Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_GAQ_versus_WT_NA.Nof1.cls #WT_GAQ_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_GAQ_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | HALLMARK_SPERMATOGENESIS |
| Enrichment Score (ES) | -0.6169435 |
| Normalized Enrichment Score (NES) | -1.3674551 |
| Nominal p-value | 0.00591716 |
| FDR q-value | 0.12994139 |
| FWER p-Value | 0.428 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IL13RA2 | interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] | 548 | 2.909 | 0.0141 | No |
| 2 | ELOVL3 | ELOVL fatty acid elongase 3 [Source:HGNC Symbol;Acc:HGNC:18047] | 588 | 2.802 | 0.0410 | No |
| 3 | DPEP3 | dipeptidase 3 [Source:HGNC Symbol;Acc:HGNC:23029] | 694 | 2.650 | 0.0646 | No |
| 4 | PGS1 | phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:30029] | 2507 | 1.164 | 0.0271 | No |
| 5 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 2832 | 1.011 | 0.0284 | No |
| 6 | TCP11 | t-complex 11 [Source:HGNC Symbol;Acc:HGNC:11658] | 3165 | 0.882 | 0.0282 | No |
| 7 | TEKT2 | tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725] | 3227 | 0.858 | 0.0351 | No |
| 8 | TLE4 | TLE family member 4, transcriptional corepressor [Source:HGNC Symbol;Acc:HGNC:11840] | 3389 | 0.805 | 0.0388 | No |
| 9 | CCT6B | chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621] | 3810 | 0.671 | 0.0341 | No |
| 10 | ARL4A | ADP ribosylation factor like GTPase 4A [Source:HGNC Symbol;Acc:HGNC:695] | 4232 | 0.536 | 0.0281 | No |
| 11 | TSN | translin [Source:HGNC Symbol;Acc:HGNC:12379] | 4238 | 0.533 | 0.0332 | No |
| 12 | MAST2 | microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035] | 4322 | 0.516 | 0.0361 | No |
| 13 | STAM2 | signal transducing adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:11358] | 4552 | 0.455 | 0.0345 | No |
| 14 | PAPOLB | poly(A) polymerase beta [Source:HGNC Symbol;Acc:HGNC:15970] | 4801 | 0.394 | 0.0317 | No |
| 15 | NAA11 | N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125] | 4822 | 0.388 | 0.0350 | No |
| 16 | AGFG1 | ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:HGNC:5175] | 4862 | 0.380 | 0.0377 | No |
| 17 | IP6K1 | inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360] | 5075 | 0.316 | 0.0352 | No |
| 18 | ACTL7B | actin like 7B [Source:HGNC Symbol;Acc:HGNC:162] | 5166 | 0.292 | 0.0356 | No |
| 19 | CLGN | calmegin [Source:HGNC Symbol;Acc:HGNC:2060] | 5375 | 0.245 | 0.0325 | No |
| 20 | MLF1 | myeloid leukemia factor 1 [Source:HGNC Symbol;Acc:HGNC:7125] | 5475 | 0.224 | 0.0320 | No |
| 21 | RAD17 | RAD17 checkpoint clamp loader component [Source:HGNC Symbol;Acc:HGNC:9807] | 5866 | 0.130 | 0.0227 | No |
| 22 | CSNK2A2 | casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459] | 6020 | 0.093 | 0.0195 | No |
| 23 | CLPB | caseinolytic mitochondrial matrix peptidase chaperone subunit B [Source:HGNC Symbol;Acc:HGNC:30664] | 6186 | 0.049 | 0.0155 | No |
| 24 | PEBP1 | phosphatidylethanolamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8630] | 6223 | 0.038 | 0.0149 | No |
| 25 | CHFR | checkpoint with forkhead and ring finger domains [Source:HGNC Symbol;Acc:HGNC:20455] | 6339 | 0.011 | 0.0119 | No |
| 26 | SCG5 | secretogranin V [Source:HGNC Symbol;Acc:HGNC:10816] | 6596 | 0.000 | 0.0050 | No |
| 27 | SCG3 | secretogranin III [Source:HGNC Symbol;Acc:HGNC:13707] | 6598 | 0.000 | 0.0050 | No |
| 28 | ADCYAP1 | adenylate cyclase activating polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:241] | 7423 | 0.000 | -0.0173 | No |
| 29 | ART3 | ADP-ribosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:725] | 7531 | 0.000 | -0.0202 | No |
