Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ZHONG_PFC_C2_UNKNOWN_NPC |
| Enrichment Score (ES) | -0.80424833 |
| Normalized Enrichment Score (NES) | -1.6693239 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011555783 |
| FWER p-Value | 0.015 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3538 | 0.752 | -0.0888 | No |
| 2 | KDM4A | lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978] | 4070 | 0.585 | -0.0978 | No |
| 3 | CNOT7 | CCR4-NOT transcription complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:14101] | 5205 | 0.285 | -0.1258 | No |
| 4 | TUBB6 | tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776] | 6234 | 0.036 | -0.1533 | No |
| 5 | CALB2 | calbindin 2 [Source:HGNC Symbol;Acc:HGNC:1435] | 8876 | 0.000 | -0.2246 | No |
| 6 | AC091057.1 | OTU deubiquitinase 7A pseudogene [Source:NCBI gene (formerly Entrezgene);Acc:100288637] | 12862 | 0.000 | -0.3323 | No |
| 7 | NDST4 | N-deacetylase and N-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:20779] | 13587 | 0.000 | -0.3519 | No |
| 8 | DNALI1 | dynein axonemal light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:14353] | 17898 | 0.000 | -0.4683 | No |
| 9 | AMBN | ameloblastin [Source:HGNC Symbol;Acc:HGNC:452] | 21736 | 0.000 | -0.5720 | No |
| 10 | MFAP2 | microfibril associated protein 2 [Source:HGNC Symbol;Acc:HGNC:7033] | 22816 | 0.000 | -0.6011 | No |
| 11 | ZNF649 | zinc finger protein 649 [Source:HGNC Symbol;Acc:HGNC:25741] | 26365 | 0.000 | -0.6970 | No |
| 12 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 28881 | -0.144 | -0.7636 | No |
| 13 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 28890 | -0.146 | -0.7625 | No |
| 14 | TROAP | trophinin associated protein [Source:HGNC Symbol;Acc:HGNC:12327] | 29255 | -0.232 | -0.7702 | No |
| 15 | PIF1 | PIF1 5'-to-3' DNA helicase [Source:HGNC Symbol;Acc:HGNC:26220] | 29274 | -0.237 | -0.7686 | No |
| 16 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 29461 | -0.290 | -0.7709 | No |
| 17 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 29943 | -0.320 | -0.7810 | No |
| 18 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 30121 | -0.351 | -0.7826 | No |
| 19 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 30420 | -0.426 | -0.7868 | No |
| 20 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 30483 | -0.442 | -0.7845 | No |
| 21 | TRIM59 | tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834] | 30924 | -0.566 | -0.7912 | No |
| 22 | ITCH | itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890] | 30967 | -0.580 | -0.7871 | No |
| 23 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 31154 | -0.630 | -0.7864 | No |
| 24 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31203 | -0.642 | -0.7819 | No |
| 25 | RANGAP1 | Ran GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9854] | 32032 | -0.884 | -0.7962 | Yes |
| 26 | ARL6IP1 | ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697] | 32155 | -0.923 | -0.7911 | Yes |
| 27 | REEP4 | receptor accessory protein 4 [Source:HGNC Symbol;Acc:HGNC:26176] | 32255 | -0.955 | -0.7851 | Yes |
| 28 | LDHA | lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535] | 32546 | -1.031 | -0.7836 | Yes |
| 29 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 32593 | -1.049 | -0.7753 | Yes |
| 30 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 32612 | -1.058 | -0.7662 | Yes |
| 31 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 32628 | -1.064 | -0.7570 | Yes |
| 32 | NDE1 | nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619] | 32804 | -1.133 | -0.7514 | Yes |
| 33 | TUBA1C | tubulin alpha 1c [Source:HGNC Symbol;Acc:HGNC:20768] | 32929 | -1.175 | -0.7441 | Yes |
| 34 | ARHGAP11A | Rho GTPase activating protein 11A [Source:HGNC Symbol;Acc:HGNC:15783] | 33037 | -1.217 | -0.7359 | Yes |
| 35 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 33664 | -1.454 | -0.7397 | Yes |
| 36 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 33668 | -1.457 | -0.7265 | Yes |
