Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HALLMARK_INTERFERON_ALPHA_RESPONSE |
| Enrichment Score (ES) | 0.7704947 |
| Normalized Enrichment Score (NES) | 1.9074632 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 57 | 4.736 | 0.0251 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 67 | 4.644 | 0.0510 | Yes |
| 3 | ISG20 | interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] | 80 | 4.589 | 0.0765 | Yes |
| 4 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 110 | 4.400 | 0.1005 | Yes |
| 5 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 115 | 4.370 | 0.1250 | Yes |
| 6 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 118 | 4.359 | 0.1495 | Yes |
| 7 | USP18 | ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] | 129 | 4.309 | 0.1735 | Yes |
| 8 | HELZ2 | helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] | 153 | 4.179 | 0.1964 | Yes |
| 9 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 154 | 4.171 | 0.2199 | Yes |
| 10 | IFIH1 | interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] | 199 | 3.919 | 0.2408 | Yes |
| 11 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 217 | 3.860 | 0.2620 | Yes |
| 12 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 222 | 3.839 | 0.2836 | Yes |
| 13 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 226 | 3.827 | 0.3050 | Yes |
| 14 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 262 | 3.624 | 0.3245 | Yes |
| 15 | TRAFD1 | TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808] | 270 | 3.583 | 0.3445 | Yes |
| 16 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 271 | 3.577 | 0.3646 | Yes |
| 17 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 351 | 3.322 | 0.3812 | Yes |
| 18 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 409 | 3.191 | 0.3976 | Yes |
| 19 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 426 | 3.158 | 0.4149 | Yes |
| 20 | TRIM21 | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | 484 | 3.055 | 0.4306 | Yes |
| 21 | PROCR | protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452] | 629 | 2.769 | 0.4423 | Yes |
| 22 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 662 | 2.716 | 0.4567 | Yes |
| 23 | STAT2 | signal transducer and activator of transcription 2 [Source:HGNC Symbol;Acc:HGNC:11363] | 676 | 2.697 | 0.4716 | Yes |
| 24 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 702 | 2.635 | 0.4857 | Yes |
| 25 | UBA7 | ubiquitin like modifier activating enzyme 7 [Source:HGNC Symbol;Acc:HGNC:12471] | 711 | 2.616 | 0.5002 | Yes |
| 26 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 713 | 2.611 | 0.5149 | Yes |
| 27 | CASP8 | caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509] | 721 | 2.596 | 0.5293 | Yes |
| 28 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 742 | 2.557 | 0.5432 | Yes |
| 29 | IFITM3 | interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414] | 744 | 2.555 | 0.5575 | Yes |
| 30 | TRIM14 | tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283] | 829 | 2.408 | 0.5688 | Yes |
| 31 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 842 | 2.384 | 0.5819 | Yes |
| 32 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 843 | 2.382 | 0.5953 | Yes |
| 33 | PARP14 | poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232] | 897 | 2.279 | 0.6067 | Yes |
| 34 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 1029 | 2.158 | 0.6153 | Yes |
| 35 | ADAR | adenosine deaminase RNA specific [Source:HGNC Symbol;Acc:HGNC:225] | 1049 | 2.137 | 0.6269 | Yes |
| 36 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 1110 | 2.068 | 0.6369 | Yes |
| 37 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 1168 | 1.988 | 0.6465 | Yes |
| 38 | OGFR | opioid growth factor receptor [Source:HGNC Symbol;Acc:HGNC:15768] | 1224 | 1.932 | 0.6559 | Yes |
| 39 | IFITM2 | interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413] | 1259 | 1.891 | 0.6656 | Yes |
| 40 | IRF9 | interferon regulatory factor 9 [Source:HGNC Symbol;Acc:HGNC:6131] | 1363 | 1.809 | 0.6730 | Yes |
| 41 | TAP1 | transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] | 1515 | 1.672 | 0.6784 | Yes |
| 42 | MOV10 | Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200] | 1522 | 1.669 | 0.6876 | Yes |
| 43 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 1647 | 1.573 | 0.6931 | Yes |
| 44 | UBE2L6 | ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490] | 1664 | 1.559 | 0.7015 | Yes |
| 45 | CMTR1 | cap methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:21077] | 1716 | 1.525 | 0.7087 | Yes |
| 46 | PSME2 | proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569] | 1750 | 1.508 | 0.7163 | Yes |
| 47 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 1781 | 1.487 | 0.7238 | Yes |
| 48 | TDRD7 | tudor domain containing 7 [Source:HGNC Symbol;Acc:HGNC:30831] | 1838 | 1.457 | 0.7305 | Yes |
| 49 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 1883 | 1.434 | 0.7374 | Yes |
