Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_DN.V1_UP |
| Enrichment Score (ES) | -0.633494 |
| Normalized Enrichment Score (NES) | -1.3812579 |
| Nominal p-value | 0.0072202166 |
| FDR q-value | 0.12901817 |
| FWER p-Value | 0.688 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ID1 | inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360] | 60 | 4.703 | 0.0273 | No |
| 2 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 81 | 4.587 | 0.0550 | No |
| 3 | IER2 | immediate early response 2 [Source:HGNC Symbol;Acc:HGNC:28871] | 698 | 2.643 | 0.0547 | No |
| 4 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1014 | 2.184 | 0.0596 | No |
| 5 | SLC7A7 | solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065] | 1077 | 2.098 | 0.0708 | No |
| 6 | FBP1 | fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] | 1204 | 1.951 | 0.0794 | No |
| 7 | BTG2 | BTG anti-proliferation factor 2 [Source:HGNC Symbol;Acc:HGNC:1131] | 1205 | 1.949 | 0.0914 | No |
| 8 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864] | 1325 | 1.849 | 0.0996 | No |
| 9 | PLA2G6 | phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039] | 1418 | 1.741 | 0.1078 | No |
| 10 | PRKAB1 | protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378] | 1866 | 1.443 | 0.1046 | No |
| 11 | ZSCAN22 | zinc finger and SCAN domain containing 22 [Source:HGNC Symbol;Acc:HGNC:4929] | 2237 | 1.320 | 0.1028 | No |
| 12 | ADGRE1 | adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336] | 2514 | 1.162 | 0.1025 | No |
| 13 | CRIP2 | cysteine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2361] | 3708 | 0.689 | 0.0744 | No |
| 14 | GAB3 | GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515] | 3769 | 0.689 | 0.0770 | No |
| 15 | MDM2 | MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973] | 3906 | 0.640 | 0.0773 | No |
| 16 | PRKCE | protein kinase C epsilon [Source:HGNC Symbol;Acc:HGNC:9401] | 3911 | 0.638 | 0.0811 | No |
| 17 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 4529 | 0.462 | 0.0673 | No |
| 18 | MRPL49 | mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:HGNC:1176] | 4897 | 0.368 | 0.0596 | No |
| 19 | NUDT5 | nudix hydrolase 5 [Source:HGNC Symbol;Acc:HGNC:8052] | 5186 | 0.289 | 0.0536 | No |
| 20 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 5243 | 0.278 | 0.0538 | No |
| 21 | TGM1 | transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777] | 5360 | 0.249 | 0.0522 | No |
| 22 | POLD4 | DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106] | 5463 | 0.226 | 0.0508 | No |
| 23 | UCK1 | uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859] | 6034 | 0.090 | 0.0360 | No |
| 24 | FXYD6 | FXYD domain containing ion transport regulator 6 [Source:HGNC Symbol;Acc:HGNC:4030] | 6702 | 0.000 | 0.0179 | No |
| 25 | HES1 | hes family bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:5192] | 7264 | 0.000 | 0.0028 | No |
| 26 | HEY2 | hes related family bHLH transcription factor with YRPW motif 2 [Source:HGNC Symbol;Acc:HGNC:4881] | 7368 | 0.000 | -0.0000 | No |
| 27 | ARTN | artemin [Source:HGNC Symbol;Acc:HGNC:727] | 7554 | 0.000 | -0.0050 | No |
| 28 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8967 | 0.000 | -0.0432 | No |
| 29 | TNFRSF18 | TNF receptor superfamily member 18 [Source:HGNC Symbol;Acc:HGNC:11914] | 9370 | 0.000 | -0.0541 | No |
| 30 | GRB7 | growth factor receptor bound protein 7 [Source:HGNC Symbol;Acc:HGNC:4567] | 9924 | 0.000 | -0.0690 | No |
| 31 | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin [Source:HGNC Symbol;Acc:HGNC:9016] | 9926 | 0.000 | -0.0691 | No |
| 32 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 10029 | 0.000 | -0.0718 | No |
| 33 | OVOL2 | ovo like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:15804] | 10799 | 0.000 | -0.0926 | No |
| 34 | LYNX1 | Ly6/neurotoxin 1 [Source:HGNC Symbol;Acc:HGNC:29604] | 11630 | 0.000 | -0.1151 | No |
| 35 | IL36RN | interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561] | 12579 | 0.000 | -0.1407 | No |
| 36 | DDIT4L | DNA damage inducible transcript 4 like [Source:HGNC Symbol;Acc:HGNC:30555] | 13477 | 0.000 | -0.1650 | No |
| 37 | MANSC1 | MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505] | 13968 | 0.000 | -0.1782 | No |
