Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | RB_DN.V1_DN |
| Enrichment Score (ES) | 0.5363874 |
| Normalized Enrichment Score (NES) | 1.3820238 |
| Nominal p-value | 0.013071896 |
| FDR q-value | 0.124721125 |
| FWER p-Value | 0.279 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CISH | cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] | 27 | 4.906 | 0.0364 | Yes |
| 2 | TNC | tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] | 34 | 4.879 | 0.0732 | Yes |
| 3 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 66 | 4.648 | 0.1076 | Yes |
| 4 | MYORG | myogenesis regulating glycosidase (putative) [Source:HGNC Symbol;Acc:HGNC:19918] | 92 | 4.522 | 0.1412 | Yes |
| 5 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 104 | 4.459 | 0.1747 | Yes |
| 6 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 129 | 4.309 | 0.2067 | Yes |
| 7 | FURIN | furin, paired basic amino acid cleaving enzyme [Source:HGNC Symbol;Acc:HGNC:8568] | 136 | 4.283 | 0.2390 | Yes |
| 8 | LGALS9 | galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570] | 172 | 4.056 | 0.2687 | Yes |
| 9 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 296 | 3.500 | 0.2919 | Yes |
| 10 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 550 | 2.906 | 0.3071 | Yes |
| 11 | MMP13 | matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159] | 623 | 2.784 | 0.3262 | Yes |
| 12 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 643 | 2.751 | 0.3466 | Yes |
| 13 | ATF5 | activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790] | 982 | 2.231 | 0.3543 | Yes |
| 14 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 985 | 2.230 | 0.3712 | Yes |
| 15 | SLC7A5 | solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] | 1039 | 2.146 | 0.3860 | Yes |
| 16 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 1043 | 2.144 | 0.4021 | Yes |
| 17 | PSMB10 | proteasome 20S subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538] | 1131 | 2.023 | 0.4151 | Yes |
| 18 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] | 1137 | 2.017 | 0.4303 | Yes |
| 19 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 1227 | 1.926 | 0.4424 | Yes |
| 20 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 1243 | 1.908 | 0.4565 | Yes |
| 21 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 1257 | 1.895 | 0.4705 | Yes |
| 22 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1491 | 1.692 | 0.4770 | Yes |
| 23 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 1750 | 1.508 | 0.4815 | Yes |
| 24 | STC2 | stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] | 1878 | 1.438 | 0.4889 | Yes |
| 25 | MVP | major vault protein [Source:HGNC Symbol;Acc:HGNC:7531] | 2390 | 1.222 | 0.4843 | Yes |
| 26 | ANKFY1 | ankyrin repeat and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20763] | 2551 | 1.138 | 0.4886 | Yes |
| 27 | DDX3Y | DEAD-box helicase 3 Y-linked [Source:HGNC Symbol;Acc:HGNC:2699] | 2630 | 1.101 | 0.4949 | Yes |
| 28 | PPP2R1B | protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303] | 2641 | 1.094 | 0.5029 | Yes |
| 29 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 2950 | 0.951 | 0.5018 | Yes |
| 30 | DYNLL1 | dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476] | 3039 | 0.927 | 0.5064 | Yes |
| 31 | P4HA1 | prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546] | 3103 | 0.903 | 0.5115 | Yes |
| 32 | DDIT3 | DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] | 3382 | 0.809 | 0.5101 | Yes |
| 33 | UROS | uroporphyrinogen III synthase [Source:HGNC Symbol;Acc:HGNC:12592] | 3409 | 0.798 | 0.5155 | Yes |
| 34 | PRKAR1A | protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388] | 3428 | 0.793 | 0.5210 | Yes |
| 35 | STARD3NL | STARD3 N-terminal like [Source:HGNC Symbol;Acc:HGNC:19169] | 3645 | 0.710 | 0.5205 | Yes |
| 36 | ARL1 | ADP ribosylation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:692] | 3671 | 0.697 | 0.5251 | Yes |
| 37 | BCCIP | BRCA2 and CDKN1A interacting protein [Source:HGNC Symbol;Acc:HGNC:978] | 3698 | 0.689 | 0.5297 | Yes |
| 38 | DNAJC4 | DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271] | 4028 | 0.597 | 0.5253 | Yes |
| 39 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 4165 | 0.557 | 0.5258 | Yes |
| 40 | CREB3L2 | cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720] | 4179 | 0.552 | 0.5297 | Yes |
| 41 | MSMO1 | methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] | 4211 | 0.542 | 0.5329 | Yes |