| 50 | TENT5A | terminal nucleotidyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:18345] | 1918 | 1.413 | 0.7444 | Yes |
| 51 | IFITM1 | interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] | 2040 | 1.376 | 0.7489 | Yes |
| 52 | TRIM26 | tripartite motif containing 26 [Source:HGNC Symbol;Acc:HGNC:12962] | 2144 | 1.375 | 0.7539 | Yes |
| 53 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 2157 | 1.369 | 0.7613 | Yes |
| 54 | PSMB8 | proteasome 20S subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545] | 2462 | 1.188 | 0.7597 | Yes |
| 55 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 2520 | 1.154 | 0.7647 | Yes |
| 56 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 2684 | 1.073 | 0.7663 | Yes |
| 57 | WARS1 | tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] | 2866 | 0.991 | 0.7670 | Yes |
| 58 | SP110 | SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401] | 3081 | 0.911 | 0.7663 | Yes |
| 59 | PSMA3 | proteasome 20S subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:9532] | 3234 | 0.856 | 0.7671 | Yes |
| 60 | TRIM5 | tripartite motif containing 5 [Source:HGNC Symbol;Acc:HGNC:16276] | 3283 | 0.842 | 0.7705 | Yes |
| 61 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 3569 | 0.742 | 0.7670 | No |
| 62 | CASP1 | caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499] | 3806 | 0.673 | 0.7644 | No |
| 63 | CD47 | CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682] | 3998 | 0.608 | 0.7626 | No |
| 64 | HLA-C | major histocompatibility complex, class I, C [Source:HGNC Symbol;Acc:HGNC:4933] | 4052 | 0.590 | 0.7645 | No |
| 65 | PSME1 | proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568] | 4165 | 0.557 | 0.7646 | No |
| 66 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 5213 | 0.283 | 0.7379 | No |
| 67 | PSMB9 | proteasome 20S subunit beta 9 [Source:HGNC Symbol;Acc:HGNC:9546] | 5685 | 0.170 | 0.7262 | No |
| 68 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 6193 | 0.046 | 0.7127 | No |
| 69 | SELL | selectin L [Source:HGNC Symbol;Acc:HGNC:10720] | 7227 | 0.000 | 0.6848 | No |
| 70 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8852 | 0.000 | 0.6409 | No |
| 71 | BATF2 | basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163] | 8979 | 0.000 | 0.6375 | No |
| 72 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9336 | 0.000 | 0.6279 | No |
| 73 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10588 | 0.000 | 0.5940 | No |
| 74 | IFI30 | IFI30 lysosomal thiol reductase [Source:HGNC Symbol;Acc:HGNC:5398] | 11591 | 0.000 | 0.5670 | No |
| 75 | BST2 | bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] | 12511 | 0.000 | 0.5421 | No |
| 76 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 13515 | 0.000 | 0.5150 | No |
| 77 | IL4R | interleukin 4 receptor [Source:HGNC Symbol;Acc:HGNC:6015] | 13929 | 0.000 | 0.5038 | No |
| 78 | IL7 | interleukin 7 [Source:HGNC Symbol;Acc:HGNC:6023] | 17758 | 0.000 | 0.4004 | No |
| 79 | CXCL11 | C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] | 18985 | 0.000 | 0.3672 | No |
| 80 | NMI | N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854] | 19404 | 0.000 | 0.3559 | No |
| 81 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 21677 | 0.000 | 0.2945 | No |
| 82 | RNF31 | ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031] | 29172 | -0.215 | 0.0931 | No |
| 83 | NCOA7 | nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081] | 29388 | -0.268 | 0.0888 | No |
| 84 | LPAR6 | lysophosphatidic acid receptor 6 [Source:HGNC Symbol;Acc:HGNC:15520] | 30812 | -0.529 | 0.0534 | No |
| 85 | ELF1 | E74 like ETS transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3316] | 31394 | -0.700 | 0.0416 | No |
| 86 | SLC25A28 | solute carrier family 25 member 28 [Source:HGNC Symbol;Acc:HGNC:23472] | 31818 | -0.823 | 0.0348 | No |
| 87 | IRF1 | interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116] | 31994 | -0.872 | 0.0350 | No |
| 88 | B2M | beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914] | 32512 | -1.025 | 0.0268 | No |
| 89 | NUB1 | negative regulator of ubiquitin like proteins 1 [Source:HGNC Symbol;Acc:HGNC:17623] | 32538 | -1.029 | 0.0319 | No |
| 90 | MVB12A | multivesicular body subunit 12A [Source:HGNC Symbol;Acc:HGNC:25153] | 32561 | -1.036 | 0.0371 | No |
| 91 | IRF2 | interferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117] | 32696 | -1.088 | 0.0396 | No |
| 92 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 32902 | -1.167 | 0.0407 | No |
| 93 | C1S | complement C1s [Source:HGNC Symbol;Acc:HGNC:1247] | 33995 | -1.617 | 0.0202 | No |
| 94 | CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase [Source:HGNC Symbol;Acc:HGNC:2158] | 34971 | -2.088 | 0.0056 | No |
| 95 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35491 | -2.438 | 0.0053 | No |
| 96 | GMPR | guanosine monophosphate reductase [Source:HGNC Symbol;Acc:HGNC:4376] | 36004 | -2.870 | 0.0077 | No |
| 97 | IL15 | interleukin 15 [Source:HGNC Symbol;Acc:HGNC:5977] | 36710 | -3.849 | 0.0103 | No |
