Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_GAQ |
| GeneSet | HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY |
| Enrichment Score (ES) | 0.457234 |
| Normalized Enrichment Score (NES) | 1.0374143 |
| Nominal p-value | 0.35390946 |
| FDR q-value | 0.4041863 |
| FWER p-Value | 0.918 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 371 | 3.286 | 0.0500 | Yes |
| 2 | TXNRD1 | thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437] | 420 | 3.167 | 0.1066 | Yes |
| 3 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 541 | 2.921 | 0.1567 | Yes |
| 4 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 635 | 2.763 | 0.2047 | Yes |
| 5 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 667 | 2.711 | 0.2534 | Yes |
| 6 | GCLM | glutamate-cysteine ligase modifier subunit [Source:HGNC Symbol;Acc:HGNC:4312] | 1014 | 2.184 | 0.2840 | Yes |
| 7 | SELENOS | selenoprotein S [Source:HGNC Symbol;Acc:HGNC:30396] | 1460 | 1.716 | 0.3034 | Yes |
| 8 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 1713 | 1.526 | 0.3245 | Yes |
| 9 | SRXN1 | sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132] | 1744 | 1.509 | 0.3512 | Yes |
| 10 | MSRA | methionine sulfoxide reductase A [Source:HGNC Symbol;Acc:HGNC:7377] | 1794 | 1.480 | 0.3770 | Yes |
| 11 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1849 | 1.450 | 0.4020 | Yes |
| 12 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 1974 | 1.376 | 0.4238 | Yes |
| 13 | PRNP | prion protein [Source:HGNC Symbol;Acc:HGNC:9449] | 2495 | 1.172 | 0.4312 | Yes |
| 14 | PRDX1 | peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] | 2580 | 1.125 | 0.4495 | Yes |
| 15 | G6PD | glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] | 3014 | 0.937 | 0.4549 | Yes |
| 16 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Source:HGNC Symbol;Acc:HGNC:17955] | 3457 | 0.781 | 0.4572 | Yes |
| 17 | SCAF4 | SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304] | 4319 | 0.517 | 0.4434 | No |
| 18 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434] | 4951 | 0.354 | 0.4329 | No |
| 19 | PRDX2 | peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353] | 4991 | 0.343 | 0.4381 | No |
| 20 | EGLN2 | egl-9 family hypoxia inducible factor 2 [Source:HGNC Symbol;Acc:HGNC:14660] | 5040 | 0.328 | 0.4428 | No |
| 21 | ATOX1 | antioxidant 1 copper chaperone [Source:HGNC Symbol;Acc:HGNC:798] | 5179 | 0.291 | 0.4444 | No |
| 22 | GSR | glutathione-disulfide reductase [Source:HGNC Symbol;Acc:HGNC:4623] | 5437 | 0.234 | 0.4417 | No |
| 23 | STK25 | serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404] | 6254 | 0.031 | 0.4202 | No |
| 24 | TXNRD2 | thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155] | 6343 | 0.009 | 0.4180 | No |
| 25 | GPX3 | glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555] | 9530 | 0.000 | 0.3320 | No |
| 26 | MGST1 | microsomal glutathione S-transferase 1 [Source:HGNC Symbol;Acc:HGNC:7061] | 11967 | 0.000 | 0.2663 | No |
| 27 | PDLIM1 | PDZ and LIM domain 1 [Source:HGNC Symbol;Acc:HGNC:2067] | 17785 | 0.000 | 0.1092 | No |
| 28 | IPCEF1 | interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204] | 17970 | 0.000 | 0.1043 | No |
| 29 | MPO | myeloperoxidase [Source:HGNC Symbol;Acc:HGNC:7218] | 19097 | 0.000 | 0.0739 | No |
| 30 | NDUFB4 | NADH:ubiquinone oxidoreductase subunit B4 [Source:HGNC Symbol;Acc:HGNC:7699] | 27937 | 0.000 | -0.1648 | No |
| 31 | HHEX | hematopoietically expressed homeobox [Source:HGNC Symbol;Acc:HGNC:4901] | 28609 | -0.065 | -0.1817 | No |
| 32 | FTL | ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999] | 28711 | -0.097 | -0.1826 | No |
| 33 | GCLC | glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311] | 30379 | -0.412 | -0.2201 | No |
| 34 | FES | FES proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3657] | 30602 | -0.475 | -0.2174 | No |
| 35 | PTPA | protein phosphatase 2 phosphatase activator [Source:HGNC Symbol;Acc:HGNC:9308] | 30651 | -0.485 | -0.2098 | No |
| 36 | SOD1 | superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179] | 31017 | -0.594 | -0.2088 | No |
| 37 | HMOX2 | heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014] | 31689 | -0.788 | -0.2126 | No |
| 38 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 32040 | -0.887 | -0.2058 | No |
| 39 | GLRX2 | glutaredoxin 2 [Source:HGNC Symbol;Acc:HGNC:16065] | 32334 | -0.979 | -0.1958 | No |
| 40 | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2 [Source:HGNC Symbol;Acc:HGNC:7708] | 32370 | -0.990 | -0.1787 | No |
| 41 | PRDX6 | peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753] | 32887 | -1.161 | -0.1714 | No |
| 42 | CAT | catalase [Source:HGNC Symbol;Acc:HGNC:1516] | 32898 | -1.165 | -0.1504 | No |
| 43 | NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690] | 33130 | -1.256 | -0.1337 | No |
| 44 | OXSR1 | oxidative stress responsive kinase 1 [Source:HGNC Symbol;Acc:HGNC:8508] | 33244 | -1.302 | -0.1129 | No |
| 45 | PFKP | phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878] | 34544 | -1.919 | -0.1129 | No |
| 46 | CDKN2D | cyclin dependent kinase inhibitor 2D [Source:HGNC Symbol;Acc:HGNC:1790] | 35358 | -2.345 | -0.0920 | No |
| 47 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 35412 | -2.388 | -0.0498 | No |
| 48 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 35469 | -2.416 | -0.0072 | No |
| 49 | LSP1 | lymphocyte specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707] | 35937 | -2.785 | 0.0311 | No |
