Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_PANCREAS_BETA_CELLS |
| Enrichment Score (ES) | -0.6961428 |
| Normalized Enrichment Score (NES) | -1.3381797 |
| Nominal p-value | 0.06534091 |
| FDR q-value | 0.1454381 |
| FWER p-Value | 0.552 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SRP9 | signal recognition particle 9 [Source:HGNC Symbol;Acc:HGNC:11304] | 1867 | 1.442 | 0.0146 | No |
| 2 | SRPRB | SRP receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:24085] | 2680 | 1.075 | 0.0412 | No |
| 3 | ELP4 | elongator acetyltransferase complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:1171] | 4384 | 0.499 | 0.0178 | No |
| 4 | SRP14 | signal recognition particle 14 [Source:HGNC Symbol;Acc:HGNC:11299] | 4786 | 0.398 | 0.0249 | No |
| 5 | PAK3 | p21 (RAC1) activated kinase 3 [Source:HGNC Symbol;Acc:HGNC:8592] | 4872 | 0.375 | 0.0395 | No |
| 6 | SPCS1 | signal peptidase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:23401] | 5465 | 0.225 | 0.0337 | No |
| 7 | SCGN | secretagogin, EF-hand calcium binding protein [Source:HGNC Symbol;Acc:HGNC:16941] | 6583 | 0.000 | 0.0035 | No |
| 8 | CHGA | chromogranin A [Source:HGNC Symbol;Acc:HGNC:1929] | 10620 | 0.000 | -0.1054 | No |
| 9 | G6PC2 | glucose-6-phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:28906] | 12421 | 0.000 | -0.1540 | No |
| 10 | SST | somatostatin [Source:HGNC Symbol;Acc:HGNC:11329] | 12471 | 0.000 | -0.1553 | No |
| 11 | SYT13 | synaptotagmin 13 [Source:HGNC Symbol;Acc:HGNC:14962] | 13762 | 0.000 | -0.1901 | No |
| 12 | PAX4 | paired box 4 [Source:HGNC Symbol;Acc:HGNC:8618] | 14927 | 0.000 | -0.2215 | No |
| 13 | DCX | doublecortin [Source:HGNC Symbol;Acc:HGNC:2714] | 16033 | 0.000 | -0.2514 | No |
| 14 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16273 | 0.000 | -0.2578 | No |
| 15 | PCSK1 | proprotein convertase subtilisin/kexin type 1 [Source:HGNC Symbol;Acc:HGNC:8743] | 16274 | 0.000 | -0.2578 | No |
| 16 | GCG | glucagon [Source:HGNC Symbol;Acc:HGNC:4191] | 16952 | 0.000 | -0.2761 | No |
| 17 | GCK | glucokinase [Source:HGNC Symbol;Acc:HGNC:4195] | 16954 | 0.000 | -0.2761 | No |
| 18 | HNF1A | HNF1 homeobox A [Source:HGNC Symbol;Acc:HGNC:11621] | 17634 | 0.000 | -0.2944 | No |
| 19 | INS | insulin [Source:HGNC Symbol;Acc:HGNC:6081] | 17784 | 0.000 | -0.2985 | No |
| 20 | DPP4 | dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009] | 17984 | 0.000 | -0.3038 | No |
| 21 | NKX2-2 | NK2 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7835] | 19276 | 0.000 | -0.3387 | No |
| 22 | IAPP | islet amyloid polypeptide [Source:HGNC Symbol;Acc:HGNC:5329] | 19328 | 0.000 | -0.3400 | No |
| 23 | NEUROD1 | neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:7762] | 19334 | 0.000 | -0.3402 | No |
| 24 | NEUROG3 | neurogenin 3 [Source:HGNC Symbol;Acc:HGNC:13806] | 19452 | 0.000 | -0.3433 | No |
| 25 | FOXA2 | forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022] | 20778 | 0.000 | -0.3791 | No |
| 26 | NKX6-1 | NK6 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7839] | 25350 | 0.000 | -0.5025 | No |
| 27 | PDX1 | pancreatic and duodenal homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6107] | 26211 | 0.000 | -0.5257 | No |
| 28 | INSM1 | INSM transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:6090] | 26867 | 0.000 | -0.5434 | No |
| 29 | ISL1 | ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132] | 27085 | 0.000 | -0.5492 | No |
| 30 | SLC2A2 | solute carrier family 2 member 2 [Source:HGNC Symbol;Acc:HGNC:11006] | 28325 | 0.000 | -0.5827 | No |
| 31 | ABCC8 | ATP binding cassette subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:59] | 28338 | 0.000 | -0.5830 | No |
| 32 | SEC11A | SEC11 homolog A, signal peptidase complex subunit [Source:HGNC Symbol;Acc:HGNC:17718] | 28863 | -0.139 | -0.5909 | No |
| 33 | STXBP1 | syntaxin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11444] | 28944 | -0.160 | -0.5858 | No |
| 34 | PKLR | pyruvate kinase L/R [Source:HGNC Symbol;Acc:HGNC:9020] | 33032 | -1.216 | -0.6413 | Yes |
| 35 | AKT3 | AKT serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:393] | 34130 | -1.685 | -0.5949 | Yes |
| 36 | VDR | vitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679] | 34840 | -2.005 | -0.5237 | Yes |
| 37 | LMO2 | LIM domain only 2 [Source:HGNC Symbol;Acc:HGNC:6642] | 35094 | -2.159 | -0.4331 | Yes |
| 38 | MAFB | MAF bZIP transcription factor B [Source:HGNC Symbol;Acc:HGNC:6408] | 35687 | -2.603 | -0.3318 | Yes |
| 39 | PAX6 | paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620] | 36572 | -3.588 | -0.1939 | Yes |
| 40 | FOXO1 | forkhead box O1 [Source:HGNC Symbol;Acc:HGNC:3819] | 37006 | -4.609 | 0.0023 | Yes |