| 38 | PCDH10 | protocadherin 10 [Source:HGNC Symbol;Acc:HGNC:13404] | 14709 | 0.000 | -0.1982 | No |
| 39 | NOXO1 | NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] | 15511 | 0.000 | -0.2199 | No |
| 40 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16031 | 0.000 | -0.2339 | No |
| 41 | PALMD | palmdelphin [Source:HGNC Symbol;Acc:HGNC:15846] | 16714 | 0.000 | -0.2524 | No |
| 42 | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 [Source:HGNC Symbol;Acc:HGNC:11251] | 17081 | 0.000 | -0.2623 | No |
| 43 | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [Source:HGNC Symbol;Acc:HGNC:11097] | 19836 | 0.000 | -0.3368 | No |
| 44 | SFRP1 | secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] | 20713 | 0.000 | -0.3605 | No |
| 45 | SNAP25 | synaptosome associated protein 25 [Source:HGNC Symbol;Acc:HGNC:11132] | 21292 | 0.000 | -0.3761 | No |
| 46 | DUOXA1 | dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] | 23253 | 0.000 | -0.4291 | No |
| 47 | TMEM54 | transmembrane protein 54 [Source:HGNC Symbol;Acc:HGNC:24143] | 24981 | 0.000 | -0.4758 | No |
| 48 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 26849 | 0.000 | -0.5263 | No |
| 49 | GNB1L | G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397] | 28468 | -0.026 | -0.5699 | No |
| 50 | ALPK3 | alpha kinase 3 [Source:HGNC Symbol;Acc:HGNC:17574] | 28622 | -0.071 | -0.5736 | No |
| 51 | SLC2A9 | solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446] | 28722 | -0.100 | -0.5757 | No |
| 52 | PLEKHA6 | pleckstrin homology domain containing A6 [Source:HGNC Symbol;Acc:HGNC:17053] | 28914 | -0.152 | -0.5799 | No |
| 53 | MAN1B1 | mannosidase alpha class 1B member 1 [Source:HGNC Symbol;Acc:HGNC:6823] | 29253 | -0.232 | -0.5876 | No |
| 54 | TKFC | triokinase and FMN cyclase [Source:HGNC Symbol;Acc:HGNC:24552] | 29452 | -0.286 | -0.5912 | No |
| 55 | AHCY | adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343] | 29477 | -0.293 | -0.5900 | No |
| 56 | IFT27 | intraflagellar transport 27 [Source:HGNC Symbol;Acc:HGNC:18626] | 30050 | -0.333 | -0.6035 | No |
| 57 | EI24 | EI24 autophagy associated transmembrane protein [Source:HGNC Symbol;Acc:HGNC:13276] | 30405 | -0.421 | -0.6104 | No |
| 58 | NANS | N-acetylneuraminate synthase [Source:HGNC Symbol;Acc:HGNC:19237] | 30431 | -0.428 | -0.6085 | No |
| 59 | SLC24A1 | solute carrier family 24 member 1 [Source:HGNC Symbol;Acc:HGNC:10975] | 30852 | -0.545 | -0.6165 | No |
| 60 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 30948 | -0.574 | -0.6155 | No |
| 61 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31441 | -0.711 | -0.6245 | No |
| 62 | BAZ1B | bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961] | 31682 | -0.784 | -0.6261 | No |
| 63 | ZW10 | zw10 kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13194] | 31728 | -0.801 | -0.6224 | No |
| 64 | CTDSP1 | CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614] | 31776 | -0.811 | -0.6187 | No |
| 65 | PCBP2 | poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648] | 32017 | -0.879 | -0.6198 | No |
| 66 | AAAS | aladin WD repeat nucleoporin [Source:HGNC Symbol;Acc:HGNC:13666] | 32526 | -1.025 | -0.6272 | Yes |
| 67 | TIPIN | TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750] | 32574 | -1.041 | -0.6220 | Yes |
| 68 | HAT1 | histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821] | 32703 | -1.097 | -0.6187 | Yes |
| 69 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 32870 | -1.154 | -0.6161 | Yes |
| 70 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32872 | -1.155 | -0.6090 | Yes |
| 71 | MAPK13 | mitogen-activated protein kinase 13 [Source:HGNC Symbol;Acc:HGNC:6875] | 32893 | -1.162 | -0.6024 | Yes |
| 72 | MRPL45 | mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:HGNC:16651] | 33224 | -1.297 | -0.6034 | Yes |
| 73 | STUB1 | STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] | 33440 | -1.362 | -0.6008 | Yes |
| 74 | ACOX3 | acyl-CoA oxidase 3, pristanoyl [Source:HGNC Symbol;Acc:HGNC:121] | 33692 | -1.469 | -0.5985 | Yes |
| 75 | MMGT1 | membrane magnesium transporter 1 [Source:HGNC Symbol;Acc:HGNC:28100] | 33758 | -1.500 | -0.5911 | Yes |
| 76 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 33784 | -1.513 | -0.5824 | Yes |
| 77 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 33851 | -1.544 | -0.5747 | Yes |
