Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | TRAVAGLINI_LUNG_MUCOUS_CELL |
| Enrichment Score (ES) | 0.6162425 |
| Normalized Enrichment Score (NES) | 1.5982995 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07933294 |
| FWER p-Value | 0.379 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 11 | 4.973 | 0.0413 | Yes |
| 2 | SAA1 | serum amyloid A1 [Source:HGNC Symbol;Acc:HGNC:10513] | 22 | 4.935 | 0.0823 | Yes |
| 3 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 33 | 4.883 | 0.1228 | Yes |
| 4 | DUSP5 | dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] | 46 | 4.813 | 0.1627 | Yes |
| 5 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 83 | 4.578 | 0.2000 | Yes |
| 6 | CPD | carboxypeptidase D [Source:HGNC Symbol;Acc:HGNC:2301] | 140 | 4.243 | 0.2340 | Yes |
| 7 | CFB | complement factor B [Source:HGNC Symbol;Acc:HGNC:1037] | 196 | 3.925 | 0.2653 | Yes |
| 8 | TGM2 | transglutaminase 2 [Source:HGNC Symbol;Acc:HGNC:11778] | 264 | 3.603 | 0.2936 | Yes |
| 9 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 285 | 3.544 | 0.3227 | Yes |
| 10 | MDK | midkine [Source:HGNC Symbol;Acc:HGNC:6972] | 357 | 3.305 | 0.3484 | Yes |
| 11 | ANPEP | alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500] | 510 | 2.991 | 0.3693 | Yes |
| 12 | ASS1 | argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758] | 516 | 2.977 | 0.3941 | Yes |
| 13 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 635 | 2.763 | 0.4140 | Yes |
| 14 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.4342 | Yes |
| 15 | CP | ceruloplasmin [Source:HGNC Symbol;Acc:HGNC:2295] | 777 | 2.507 | 0.4532 | Yes |
| 16 | LYN | LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735] | 799 | 2.472 | 0.4733 | Yes |
| 17 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 921 | 2.252 | 0.4888 | Yes |
| 18 | CTSC | cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] | 985 | 2.230 | 0.5058 | Yes |
| 19 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 988 | 2.222 | 0.5243 | Yes |
| 20 | IRAK3 | interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020] | 1499 | 1.684 | 0.5246 | Yes |
| 21 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1589 | 1.620 | 0.5357 | Yes |
| 22 | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10862] | 1630 | 1.586 | 0.5479 | Yes |
| 23 | RDH10 | retinol dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:19975] | 1905 | 1.422 | 0.5524 | Yes |
| 24 | REEP3 | receptor accessory protein 3 [Source:HGNC Symbol;Acc:HGNC:23711] | 1933 | 1.402 | 0.5633 | Yes |
| 25 | C3 | complement C3 [Source:HGNC Symbol;Acc:HGNC:1318] | 1949 | 1.391 | 0.5746 | Yes |
| 26 | DUSP23 | dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480] | 1981 | 1.376 | 0.5852 | Yes |
| 27 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 2040 | 1.376 | 0.5952 | Yes |
| 28 | TNIP3 | TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315] | 2522 | 1.153 | 0.5918 | Yes |
| 29 | MED24 | mediator complex subunit 24 [Source:HGNC Symbol;Acc:HGNC:22963] | 2533 | 1.148 | 0.6011 | Yes |
| 30 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 2800 | 1.023 | 0.6025 | Yes |
| 31 | C15orf48 | chromosome 15 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29898] | 2801 | 1.022 | 0.6110 | Yes |
| 32 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 2910 | 0.974 | 0.6162 | Yes |