| 42 | SH3BP5L | SH3 binding domain protein 5 like [Source:HGNC Symbol;Acc:HGNC:29360] | 4234 | 0.535 | 0.5364 | Yes |
| 43 | CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase [Source:HGNC Symbol;Acc:HGNC:1769] | 4526 | 0.462 | 0.5320 | No |
| 44 | NFIL3 | nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787] | 4596 | 0.442 | 0.5335 | No |
| 45 | LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606] | 4629 | 0.433 | 0.5359 | No |
| 46 | UBA5 | ubiquitin like modifier activating enzyme 5 [Source:HGNC Symbol;Acc:HGNC:23230] | 4819 | 0.389 | 0.5337 | No |
| 47 | DDIT4 | DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944] | 5060 | 0.321 | 0.5297 | No |
| 48 | RPS2 | ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404] | 5446 | 0.232 | 0.5210 | No |
| 49 | LAMB3 | laminin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6490] | 5657 | 0.175 | 0.5167 | No |
| 50 | EFL1 | elongation factor like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25789] | 5694 | 0.168 | 0.5170 | No |
| 51 | FEZ2 | fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660] | 5803 | 0.140 | 0.5151 | No |
| 52 | PDCD6 | programmed cell death 6 [Source:HGNC Symbol;Acc:HGNC:8765] | 5804 | 0.140 | 0.5162 | No |
| 53 | PMVK | phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] | 5905 | 0.122 | 0.5144 | No |
| 54 | TUBA4A | tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407] | 5989 | 0.101 | 0.5129 | No |
| 55 | BASP1 | brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957] | 6087 | 0.071 | 0.5108 | No |
| 56 | SMIM3 | small integral membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:30248] | 6548 | 0.000 | 0.4984 | No |
| 57 | CALCB | calcitonin related polypeptide beta [Source:HGNC Symbol;Acc:HGNC:1438] | 8862 | 0.000 | 0.4358 | No |
| 58 | LCE5A | late cornified envelope 5A [Source:HGNC Symbol;Acc:HGNC:16614] | 9431 | 0.000 | 0.4205 | No |
| 59 | RASL11B | RAS like family 11 member B [Source:HGNC Symbol;Acc:HGNC:23804] | 9791 | 0.000 | 0.4107 | No |
| 60 | ADAM12 | ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190] | 9989 | 0.000 | 0.4054 | No |
| 61 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10064 | 0.000 | 0.4034 | No |
| 62 | PPBP | pro-platelet basic protein [Source:HGNC Symbol;Acc:HGNC:9240] | 11051 | 0.000 | 0.3767 | No |
| 63 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 11174 | 0.000 | 0.3734 | No |
| 64 | C10orf99 | chromosome 10 open reading frame 99 [Source:HGNC Symbol;Acc:HGNC:31428] | 11218 | 0.000 | 0.3723 | No |
| 65 | S100A16 | S100 calcium binding protein A16 [Source:HGNC Symbol;Acc:HGNC:20441] | 11801 | 0.000 | 0.3565 | No |
| 66 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11881 | 0.000 | 0.3544 | No |
| 67 | AGR3 | anterior gradient 3, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:24167] | 12212 | 0.000 | 0.3455 | No |
| 68 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12511 | 0.000 | 0.3374 | No |
| 69 | MOXD1 | monooxygenase DBH like 1 [Source:HGNC Symbol;Acc:HGNC:21063] | 13070 | 0.000 | 0.3223 | No |
| 70 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 13515 | 0.000 | 0.3103 | No |
| 71 | IL33 | interleukin 33 [Source:HGNC Symbol;Acc:HGNC:16028] | 13899 | 0.000 | 0.2999 | No |
| 72 | TLL1 | tolloid like 1 [Source:HGNC Symbol;Acc:HGNC:11843] | 14226 | 0.000 | 0.2911 | No |
| 73 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893] | 16368 | 0.000 | 0.2332 | No |
| 74 | H19 | H19 imprinted maternally expressed transcript [Source:HGNC Symbol;Acc:HGNC:4713] | 17149 | 0.000 | 0.2121 | No |
| 75 | S1PR5 | sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299] | 18030 | 0.000 | 0.1883 | No |
| 76 | BNC1 | basonuclin 1 [Source:HGNC Symbol;Acc:HGNC:1081] | 19347 | 0.000 | 0.1527 | No |
| 77 | LAMC2 | laminin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:6493] | 20820 | 0.000 | 0.1129 | No |
| 78 | C18orf32 | chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690] | 21663 | 0.000 | 0.0901 | No |
| 79 | CST9 | cystatin 9 [Source:HGNC Symbol;Acc:HGNC:13261] | 21878 | 0.000 | 0.0843 | No |
| 80 | WNT3 | Wnt family member 3 [Source:HGNC Symbol;Acc:HGNC:12782] | 22301 | 0.000 | 0.0729 | No |
| 81 | FHL1 | four and a half LIM domains 1 [Source:HGNC Symbol;Acc:HGNC:3702] | 23162 | 0.000 | 0.0496 | No |
| 82 | SLCO2A1 | solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955] | 23973 | 0.000 | 0.0277 | No |
