 [Source:HGNC Symbol;Acc:HGNC:5999] | 6980 | 0.000 | 0.3849 | No |
| 28 | EPHA5 | EPH receptor A5 [Source:HGNC Symbol;Acc:HGNC:3389] | 7511 | 0.000 | 0.3706 | No |
| 29 | ASPN | asporin [Source:HGNC Symbol;Acc:HGNC:14872] | 7853 | 0.000 | 0.3613 | No |
| 30 | SGK2 | serum/glucocorticoid regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:13900] | 7959 | 0.000 | 0.3585 | No |
| 31 | OR7A10 | olfactory receptor family 7 subfamily A member 10 [Source:HGNC Symbol;Acc:HGNC:8356] | 8181 | 0.000 | 0.3525 | No |
| 32 | PROP1 | PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455] | 8433 | 0.000 | 0.3457 | No |
| 33 | SIM1 | SIM bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10882] | 8483 | 0.000 | 0.3444 | No |
| 34 | FOLR2 | folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793] | 9547 | 0.000 | 0.3156 | No |
| 35 | SERHL2 | serine hydrolase like 2 [Source:HGNC Symbol;Acc:HGNC:29446] | 9630 | 0.000 | 0.3134 | No |
| 36 | KCNF1 | potassium voltage-gated channel modifier subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:6246] | 9850 | 0.000 | 0.3075 | No |
| 37 | CETP | cholesteryl ester transfer protein [Source:HGNC Symbol;Acc:HGNC:1869] | 9923 | 0.000 | 0.3055 | No |
| 38 | GRM2 | glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594] | 10023 | 0.000 | 0.3029 | No |
| 39 | GRM4 | glutamate metabotropic receptor 4 [Source:HGNC Symbol;Acc:HGNC:4596] | 10026 | 0.000 | 0.3028 | No |
| 40 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 10029 | 0.000 | 0.3028 | No |
| 41 | AADAC | arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] | 10441 | 0.000 | 0.2916 | No |
| 42 | LRRC31 | leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] | 11483 | 0.000 | 0.2635 | No |
| 43 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11591 | 0.000 | 0.2606 | No |
| 44 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11599 | 0.000 | 0.2604 | No |
| 45 | PRG2 | proteoglycan 2, pro eosinophil major basic protein [Source:HGNC Symbol;Acc:HGNC:9362] | 11620 | 0.000 | 0.2598 | No |
| 46 | LMAN1L | lectin, mannose binding 1 like [Source:HGNC Symbol;Acc:HGNC:6632] | 11943 | 0.000 | 0.2511 | No |
| 47 | SLC6A20 | solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927] | 11968 | 0.000 | 0.2505 | No |
| 48 | RYR2 | ryanodine receptor 2 [Source:HGNC Symbol;Acc:HGNC:10484] | 11994 | 0.000 | 0.2498 | No |
| 49 | AGRP | agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330] | 12227 | 0.000 | 0.2435 | No |
| 50 | CNN1 | calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155] | 12402 | 0.000 | 0.2388 | No |
| 51 | ADAMTSL2 | ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631] | 12674 | 0.000 | 0.2315 | No |
| 52 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 12737 | 0.000 | 0.2298 | No |
| 53 | TENM2 | teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] | 12801 | 0.000 | 0.2281 | No |
| 54 | THRB | thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799] | 12860 | 0.000 | 0.2265 | No |
| 55 | TACR2 | tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527] | 13264 | 0.000 | 0.2156 | No |
| 56 | ZDHHC8P1 | ZDHHC8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:26461] | 13294 | 0.000 | 0.2148 | No |
| 57 | LILRA4 | leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503] | 13498 | 0.000 | 0.2094 | No |
| 58 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13505 | 0.000 | 0.2092 | No |
| 59 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 13597 | 0.000 | 0.2067 | No |
| 60 | IL26 | interleukin 26 [Source:HGNC Symbol;Acc:HGNC:17119] | 13842 | 0.000 | 0.2001 | No |
| 61 | TMEM262 | transmembrane protein 262 [Source:HGNC Symbol;Acc:HGNC:49389] | 13923 | 0.000 | 0.1980 | No |
| 62 | KRT2 | keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439] | 14258 | 0.000 | 0.1889 | No |
| 63 | B3GALT5 | beta-1,3-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:920] | 14589 | 0.000 | 0.1800 | No |