| 33 | SAT1 | spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540] | 3619 | 0.720 | 0.6031 | No |
| 34 | TMEM165 | transmembrane protein 165 [Source:HGNC Symbol;Acc:HGNC:30760] | 3884 | 0.647 | 0.6014 | No |
| 35 | KDR | kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307] | 4987 | 0.344 | 0.5744 | No |
| 36 | CSTB | cystatin B [Source:HGNC Symbol;Acc:HGNC:2482] | 5058 | 0.322 | 0.5752 | No |
| 37 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6444 | 0.000 | 0.5378 | No |
| 38 | MUCL1 | mucin like 1 [Source:HGNC Symbol;Acc:HGNC:30588] | 6540 | 0.000 | 0.5352 | No |
| 39 | DEFB4A | defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] | 7252 | 0.000 | 0.5160 | No |
| 40 | WFDC2 | WAP four-disulfide core domain 2 [Source:HGNC Symbol;Acc:HGNC:15939] | 8247 | 0.000 | 0.4891 | No |
| 41 | PROM1 | prominin 1 [Source:HGNC Symbol;Acc:HGNC:9454] | 8365 | 0.000 | 0.4859 | No |
| 42 | S100A9 | S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499] | 8653 | 0.000 | 0.4781 | No |
| 43 | CRISP3 | cysteine rich secretory protein 3 [Source:HGNC Symbol;Acc:HGNC:16904] | 9231 | 0.000 | 0.4625 | No |
| 44 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9336 | 0.000 | 0.4597 | No |
| 45 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9530 | 0.000 | 0.4545 | No |
| 46 | ADAM28 | ADAM metallopeptidase domain 28 [Source:HGNC Symbol;Acc:HGNC:206] | 9771 | 0.000 | 0.4480 | No |
| 47 | HS3ST1 | heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] | 10064 | 0.000 | 0.4401 | No |
| 48 | CYP2F1 | cytochrome P450 family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:2632] | 10434 | 0.000 | 0.4301 | No |
| 49 | KLK10 | kallikrein related peptidase 10 [Source:HGNC Symbol;Acc:HGNC:6358] | 10539 | 0.000 | 0.4273 | No |
| 50 | KLK11 | kallikrein related peptidase 11 [Source:HGNC Symbol;Acc:HGNC:6359] | 10540 | 0.000 | 0.4273 | No |
| 51 | KLK12 | kallikrein related peptidase 12 [Source:HGNC Symbol;Acc:HGNC:6360] | 10541 | 0.000 | 0.4273 | No |
| 52 | CX3CL1 | C-X3-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:10647] | 10819 | 0.000 | 0.4198 | No |
| 53 | LCN2 | lipocalin 2 [Source:HGNC Symbol;Acc:HGNC:6526] | 11009 | 0.000 | 0.4147 | No |
| 54 | SLC26A4 | solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818] | 11255 | 0.000 | 0.4081 | No |
| 55 | TSPAN8 | tetraspanin 8 [Source:HGNC Symbol;Acc:HGNC:11855] | 11610 | 0.000 | 0.3985 | No |
| 56 | AKR1C1 | aldo-keto reductase family 1 member C1 [Source:HGNC Symbol;Acc:HGNC:384] | 11651 | 0.000 | 0.3974 | No |
| 57 | AKR1C2 | aldo-keto reductase family 1 member C2 [Source:HGNC Symbol;Acc:HGNC:385] | 11653 | 0.000 | 0.3974 | No |
| 58 | S100P | S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504] | 11763 | 0.000 | 0.3944 | No |
| 59 | BACE2 | beta-secretase 2 [Source:HGNC Symbol;Acc:HGNC:934] | 11830 | 0.000 | 0.3927 | No |
| 60 | IGFBP3 | insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] | 11881 | 0.000 | 0.3913 | No |
| 61 | ATP12A | ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] | 12231 | 0.000 | 0.3819 | No |
| 62 | MSMB | microseminoprotein beta [Source:HGNC Symbol;Acc:HGNC:7372] | 12441 | 0.000 | 0.3762 | No |
| 63 | TNFSF10 | TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925] | 12480 | 0.000 | 0.3752 | No |
| 64 | VMO1 | vitelline membrane outer layer 1 homolog [Source:HGNC Symbol;Acc:HGNC:30387] | 12528 | 0.000 | 0.3739 | No |