| 83 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10870] | 24381 | 0.000 | 0.0167 | No |
| 84 | H2BC14 | H2B clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4750] | 24471 | 0.000 | 0.0143 | No |
| 85 | GJB2 | gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] | 25852 | 0.000 | -0.0230 | No |
| 86 | F2RL1 | F2R like trypsin receptor 1 [Source:HGNC Symbol;Acc:HGNC:3538] | 26107 | 0.000 | -0.0299 | No |
| 87 | IRX4 | iroquois homeobox 4 [Source:HGNC Symbol;Acc:HGNC:6129] | 26861 | 0.000 | -0.0503 | No |
| 88 | LRRC4 | leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586] | 27805 | 0.000 | -0.0758 | No |
| 89 | TMEM50B | transmembrane protein 50B [Source:HGNC Symbol;Acc:HGNC:1280] | 28470 | -0.027 | -0.0935 | No |
| 90 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850] | 28614 | -0.068 | -0.0969 | No |
| 91 | TMEM42 | transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444] | 28654 | -0.082 | -0.0973 | No |
| 92 | LMAN1 | lectin, mannose binding 1 [Source:HGNC Symbol;Acc:HGNC:6631] | 28685 | -0.088 | -0.0975 | No |
| 93 | SARAF | store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789] | 28827 | -0.131 | -0.1003 | No |
| 94 | EIF4E | eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287] | 29067 | -0.195 | -0.1053 | No |
| 95 | GOSR2 | golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431] | 29309 | -0.245 | -0.1099 | No |
| 96 | NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] | 29417 | -0.275 | -0.1107 | No |
| 97 | CAP1 | cyclase associated actin cytoskeleton regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:20040] | 29422 | -0.277 | -0.1088 | No |
| 98 | TMCC3 | transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199] | 29665 | -0.320 | -0.1129 | No |
| 99 | SLC7A3 | solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061] | 29685 | -0.320 | -0.1110 | No |
| 100 | NKAP | NFKB activating protein [Source:HGNC Symbol;Acc:HGNC:29873] | 30089 | -0.342 | -0.1193 | No |
| 101 | SQLE | squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] | 31052 | -0.603 | -0.1407 | No |
| 102 | MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] | 31255 | -0.654 | -0.1412 | No |
| 103 | TRAPPC12 | trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284] | 31573 | -0.755 | -0.1441 | No |
| 104 | CYTH1 | cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501] | 31577 | -0.757 | -0.1384 | No |
| 105 | ANKRD40 | ankyrin repeat domain 40 [Source:HGNC Symbol;Acc:HGNC:28233] | 32052 | -0.891 | -0.1445 | No |
| 106 | CDC42SE2 | CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547] | 32367 | -0.989 | -0.1455 | No |
| 107 | NSDHL | NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] | 32387 | -0.997 | -0.1385 | No |
| 108 | DUSP14 | dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] | 32525 | -1.025 | -0.1344 | No |
| 109 | FAM102A | family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419] | 32621 | -1.061 | -0.1289 | No |
| 110 | ANXA11 | annexin A11 [Source:HGNC Symbol;Acc:HGNC:535] | 32860 | -1.151 | -0.1267 | No |
| 111 | UNC119B | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] | 32882 | -1.159 | -0.1185 | No |
| 112 | SEC23A | Sec23 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10701] | 32976 | -1.194 | -0.1119 | No |
| 113 | H2BC4 | H2B clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4757] | 33312 | -1.304 | -0.1111 | No |
| 114 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 33604 | -1.436 | -0.1081 | No |
| 115 | CAV1 | caveolin 1 [Source:HGNC Symbol;Acc:HGNC:1527] | 33805 | -1.524 | -0.1020 | No |
| 116 | ANXA6 | annexin A6 [Source:HGNC Symbol;Acc:HGNC:544] | 34292 | -1.763 | -0.1018 | No |
| 117 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 34595 | -1.945 | -0.0952 | No |
| 118 | LIFR | LIF receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6597] | 35794 | -2.694 | -0.1072 | No |
| 119 | NDRG1 | N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679] | 36490 | -3.476 | -0.0997 | No |
| 120 | CTNNAL1 | catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] | 36540 | -3.530 | -0.0742 | No |
| 121 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36681 | -3.791 | -0.0493 | No |
| 122 | PLXNA2 | plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100] | 36759 | -3.923 | -0.0217 | No |
| 123 | COL18A1 | collagen type XVIII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2195] | 36817 | -4.038 | 0.0074 | No |
