Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | RB_P107_DN.V1_UP |
| Enrichment Score (ES) | -0.66879314 |
| Normalized Enrichment Score (NES) | -1.4641457 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05787048 |
| FWER p-Value | 0.239 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 188 | 3.979 | 0.0166 | No |
| 2 | FBN1 | fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] | 317 | 3.408 | 0.0316 | No |
| 3 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 426 | 3.158 | 0.0459 | No |
| 4 | ACTG2 | actin gamma 2, smooth muscle [Source:HGNC Symbol;Acc:HGNC:145] | 471 | 3.087 | 0.0615 | No |
| 5 | SPIRE2 | spire type actin nucleation factor 2 [Source:HGNC Symbol;Acc:HGNC:30623] | 579 | 2.822 | 0.0739 | No |
| 6 | TAGLN | transgelin [Source:HGNC Symbol;Acc:HGNC:11553] | 593 | 2.790 | 0.0887 | No |
| 7 | PML | promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113] | 812 | 2.449 | 0.0962 | No |
| 8 | LCK | LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524] | 1024 | 2.169 | 0.1022 | No |
| 9 | H1-10 | H1.10 linker histone [Source:HGNC Symbol;Acc:HGNC:4722] | 1999 | 1.376 | 0.0834 | No |
| 10 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 2338 | 1.252 | 0.0810 | No |
| 11 | TRPV2 | transient receptor potential cation channel subfamily V member 2 [Source:HGNC Symbol;Acc:HGNC:18082] | 3161 | 0.883 | 0.0636 | No |
| 12 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing [Source:HGNC Symbol;Acc:HGNC:7036] | 3694 | 0.690 | 0.0530 | No |
| 13 | SIVA1 | SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712] | 4529 | 0.462 | 0.0329 | No |
| 14 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 4574 | 0.449 | 0.0342 | No |
| 15 | NXT1 | nuclear transport factor 2 like export factor 1 [Source:HGNC Symbol;Acc:HGNC:15913] | 5243 | 0.278 | 0.0176 | No |
| 16 | BLVRB | biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063] | 5332 | 0.256 | 0.0166 | No |
| 17 | ANAPC11 | anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452] | 5981 | 0.102 | -0.0004 | No |
| 18 | CES5A | carboxylesterase 5A [Source:HGNC Symbol;Acc:HGNC:26459] | 6769 | 0.000 | -0.0217 | No |
| 19 | CD248 | CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219] | 8206 | 0.000 | -0.0605 | No |
| 20 | CDH2 | cadherin 2 [Source:HGNC Symbol;Acc:HGNC:1759] | 9498 | 0.000 | -0.0954 | No |
| 21 | GSTM2 | glutathione S-transferase mu 2 [Source:HGNC Symbol;Acc:HGNC:4634] | 9715 | 0.000 | -0.1013 | No |
| 22 | KCNA1 | potassium voltage-gated channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:6218] | 9756 | 0.000 | -0.1024 | No |
| 23 | ABAT | 4-aminobutyrate aminotransferase [Source:HGNC Symbol;Acc:HGNC:23] | 10632 | 0.000 | -0.1260 | No |
| 24 | FBLN2 | fibulin 2 [Source:HGNC Symbol;Acc:HGNC:3601] | 11372 | 0.000 | -0.1460 | No |
| 25 | LYPD1 | LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] | 12163 | 0.000 | -0.1674 | No |
| 26 | BICC1 | BicC family RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19351] | 12468 | 0.000 | -0.1756 | No |
| 27 | SLIT3 | slit guidance ligand 3 [Source:HGNC Symbol;Acc:HGNC:11087] | 12620 | 0.000 | -0.1797 | No |
| 28 | TEK | TEK receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11724] | 12631 | 0.000 | -0.1800 | No |
| 29 | CDKN1C | cyclin dependent kinase inhibitor 1C [Source:HGNC Symbol;Acc:HGNC:1786] | 12663 | 0.000 | -0.1808 | No |
| 30 | COL1A1 | collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197] | 12941 | 0.000 | -0.1883 | No |
| 31 | COL1A2 | collagen type I alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2198] | 12942 | 0.000 | -0.1883 | No |
| 32 | TMEM119 | transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884] | 13547 | 0.000 | -0.2047 | No |
| 33 | TMEM45B | transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194] | 14862 | 0.000 | -0.2402 | No |
| 34 | BGN | biglycan [Source:HGNC Symbol;Acc:HGNC:1044] | 15542 | 0.000 | -0.2586 | No |
| 35 | DCT | dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2709] | 16031 | 0.000 | -0.2718 | No |
| 36 | SI | sucrase-isomaltase [Source:HGNC Symbol;Acc:HGNC:10856] | 16268 | 0.000 | -0.2782 | No |
| 37 | EFS | embryonal Fyn-associated substrate [Source:HGNC Symbol;Acc:HGNC:16898] | 16341 | 0.000 | -0.2801 | No |
| 38 | COL16A1 | collagen type XVI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2193] | 16487 | 0.000 | -0.2840 | No |
| 39 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 16588 | 0.000 | -0.2868 | No |
| 40 | SRPX2 | sushi repeat containing protein X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30668] | 17546 | 0.000 | -0.3126 | No |