| 65 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12848 | 0.000 | 0.3653 | No |
| 66 | MUC4 | mucin 4, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7514] | 12875 | 0.000 | 0.3646 | No |
| 67 | LINC00342 | long intergenic non-protein coding RNA 342 [Source:HGNC Symbol;Acc:HGNC:42470] | 13071 | 0.000 | 0.3593 | No |
| 68 | ZG16B | zymogen granule protein 16B [Source:HGNC Symbol;Acc:HGNC:30456] | 13348 | 0.000 | 0.3518 | No |
| 69 | RASD1 | ras related dexamethasone induced 1 [Source:HGNC Symbol;Acc:HGNC:15828] | 14453 | 0.000 | 0.3220 | No |
| 70 | TMC5 | transmembrane channel like 5 [Source:HGNC Symbol;Acc:HGNC:22999] | 14519 | 0.000 | 0.3202 | No |
| 71 | TMEM45A | transmembrane protein 45A [Source:HGNC Symbol;Acc:HGNC:25480] | 14874 | 0.000 | 0.3106 | No |
| 72 | CDC42EP5 | CDC42 effector protein 5 [Source:HGNC Symbol;Acc:HGNC:17408] | 16162 | 0.000 | 0.2758 | No |
| 73 | BPIFA1 | BPI fold containing family A member 1 [Source:HGNC Symbol;Acc:HGNC:15749] | 17617 | 0.000 | 0.2365 | No |
| 74 | BPIFB1 | BPI fold containing family B member 1 [Source:HGNC Symbol;Acc:HGNC:16108] | 17668 | 0.000 | 0.2351 | No |
| 75 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 17822 | 0.000 | 0.2310 | No |
| 76 | ANKRD36C | ankyrin repeat domain 36C [Source:HGNC Symbol;Acc:HGNC:32946] | 17875 | 0.000 | 0.2296 | No |
| 77 | HILPDA | hypoxia inducible lipid droplet associated [Source:HGNC Symbol;Acc:HGNC:28859] | 17928 | 0.000 | 0.2282 | No |
| 78 | HLA-DQA2 | major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:HGNC:4943] | 18447 | 0.000 | 0.2142 | No |
| 79 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942] | 18448 | 0.000 | 0.2142 | No |
| 80 | LTF | lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720] | 18800 | 0.000 | 0.2047 | No |
| 81 | MMP7 | matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174] | 19172 | 0.000 | 0.1946 | No |
| 82 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19524 | 0.000 | 0.1851 | No |
| 83 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19528 | 0.000 | 0.1851 | No |
| 84 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19537 | 0.000 | 0.1848 | No |
| 85 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19539 | 0.000 | 0.1848 | No |
| 86 | SMIM31 | small integral membrane protein 31 [Source:HGNC Symbol;Acc:HGNC:49638] | 19796 | 0.000 | 0.1779 | No |
| 87 | HSD17B2 | hydroxysteroid 17-beta dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:5211] | 19862 | 0.000 | 0.1761 | No |
| 88 | PI3 | peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947] | 20102 | 0.000 | 0.1697 | No |
| 89 | SCGB3A1 | secretoglobin family 3A member 1 [Source:HGNC Symbol;Acc:HGNC:18384] | 20635 | 0.000 | 0.1553 | No |
| 90 | SCGB1A1 | secretoglobin family 1A member 1 [Source:HGNC Symbol;Acc:HGNC:12523] | 21355 | 0.000 | 0.1358 | No |
| 91 | RARRES1 | retinoic acid receptor responder 1 [Source:HGNC Symbol;Acc:HGNC:9867] | 21498 | 0.000 | 0.1320 | No |
| 92 | CRYM | crystallin mu [Source:HGNC Symbol;Acc:HGNC:2418] | 21572 | 0.000 | 0.1300 | No |
| 93 | MUC5B | mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516] | 21580 | 0.000 | 0.1298 | No |
| 94 | SAA2 | serum amyloid A2 [Source:HGNC Symbol;Acc:HGNC:10514] | 21895 | 0.000 | 0.1213 | No |