| 64 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898] | 15997 | 0.000 | 0.1419 | No |
| 65 | C3orf36 | chromosome 3 putative open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:26170] | 16025 | 0.000 | 0.1412 | No |
| 66 | TTLL2 | tubulin tyrosine ligase like 2 [Source:HGNC Symbol;Acc:HGNC:21211] | 16190 | 0.000 | 0.1368 | No |
| 67 | HYAL4 | hyaluronidase 4 [Source:HGNC Symbol;Acc:HGNC:5323] | 16282 | 0.000 | 0.1343 | No |
| 68 | HRG | histidine rich glycoprotein [Source:HGNC Symbol;Acc:HGNC:5181] | 17509 | 0.000 | 0.1011 | No |
| 69 | SLC9A3 | solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] | 17583 | 0.000 | 0.0991 | No |
| 70 | CHRNG | cholinergic receptor nicotinic gamma subunit [Source:HGNC Symbol;Acc:HGNC:1967] | 17855 | 0.000 | 0.0918 | No |
| 71 | CHRM2 | cholinergic receptor muscarinic 2 [Source:HGNC Symbol;Acc:HGNC:1951] | 17866 | 0.000 | 0.0915 | No |
| 72 | IFNA17 | interferon alpha 17 [Source:HGNC Symbol;Acc:HGNC:5422] | 18233 | 0.000 | 0.0816 | No |
| 73 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 18239 | 0.000 | 0.0815 | No |
| 74 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18985 | 0.000 | 0.0613 | No |
| 75 | DSG3 | desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050] | 19002 | 0.000 | 0.0609 | No |
| 76 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19125 | 0.000 | 0.0576 | No |
| 77 | BMP4 | bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071] | 19147 | 0.000 | 0.0570 | No |
| 78 | EPS8L3 | EPS8 like 3 [Source:HGNC Symbol;Acc:HGNC:21297] | 19212 | 0.000 | 0.0553 | No |
| 79 | NGF | nerve growth factor [Source:HGNC Symbol;Acc:HGNC:7808] | 19357 | 0.000 | 0.0514 | No |
| 80 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19862 | 0.000 | 0.0378 | No |
| 81 | VILL | villin like [Source:HGNC Symbol;Acc:HGNC:30906] | 19905 | 0.000 | 0.0366 | No |
| 82 | NR1I3 | nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969] | 20044 | 0.000 | 0.0329 | No |
| 83 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 [Source:HGNC Symbol;Acc:HGNC:808] | 20425 | 0.000 | 0.0226 | No |
| 84 | FOXA1 | forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021] | 20780 | 0.000 | 0.0130 | No |
| 85 | NPPB | natriuretic peptide B [Source:HGNC Symbol;Acc:HGNC:7940] | 20784 | 0.000 | 0.0130 | No |
| 86 | TCP10L3 | t-complex 10 like 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:11656] | 20949 | 0.000 | 0.0085 | No |
| 87 | IGKV3D-15 | immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824] | 20967 | 0.000 | 0.0081 | No |
| 88 | NPFFR1 | neuropeptide FF receptor 1 [Source:HGNC Symbol;Acc:HGNC:17425] | 21367 | 0.000 | -0.0027 | No |
| 89 | CST5 | cystatin D [Source:HGNC Symbol;Acc:HGNC:2477] | 21882 | 0.000 | -0.0166 | No |
| 90 | CHRNA9 | cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079] | 21952 | 0.000 | -0.0185 | No |
| 91 | PRSS21 | serine protease 21 [Source:HGNC Symbol;Acc:HGNC:9485] | 22431 | 0.000 | -0.0314 | No |
| 92 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 23050 | 0.000 | -0.0482 | No |
| 93 | CAPN9 | calpain 9 [Source:HGNC Symbol;Acc:HGNC:1486] | 23250 | 0.000 | -0.0536 | No |
| 94 | ABCB11 | ATP binding cassette subfamily B member 11 [Source:HGNC Symbol;Acc:HGNC:42] | 23725 | 0.000 | -0.0664 | No |
| 95 | PAGE1 | PAGE family member 1 [Source:HGNC Symbol;Acc:HGNC:4107] | 23880 | 0.000 | -0.0705 | No |
| 96 | MAGEA10 | MAGE family member A10 [Source:HGNC Symbol;Acc:HGNC:6797] | 23887 | 0.000 | -0.0707 | No |
| 97 | ITIH5 | inter-alpha-trypsin inhibitor heavy chain 5 [Source:HGNC Symbol;Acc:HGNC:21449] | 24305 | 0.000 | -0.0820 | No |
| 98 | FCHO1 | FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002] | 24319 | 0.000 | -0.0823 | No |
| 99 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 24502 | 0.000 | -0.0873 | No |
| 100 | BAAT | bile acid-CoA:amino acid N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:932] | 24524 | 0.000 | -0.0878 | No |