| 41 | COL6A2 | collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212] | 18787 | 0.000 | -0.3462 | No |
| 42 | COL6A1 | collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] | 18788 | 0.000 | -0.3462 | No |
| 43 | FKBP10 | FKBP prolyl isomerase 10 [Source:HGNC Symbol;Acc:HGNC:18169] | 19058 | 0.000 | -0.3535 | No |
| 44 | KHDRBS3 | KH RNA binding domain containing, signal transduction associated 3 [Source:HGNC Symbol;Acc:HGNC:18117] | 19739 | 0.000 | -0.3719 | No |
| 45 | LOXL1 | lysyl oxidase like 1 [Source:HGNC Symbol;Acc:HGNC:6665] | 19884 | 0.000 | -0.3758 | No |
| 46 | COX6B2 | cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] | 21462 | 0.000 | -0.4184 | No |
| 47 | TSSC4 | tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386] | 21777 | 0.000 | -0.4269 | No |
| 48 | SNCG | synuclein gamma [Source:HGNC Symbol;Acc:HGNC:11141] | 23018 | 0.000 | -0.4605 | No |
| 49 | COL5A1 | collagen type V alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2209] | 25106 | 0.000 | -0.5169 | No |
| 50 | EDN2 | endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177] | 26058 | 0.000 | -0.5427 | No |
| 51 | FSTL1 | follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972] | 26301 | 0.000 | -0.5492 | No |
| 52 | TYRP1 | tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450] | 26849 | 0.000 | -0.5640 | No |
| 53 | RBPMS2 | RNA binding protein, mRNA processing factor 2 [Source:HGNC Symbol;Acc:HGNC:19098] | 27454 | 0.000 | -0.5804 | No |
| 54 | FBLN5 | fibulin 5 [Source:HGNC Symbol;Acc:HGNC:3602] | 28510 | -0.039 | -0.6087 | No |
| 55 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845] | 28740 | -0.105 | -0.6143 | No |
| 56 | PCOLCE | procollagen C-endopeptidase enhancer [Source:HGNC Symbol;Acc:HGNC:8738] | 29347 | -0.256 | -0.6293 | No |
| 57 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 29920 | -0.320 | -0.6431 | No |
| 58 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 30083 | -0.340 | -0.6456 | No |
| 59 | PTMA | prothymosin alpha [Source:HGNC Symbol;Acc:HGNC:9623] | 30215 | -0.374 | -0.6471 | No |
| 60 | DYNLT1 | dynein light chain Tctex-type 1 [Source:HGNC Symbol;Acc:HGNC:11697] | 30263 | -0.384 | -0.6463 | No |
| 61 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 30860 | -0.547 | -0.6594 | No |
| 62 | TCFL5 | transcription factor like 5 [Source:HGNC Symbol;Acc:HGNC:11646] | 31045 | -0.601 | -0.6611 | No |
| 63 | S100A4 | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494] | 31114 | -0.618 | -0.6596 | No |
| 64 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31441 | -0.711 | -0.6646 | No |
| 65 | PIDD1 | p53-induced death domain protein 1 [Source:HGNC Symbol;Acc:HGNC:16491] | 31598 | -0.764 | -0.6646 | Yes |
| 66 | ORC6 | origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151] | 31699 | -0.791 | -0.6630 | Yes |
| 67 | IPO9 | importin 9 [Source:HGNC Symbol;Acc:HGNC:19425] | 31900 | -0.848 | -0.6638 | Yes |
| 68 | CDH11 | cadherin 11 [Source:HGNC Symbol;Acc:HGNC:1750] | 31938 | -0.862 | -0.6601 | Yes |
| 69 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 32040 | -0.887 | -0.6581 | Yes |
| 70 | SAMD10 | sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129] | 32078 | -0.902 | -0.6542 | Yes |
| 71 | MRGPRF | MAS related GPR family member F [Source:HGNC Symbol;Acc:HGNC:24828] | 32102 | -0.907 | -0.6498 | Yes |
| 72 | NELFE | negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974] | 32134 | -0.918 | -0.6457 | Yes |
| 73 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 32405 | -1.003 | -0.6475 | Yes |
| 74 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 32611 | -1.058 | -0.6473 | Yes |
| 75 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 32870 | -1.154 | -0.6480 | Yes |
| 76 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 32872 | -1.155 | -0.6418 | Yes |
| 77 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 32900 | -1.167 | -0.6362 | Yes |
| 78 | GINS4 | GINS complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:28226] | 33076 | -1.233 | -0.6342 | Yes |
| 79 | CA2 | carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] | 33098 | -1.242 | -0.6280 | Yes |
| 80 | CD81 | CD81 molecule [Source:HGNC Symbol;Acc:HGNC:1701] | 33398 | -1.340 | -0.6288 | Yes |
| 81 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 33702 | -1.472 | -0.6290 | Yes |
| 82 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 33784 | -1.513 | -0.6230 | Yes |
| 83 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 33849 | -1.543 | -0.6163 | Yes |
| 84 | TUBG1 | tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417] | 33851 | -1.544 | -0.6079 | Yes |