| 95 | TFPI2 | tissue factor pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11761] | 22147 | 0.000 | 0.1145 | No |
| 96 | SLPI | secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092] | 22443 | 0.000 | 0.1066 | No |
| 97 | SLC4A4 | solute carrier family 4 member 4 [Source:HGNC Symbol;Acc:HGNC:11030] | 22641 | 0.000 | 0.1012 | No |
| 98 | RIMS1 | regulating synaptic membrane exocytosis 1 [Source:HGNC Symbol;Acc:HGNC:17282] | 22719 | 0.000 | 0.0991 | No |
| 99 | ALDH1A3 | aldehyde dehydrogenase 1 family member A3 [Source:HGNC Symbol;Acc:HGNC:409] | 23001 | 0.000 | 0.0915 | No |
| 100 | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 23050 | 0.000 | 0.0902 | No |
| 101 | AZGP1 | alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:HGNC:910] | 24064 | 0.000 | 0.0628 | No |
| 102 | FCGBP | Fc fragment of IgG binding protein [Source:HGNC Symbol;Acc:HGNC:13572] | 24133 | 0.000 | 0.0610 | No |
| 103 | IDO1 | indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] | 24922 | 0.000 | 0.0397 | No |
| 104 | TFF3 | trefoil factor 3 [Source:HGNC Symbol;Acc:HGNC:11757] | 25451 | 0.000 | 0.0254 | No |
| 105 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 27027 | 0.000 | -0.0172 | No |
| 106 | PIGR | polymeric immunoglobulin receptor [Source:HGNC Symbol;Acc:HGNC:8968] | 27803 | 0.000 | -0.0382 | No |
| 107 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27961 | 0.000 | -0.0424 | No |
| 108 | XBP1 | X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801] | 29189 | -0.218 | -0.0738 | No |
| 109 | SRD5A3 | steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] | 29266 | -0.234 | -0.0739 | No |
| 110 | RPS26 | ribosomal protein S26 [Source:HGNC Symbol;Acc:HGNC:10414] | 30513 | -0.451 | -0.1038 | No |
| 111 | CTSB | cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527] | 31379 | -0.697 | -0.1214 | No |
| 112 | HIPK2 | homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402] | 32006 | -0.875 | -0.1310 | No |
| 113 | LAG3 | lymphocyte activating 3 [Source:HGNC Symbol;Acc:HGNC:6476] | 32129 | -0.915 | -0.1267 | No |
| 114 | STT3B | STT3 oligosaccharyltransferase complex catalytic subunit B [Source:HGNC Symbol;Acc:HGNC:30611] | 33088 | -1.237 | -0.1422 | No |
| 115 | SLC26A2 | solute carrier family 26 member 2 [Source:HGNC Symbol;Acc:HGNC:10994] | 33608 | -1.439 | -0.1442 | No |
| 116 | INSR | insulin receptor [Source:HGNC Symbol;Acc:HGNC:6091] | 34255 | -1.744 | -0.1471 | No |
| 117 | RHOV | ras homolog family member V [Source:HGNC Symbol;Acc:HGNC:18313] | 34595 | -1.945 | -0.1400 | No |
| 118 | BID | BH3 interacting domain death agonist [Source:HGNC Symbol;Acc:HGNC:1050] | 34997 | -2.100 | -0.1333 | No |
| 119 | ERO1A | endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280] | 35325 | -2.321 | -0.1228 | No |
| 120 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 35596 | -2.521 | -0.1090 | No |
| 121 | ADM | adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259] | 36193 | -3.089 | -0.0993 | No |
| 122 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36422 | -3.377 | -0.0772 | No |
| 123 | SLC9A3R2 | SLC9A3 regulator 2 [Source:HGNC Symbol;Acc:HGNC:11076] | 36576 | -3.595 | -0.0513 | No |
| 124 | CBR3 | carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549] | 36694 | -3.808 | -0.0226 | No |
| 125 | SERPINF1 | serpin family F member 1 [Source:HGNC Symbol;Acc:HGNC:8824] | 36790 | -3.987 | 0.0081 | No |