| 30 | CCNA1 | cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577] | 7641 | 0.000 | -0.0232 | No |
| 31 | ZC2HC1C | zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354] | 8361 | 0.000 | -0.0426 | No |
| 32 | HOXB1 | homeobox B1 [Source:HGNC Symbol;Acc:HGNC:5111] | 8932 | 0.000 | -0.0580 | No |
| 33 | ADAM2 | ADAM metallopeptidase domain 2 [Source:HGNC Symbol;Acc:HGNC:198] | 9012 | 0.000 | -0.0602 | No |
| 34 | ADAD1 | adenosine deaminase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30713] | 9165 | 0.000 | -0.0643 | No |
| 35 | CAMK4 | calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464] | 9187 | 0.000 | -0.0649 | No |
| 36 | CRISP2 | cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024] | 9229 | 0.000 | -0.0660 | No |
| 37 | NPY5R | neuropeptide Y receptor Y5 [Source:HGNC Symbol;Acc:HGNC:7958] | 9236 | 0.000 | -0.0661 | No |
| 38 | DMRT1 | doublesex and mab-3 related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:2934] | 9621 | 0.000 | -0.0765 | No |
| 39 | NEFH | neurofilament heavy [Source:HGNC Symbol;Acc:HGNC:7737] | 9736 | 0.000 | -0.0796 | No |
| 40 | GRM8 | glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600] | 10029 | 0.000 | -0.0875 | No |
| 41 | TULP2 | TUB like protein 2 [Source:HGNC Symbol;Acc:HGNC:12424] | 10207 | 0.000 | -0.0923 | No |
| 42 | CFTR | CF transmembrane conductance regulator [Source:HGNC Symbol;Acc:HGNC:1884] | 10238 | 0.000 | -0.0931 | No |
| 43 | LDHC | lactate dehydrogenase C [Source:HGNC Symbol;Acc:HGNC:6544] | 11196 | 0.000 | -0.1190 | No |
| 44 | PRM2 | protamine 2 [Source:HGNC Symbol;Acc:HGNC:9448] | 11669 | 0.000 | -0.1318 | No |
| 45 | SEPTIN4 | septin 4 [Source:HGNC Symbol;Acc:HGNC:9165] | 11856 | 0.000 | -0.1368 | No |
| 46 | JAM3 | junctional adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:15532] | 12217 | 0.000 | -0.1465 | No |
| 47 | GAD1 | glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] | 12551 | 0.000 | -0.1556 | No |
| 48 | THEG | theg spermatid protein [Source:HGNC Symbol;Acc:HGNC:13706] | 12773 | 0.000 | -0.1615 | No |
| 49 | TNP2 | transition protein 2 [Source:HGNC Symbol;Acc:HGNC:11952] | 15079 | 0.000 | -0.2239 | No |
| 50 | TNP1 | transition protein 1 [Source:HGNC Symbol;Acc:HGNC:11951] | 15081 | 0.000 | -0.2239 | No |
| 51 | HTR5A | 5-hydroxytryptamine receptor 5A [Source:HGNC Symbol;Acc:HGNC:5300] | 15614 | 0.000 | -0.2383 | No |
| 52 | CLVS1 | clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139] | 15740 | 0.000 | -0.2417 | No |
| 53 | MTNR1A | melatonin receptor 1A [Source:HGNC Symbol;Acc:HGNC:7463] | 15825 | 0.000 | -0.2440 | No |
| 54 | DCC | DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701] | 16022 | 0.000 | -0.2493 | No |
| 55 | GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [Source:HGNC Symbol;Acc:HGNC:24864] | 16502 | 0.000 | -0.2622 | No |
| 56 | AKAP4 | A-kinase anchoring protein 4 [Source:HGNC Symbol;Acc:HGNC:374] | 16658 | 0.000 | -0.2664 | No |
| 57 | DMC1 | DNA meiotic recombinase 1 [Source:HGNC Symbol;Acc:HGNC:2927] | 16924 | 0.000 | -0.2736 | No |
| 58 | TKTL1 | transketolase like 1 [Source:HGNC Symbol;Acc:HGNC:11835] | 17254 | 0.000 | -0.2825 | No |
| 59 | HBZ | hemoglobin subunit zeta [Source:HGNC Symbol;Acc:HGNC:4835] | 17301 | 0.000 | -0.2838 | No |
| 60 | SYCP1 | synaptonemal complex protein 1 [Source:HGNC Symbol;Acc:HGNC:11487] | 17895 | 0.000 | -0.2998 | No |
| 61 | DNAJB8 | DnaJ heat shock protein family (Hsp40) member B8 [Source:HGNC Symbol;Acc:HGNC:23699] | 18575 | 0.000 | -0.3182 | No |
| 62 | IL12RB2 | interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] | 19705 | 0.000 | -0.3487 | No |