| 85 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 33905 | -1.561 | -0.6009 | Yes |
| 86 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 33951 | -1.590 | -0.5935 | Yes |
| 87 | RPA2 | replication protein A2 [Source:HGNC Symbol;Acc:HGNC:10290] | 33986 | -1.613 | -0.5856 | Yes |
| 88 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 34095 | -1.662 | -0.5795 | Yes |
| 89 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 34106 | -1.671 | -0.5707 | Yes |
| 90 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 34281 | -1.756 | -0.5658 | Yes |
| 91 | DCLRE1A | DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660] | 34525 | -1.907 | -0.5620 | Yes |
| 92 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34557 | -1.928 | -0.5524 | Yes |
| 93 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 34747 | -1.948 | -0.5469 | Yes |
| 94 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 34818 | -1.991 | -0.5380 | Yes |
| 95 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 34857 | -2.014 | -0.5280 | Yes |
| 96 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 34979 | -2.090 | -0.5200 | Yes |
| 97 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35024 | -2.115 | -0.5096 | Yes |
| 98 | PRIM2 | DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370] | 35046 | -2.132 | -0.4986 | Yes |
| 99 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35109 | -2.175 | -0.4885 | Yes |
| 100 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 35155 | -2.211 | -0.4777 | Yes |
| 101 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35313 | -2.314 | -0.4693 | Yes |
| 102 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35394 | -2.370 | -0.4586 | Yes |
| 103 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35642 | -2.564 | -0.4513 | Yes |
| 104 | HEXD | hexosaminidase D [Source:HGNC Symbol;Acc:HGNC:26307] | 35650 | -2.572 | -0.4375 | Yes |
| 105 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 35689 | -2.604 | -0.4244 | Yes |
| 106 | RFC2 | replication factor C subunit 2 [Source:HGNC Symbol;Acc:HGNC:9970] | 35707 | -2.615 | -0.4107 | Yes |
| 107 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 35738 | -2.643 | -0.3971 | Yes |
| 108 | FANCA | FA complementation group A [Source:HGNC Symbol;Acc:HGNC:3582] | 35803 | -2.703 | -0.3841 | Yes |
| 109 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 35940 | -2.787 | -0.3726 | Yes |
| 110 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36073 | -2.962 | -0.3601 | Yes |
| 111 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 36075 | -2.964 | -0.3440 | Yes |
| 112 | PAQR4 | progestin and adipoQ receptor family member 4 [Source:HGNC Symbol;Acc:HGNC:26386] | 36167 | -3.059 | -0.3298 | Yes |
| 113 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 36175 | -3.068 | -0.3134 | Yes |
| 114 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36189 | -3.084 | -0.2969 | Yes |
| 115 | ETHE1 | ETHE1 persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287] | 36245 | -3.142 | -0.2813 | Yes |
| 116 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 36312 | -3.201 | -0.2657 | Yes |
| 117 | WDHD1 | WD repeat and HMG-box DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23170] | 36347 | -3.258 | -0.2489 | Yes |
| 118 | E2F1 | E2F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3113] | 36439 | -3.407 | -0.2329 | Yes |
| 119 | POLE | DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177] | 36485 | -3.468 | -0.2152 | Yes |
| 120 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36578 | -3.600 | -0.1981 | Yes |
| 121 | NRM | nurim [Source:HGNC Symbol;Acc:HGNC:8003] | 36634 | -3.710 | -0.1794 | Yes |
| 122 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 36636 | -3.713 | -0.1593 | Yes |
| 123 | RHEBL1 | RHEB like 1 [Source:HGNC Symbol;Acc:HGNC:21166] | 36640 | -3.718 | -0.1391 | Yes |
| 124 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36717 | -3.856 | -0.1202 | Yes |
| 125 | TRPM1 | transient receptor potential cation channel subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:7146] | 36718 | -3.856 | -0.0993 | Yes |
| 126 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36724 | -3.863 | -0.0784 | Yes |
| 127 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36790 | -3.987 | -0.0585 | Yes |
| 128 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 36811 | -4.029 | -0.0371 | Yes |
| 129 | VEGFB | vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681] | 36819 | -4.040 | -0.0153 | Yes |
| 130 | TCF19 | transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629] | 36871 | -4.158 | 0.0059 | Yes |