| 101 | KLHDC8A | kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] | 24835 | 0.000 | -0.0962 | No |
| 102 | TCF21 | transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11632] | 25225 | 0.000 | -0.1068 | No |
| 103 | KLK1 | kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] | 25418 | 0.000 | -0.1119 | No |
| 104 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 26058 | 0.000 | -0.1292 | No |
| 105 | INSL5 | insulin like 5 [Source:HGNC Symbol;Acc:HGNC:6088] | 26828 | 0.000 | -0.1500 | No |
| 106 | INSL4 | insulin like 4 [Source:HGNC Symbol;Acc:HGNC:6087] | 26829 | 0.000 | -0.1500 | No |
| 107 | KRT17 | keratin 17 [Source:HGNC Symbol;Acc:HGNC:6427] | 26970 | 0.000 | -0.1538 | No |
| 108 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875] | 27918 | 0.000 | -0.1795 | No |
| 109 | CLEC3B | C-type lectin domain family 3 member B [Source:HGNC Symbol;Acc:HGNC:11891] | 28354 | -0.000 | -0.1912 | No |
| 110 | RBIS | ribosomal biogenesis factor [Source:HGNC Symbol;Acc:HGNC:32235] | 28522 | -0.043 | -0.1953 | No |
| 111 | CBL | Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541] | 28819 | -0.128 | -0.2020 | No |
| 112 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 29266 | -0.234 | -0.2117 | No |
| 113 | HHIPL2 | HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842] | 29521 | -0.304 | -0.2154 | No |
| 114 | APBB3 | amyloid beta precursor protein binding family B member 3 [Source:HGNC Symbol;Acc:HGNC:20708] | 30496 | -0.445 | -0.2372 | No |
| 115 | TYROBP | transmembrane immune signaling adaptor TYROBP [Source:HGNC Symbol;Acc:HGNC:12449] | 30769 | -0.519 | -0.2393 | No |
| 116 | CACNA1S | calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397] | 32001 | -0.874 | -0.2636 | No |
| 117 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 32093 | -0.905 | -0.2568 | No |
| 118 | RPL10P17 | ribosomal protein L10 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52348] | 32200 | -0.938 | -0.2501 | No |
| 119 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit [Source:HGNC Symbol;Acc:HGNC:18423] | 33018 | -1.211 | -0.2598 | No |
| 120 | MDFI | MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967] | 33194 | -1.286 | -0.2513 | No |
| 121 | KIF21B | kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] | 33220 | -1.295 | -0.2387 | No |
| 122 | KLF3 | Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516] | 34431 | -1.843 | -0.2526 | No |
| 123 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560] | 34558 | -1.928 | -0.2363 | No |
| 124 | GPR35 | G protein-coupled receptor 35 [Source:HGNC Symbol;Acc:HGNC:4492] | 34604 | -1.945 | -0.2175 | No |
| 125 | ECEL1 | endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147] | 34621 | -1.945 | -0.1980 | No |
| 126 | EGFL7 | EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594] | 34686 | -1.945 | -0.1798 | No |
| 127 | ABCA3 | ATP binding cassette subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:33] | 35049 | -2.135 | -0.1678 | No |
| 128 | SEMA5A | semaphorin 5A [Source:HGNC Symbol;Acc:HGNC:10736] | 35147 | -2.201 | -0.1478 | No |
| 129 | DRC3 | dynein regulatory complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:25384] | 35165 | -2.217 | -0.1256 | No |
| 130 | CBARP | CACN subunit beta associated regulatory protein [Source:HGNC Symbol;Acc:HGNC:28617] | 35400 | -2.378 | -0.1075 | No |
| 131 | TREM2 | triggering receptor expressed on myeloid cells 2 [Source:HGNC Symbol;Acc:HGNC:17761] | 35487 | -2.434 | -0.0849 | No |
| 132 | PHLDA3 | pleckstrin homology like domain family A member 3 [Source:HGNC Symbol;Acc:HGNC:8934] | 35731 | -2.634 | -0.0645 | No |
| 133 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 35954 | -2.799 | -0.0419 | No |
| 134 | BRDT | bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105] | 36307 | -3.198 | -0.0186 | No |
| 135 | H2AC13 | H2A clustered histone 13 [Source:HGNC Symbol;Acc:HGNC:4725] | 36737 | -3.884 | 0.0096 | No |