| 37 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 33695 | -1.469 | -0.7139 | Yes |
| 38 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 33702 | -1.472 | -0.7007 | Yes |
| 39 | FAM83D | family with sequence similarity 83 member D [Source:HGNC Symbol;Acc:HGNC:16122] | 33707 | -1.475 | -0.6874 | Yes |
| 40 | CIT | citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985] | 33760 | -1.501 | -0.6752 | Yes |
| 41 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 33926 | -1.576 | -0.6653 | Yes |
| 42 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 34050 | -1.644 | -0.6537 | Yes |
| 43 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 34054 | -1.648 | -0.6388 | Yes |
| 44 | MIS18BP1 | MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190] | 34154 | -1.697 | -0.6261 | Yes |
| 45 | CKAP2L | cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877] | 34157 | -1.698 | -0.6108 | Yes |
| 46 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:20338] | 34193 | -1.716 | -0.5961 | Yes |
| 47 | CEP70 | centrosomal protein 70 [Source:HGNC Symbol;Acc:HGNC:29972] | 34412 | -1.831 | -0.5854 | Yes |
| 48 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 34458 | -1.861 | -0.5697 | Yes |
| 49 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 34479 | -1.876 | -0.5532 | Yes |
| 50 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 34869 | -2.020 | -0.5454 | Yes |
| 51 | GTSE1 | G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698] | 34979 | -2.090 | -0.5294 | Yes |
| 52 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35003 | -2.106 | -0.5109 | Yes |
| 53 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35009 | -2.109 | -0.4919 | Yes |
| 54 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 35034 | -2.123 | -0.4732 | Yes |
| 55 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 35057 | -2.142 | -0.4544 | Yes |
| 56 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35073 | -2.150 | -0.4353 | Yes |
| 57 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 35118 | -2.180 | -0.4167 | Yes |
| 58 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 35145 | -2.200 | -0.3974 | Yes |
| 59 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35199 | -2.244 | -0.3785 | Yes |
| 60 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 35206 | -2.250 | -0.3582 | Yes |
| 61 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 35334 | -2.329 | -0.3405 | Yes |
| 62 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 35350 | -2.341 | -0.3197 | Yes |
| 63 | DCXR | dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985] | 35399 | -2.377 | -0.2994 | Yes |
| 64 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 35551 | -2.485 | -0.2809 | Yes |
| 65 | MZT1 | mitotic spindle organizing protein 1 [Source:HGNC Symbol;Acc:HGNC:33830] | 35627 | -2.547 | -0.2598 | Yes |
| 66 | PHF19 | PHD finger protein 19 [Source:HGNC Symbol;Acc:HGNC:24566] | 35648 | -2.571 | -0.2370 | Yes |
| 67 | CDCA2 | cell division cycle associated 2 [Source:HGNC Symbol;Acc:HGNC:14623] | 35655 | -2.574 | -0.2138 | Yes |
| 68 | KNSTRN | kinetochore localized astrin (SPAG5) binding protein [Source:HGNC Symbol;Acc:HGNC:30767] | 35692 | -2.606 | -0.1911 | Yes |
| 69 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35902 | -2.735 | -0.1719 | Yes |
| 70 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36035 | -2.919 | -0.1490 | Yes |
| 71 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36044 | -2.930 | -0.1226 | Yes |
| 72 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 36077 | -2.964 | -0.0966 | Yes |
| 73 | CDC25B | cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726] | 36189 | -3.084 | -0.0716 | Yes |
| 74 | NEIL3 | nei like DNA glycosylase 3 [Source:HGNC Symbol;Acc:HGNC:24573] | 36237 | -3.134 | -0.0444 | Yes |
| 75 | SGO2 | shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812] | 36374 | -3.300 | -0.0181 | Yes |
| 76 | PSRC1 | proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472] | 36859 | -4.124 | 0.0062 | Yes |