| 78 | PLXNB2 | plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104] | 33917 | -1.571 | -0.5668 | Yes |
| 79 | PEX11B | peroxisomal biogenesis factor 11 beta [Source:HGNC Symbol;Acc:HGNC:8853] | 33930 | -1.582 | -0.5574 | Yes |
| 80 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34281 | -1.756 | -0.5560 | Yes |
| 81 | PPM1M | protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] | 34337 | -1.791 | -0.5465 | Yes |
| 82 | VPS16 | VPS16 core subunit of CORVET and HOPS complexes [Source:HGNC Symbol;Acc:HGNC:14584] | 34442 | -1.852 | -0.5379 | Yes |
| 83 | PDXP | pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259] | 34450 | -1.855 | -0.5266 | Yes |
| 84 | LCMT1 | leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557] | 34499 | -1.886 | -0.5163 | Yes |
| 85 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 34818 | -1.991 | -0.5127 | Yes |
| 86 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 34835 | -2.003 | -0.5008 | Yes |
| 87 | GANC | glucosidase alpha, neutral C [Source:HGNC Symbol;Acc:HGNC:4139] | 34896 | -2.037 | -0.4898 | Yes |
| 88 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35024 | -2.115 | -0.4803 | Yes |
| 89 | PMS2 | PMS1 homolog 2, mismatch repair system component [Source:HGNC Symbol;Acc:HGNC:9122] | 35055 | -2.140 | -0.4679 | Yes |
| 90 | RAD51C | RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820] | 35197 | -2.243 | -0.4579 | Yes |
| 91 | MRE11 | MRE11 homolog, double strand break repair nuclease [Source:HGNC Symbol;Acc:HGNC:7230] | 35220 | -2.260 | -0.4446 | Yes |
| 92 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35241 | -2.264 | -0.4312 | Yes |
| 93 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35394 | -2.370 | -0.4207 | Yes |
| 94 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35399 | -2.377 | -0.4062 | Yes |
| 95 | SLC35B2 | solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872] | 35460 | -2.410 | -0.3929 | Yes |
| 96 | TPRA1 | transmembrane protein adipocyte associated 1 [Source:HGNC Symbol;Acc:HGNC:30413] | 35566 | -2.495 | -0.3804 | Yes |
| 97 | SPICE1 | spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083] | 35579 | -2.515 | -0.3653 | Yes |
| 98 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35642 | -2.564 | -0.3511 | Yes |
| 99 | BBC3 | BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] | 35677 | -2.592 | -0.3361 | Yes |
| 100 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 35689 | -2.604 | -0.3204 | Yes |
| 101 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 35738 | -2.643 | -0.3054 | Yes |
| 102 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 35959 | -2.812 | -0.2940 | Yes |
| 103 | CLN6 | CLN6 transmembrane ER protein [Source:HGNC Symbol;Acc:HGNC:2077] | 36017 | -2.891 | -0.2777 | Yes |
| 104 | ADA | adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] | 36019 | -2.892 | -0.2600 | Yes |
| 105 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36075 | -2.964 | -0.2432 | Yes |
| 106 | SULF2 | sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392] | 36185 | -3.083 | -0.2272 | Yes |
| 107 | ZFP30 | ZFP30 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:29555] | 36249 | -3.156 | -0.2094 | Yes |
| 108 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36312 | -3.201 | -0.1914 | Yes |
| 109 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36407 | -3.364 | -0.1732 | Yes |
| 110 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 36414 | -3.365 | -0.1527 | Yes |
| 111 | NME4 | NME/NM23 nucleoside diphosphate kinase 4 [Source:HGNC Symbol;Acc:HGNC:7852] | 36562 | -3.565 | -0.1347 | Yes |
| 112 | PMM1 | phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114] | 36593 | -3.631 | -0.1131 | Yes |
| 113 | EPHX1 | epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401] | 36669 | -3.753 | -0.0921 | Yes |
| 114 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36717 | -3.856 | -0.0696 | Yes |
| 115 | DNASE1L1 | deoxyribonuclease 1 like 1 [Source:HGNC Symbol;Acc:HGNC:2957] | 36744 | -3.884 | -0.0464 | Yes |
| 116 | SLC2A8 | solute carrier family 2 member 8 [Source:HGNC Symbol;Acc:HGNC:13812] | 36945 | -4.364 | -0.0249 | Yes |
| 117 | NUMBL | NUMB like endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8061] | 37022 | -4.677 | 0.0018 | Yes |
