Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.554941 |
| Normalized Enrichment Score (NES) | 1.2843032 |
| Nominal p-value | 0.054166667 |
| FDR q-value | 0.08984728 |
| FWER p-Value | 0.277 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | MYC | MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553] | 81 | 4.587 | 0.0540 | Yes |
| 2 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 111 | 4.399 | 0.1071 | Yes |
| 3 | GRWD1 | glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270] | 546 | 2.912 | 0.1311 | Yes |
| 4 | RRP9 | ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829] | 682 | 2.684 | 0.1603 | Yes |
| 5 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 728 | 2.585 | 0.1908 | Yes |
| 6 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 890 | 2.292 | 0.2145 | Yes |
| 7 | UTP20 | UTP20 small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897] | 969 | 2.248 | 0.2400 | Yes |
| 8 | NOP16 | NOP16 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:26934] | 1072 | 2.105 | 0.2630 | Yes |
| 9 | NOP2 | NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867] | 1083 | 2.095 | 0.2884 | Yes |
| 10 | FARSA | phenylalanyl-tRNA synthetase subunit alpha [Source:HGNC Symbol;Acc:HGNC:3592] | 1174 | 1.974 | 0.3102 | Yes |
| 11 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 1340 | 1.831 | 0.3282 | Yes |
| 12 | BYSL | bystin like [Source:HGNC Symbol;Acc:HGNC:1157] | 1386 | 1.790 | 0.3489 | Yes |
| 13 | NIP7 | nucleolar pre-rRNA processing protein NIP7 [Source:HGNC Symbol;Acc:HGNC:24328] | 1691 | 1.541 | 0.3595 | Yes |
| 14 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 1714 | 1.526 | 0.3776 | Yes |
| 15 | MRTO4 | MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477] | 1718 | 1.525 | 0.3962 | Yes |
| 16 | HSPE1 | heat shock protein family E (Hsp10) member 1 [Source:HGNC Symbol;Acc:HGNC:5269] | 1754 | 1.504 | 0.4137 | Yes |
| 17 | PUS1 | pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:15508] | 1856 | 1.447 | 0.4287 | Yes |
| 18 | IMP4 | IMP U3 small nucleolar ribonucleoprotein 4 [Source:HGNC Symbol;Acc:HGNC:30856] | 1890 | 1.432 | 0.4454 | Yes |
| 19 | PPRC1 | PPARG related coactivator 1 [Source:HGNC Symbol;Acc:HGNC:30025] | 1945 | 1.392 | 0.4610 | Yes |
| 20 | TCOF1 | treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654] | 2259 | 1.305 | 0.4685 | Yes |
| 21 | SRM | spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296] | 2385 | 1.224 | 0.4802 | Yes |
| 22 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 2428 | 1.201 | 0.4937 | Yes |
| 23 | MYBBP1A | MYB binding protein 1a [Source:HGNC Symbol;Acc:HGNC:7546] | 2594 | 1.115 | 0.5030 | Yes |
| 24 | DDX18 | DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741] | 2622 | 1.104 | 0.5157 | Yes |
| 25 | PHB | prohibitin [Source:HGNC Symbol;Acc:HGNC:8912] | 2660 | 1.084 | 0.5280 | Yes |
| 26 | WDR43 | WD repeat domain 43 [Source:HGNC Symbol;Acc:HGNC:28945] | 2838 | 1.007 | 0.5356 | Yes |
| 27 | NOP56 | NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:15911] | 2845 | 1.006 | 0.5477 | Yes |
| 28 | MPHOSPH10 | M-phase phosphoprotein 10 [Source:HGNC Symbol;Acc:HGNC:7213] | 3424 | 0.794 | 0.5419 | Yes |
| 29 | HSPD1 | heat shock protein family D (Hsp60) member 1 [Source:HGNC Symbol;Acc:HGNC:5261] | 3437 | 0.787 | 0.5512 | Yes |
| 30 | LAS1L | LAS1 like ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:25726] | 3625 | 0.718 | 0.5549 | Yes |
| 31 | RCL1 | RNA terminal phosphate cyclase like 1 [Source:HGNC Symbol;Acc:HGNC:17687] | 3973 | 0.616 | 0.5531 | No |
| 32 | PES1 | pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8848] | 4180 | 0.551 | 0.5543 | No |
| 33 | AIMP2 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609] | 4516 | 0.467 | 0.5510 | No |
| 34 | TBRG4 | transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:HGNC:17443] | 4952 | 0.353 | 0.5436 | No |
| 35 | NOLC1 | nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608] | 4963 | 0.351 | 0.5476 | No |
| 36 | WDR74 | WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529] | 5140 | 0.301 | 0.5465 | No |
| 37 | GNL3 | G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931] | 5291 | 0.268 | 0.5458 | No |
| 38 | PRMT3 | protein arginine methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30163] | 5336 | 0.255 | 0.5477 | No |
| 39 | NOC4L | nucleolar complex associated 4 homolog [Source:HGNC Symbol;Acc:HGNC:28461] | 5506 | 0.216 | 0.5458 | No |
| 40 | PPAN | peter pan homolog [Source:HGNC Symbol;Acc:HGNC:9227] | 5911 | 0.120 | 0.5363 | No |
| 41 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 6004 | 0.097 | 0.5350 | No |
| 42 | TMEM97 | transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] | 6205 | 0.042 | 0.5302 | No |
| 43 | NPM1 | nucleophosmin 1 [Source:HGNC Symbol;Acc:HGNC:7910] | 28671 | -0.083 | -0.0754 | No |
| 44 | SUPV3L1 | Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471] | 29525 | -0.305 | -0.0947 | No |
| 45 | RABEPK | Rab9 effector protein with kelch motifs [Source:HGNC Symbol;Acc:HGNC:16896] | 30676 | -0.493 | -0.1198 | No |
| 46 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 31198 | -0.641 | -0.1260 | No |
| 47 | SLC29A2 | solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] | 32390 | -0.998 | -0.1459 | No |
| 48 | CDK4 | cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773] | 32564 | -1.037 | -0.1379 | No |
| 49 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 32612 | -1.058 | -0.1262 | No |
| 50 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21034] | 33816 | -1.530 | -0.1399 | No |
| 51 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 33849 | -1.543 | -0.1219 | No |
| 52 | TFB2M | transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:18559] | 33875 | -1.546 | -0.1036 | No |
| 53 | EXOSC5 | exosome component 5 [Source:HGNC Symbol;Acc:HGNC:24662] | 33961 | -1.598 | -0.0863 | No |
| 54 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34493 | -1.883 | -0.0776 | No |
| 55 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858] | 35530 | -2.472 | -0.0753 | No |
| 56 | CBX3 | chromobox 3 [Source:HGNC Symbol;Acc:HGNC:1553] | 35784 | -2.687 | -0.0492 | No |
| 57 | SORD | sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184] | 36422 | -3.377 | -0.0250 | No |
| 58 | UNG | uracil DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:12572] | 36532 | -3.511 | 0.0151 | No |