| 63 | MEP1B | meprin A subunit beta [Source:HGNC Symbol;Acc:HGNC:7020] | 20323 | 0.000 | -0.3654 | No |
| 64 | ACRV1 | acrosomal vesicle protein 1 [Source:HGNC Symbol;Acc:HGNC:127] | 20530 | 0.000 | -0.3710 | No |
| 65 | TSSK2 | testis specific serine kinase 2 [Source:HGNC Symbol;Acc:HGNC:11401] | 21708 | 0.000 | -0.4028 | No |
| 66 | SNAP91 | synaptosome associated protein 91 [Source:HGNC Symbol;Acc:HGNC:14986] | 21841 | 0.000 | -0.4064 | No |
| 67 | CST8 | cystatin 8 [Source:HGNC Symbol;Acc:HGNC:2480] | 21879 | 0.000 | -0.4074 | No |
| 68 | OAZ3 | ornithine decarboxylase antizyme 3 [Source:HGNC Symbol;Acc:HGNC:8097] | 23051 | 0.000 | -0.4391 | No |
| 69 | ODF1 | outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113] | 23766 | 0.000 | -0.4584 | No |
| 70 | ZNRF4 | zinc and ring finger 4 [Source:HGNC Symbol;Acc:HGNC:17726] | 23806 | 0.000 | -0.4595 | No |
| 71 | DDX4 | DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700] | 23881 | 0.000 | -0.4615 | No |
| 72 | ACE | angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] | 24502 | 0.000 | -0.4783 | No |
| 73 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] | 25527 | 0.000 | -0.5060 | No |
| 74 | SHE | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] | 25645 | 0.000 | -0.5091 | No |
| 75 | YBX2 | Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948] | 27736 | 0.000 | -0.5657 | No |
| 76 | H1-6 | H1.6 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4720] | 27799 | 0.000 | -0.5674 | No |
| 77 | DDX25 | DEAD-box helicase 25 [Source:HGNC Symbol;Acc:HGNC:18698] | 28162 | 0.000 | -0.5772 | No |
| 78 | MAP7 | microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869] | 28245 | 0.000 | -0.5794 | No |
| 79 | SLC2A5 | solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010] | 28327 | 0.000 | -0.5816 | No |
| 80 | TALDO1 | transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559] | 28418 | -0.016 | -0.5839 | No |
| 81 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 28769 | -0.115 | -0.5922 | No |
| 82 | PIAS2 | protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311] | 28776 | -0.116 | -0.5912 | No |
| 83 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor [Source:HGNC Symbol;Acc:HGNC:16063] | 29214 | -0.223 | -0.6008 | No |
| 84 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 29220 | -0.226 | -0.5987 | No |
| 85 | PHKG2 | phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931] | 29490 | -0.296 | -0.6030 | No |
| 86 | NOS1 | nitric oxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:7872] | 29598 | -0.320 | -0.6027 | No |
| 87 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 29718 | -0.320 | -0.6027 | No |
| 88 | GSTM3 | glutathione S-transferase mu 3 [Source:HGNC Symbol;Acc:HGNC:4635] | 29970 | -0.320 | -0.6063 | No |
| 89 | ALOX15 | arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] | 30004 | -0.324 | -0.6040 | No |
| 90 | CHRM4 | cholinergic receptor muscarinic 4 [Source:HGNC Symbol;Acc:HGNC:1953] | 30187 | -0.370 | -0.6053 | No |
| 91 | BRAF | B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097] | 30486 | -0.442 | -0.6089 | No |
| 92 | PGK2 | phosphoglycerate kinase 2 [Source:HGNC Symbol;Acc:HGNC:8898] | 30784 | -0.521 | -0.6118 | Yes |
| 93 | SIRT1 | sirtuin 1 [Source:HGNC Symbol;Acc:HGNC:14929] | 30806 | -0.528 | -0.6071 | Yes |
| 94 | PRKAR2A | protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391] | 31076 | -0.612 | -0.6082 | Yes |
| 95 | COIL | coilin [Source:HGNC Symbol;Acc:HGNC:2184] | 31091 | -0.612 | -0.6025 | Yes |
| 96 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 31203 | -0.642 | -0.5991 | Yes |
| 97 | HSPA1L | heat shock protein family A (Hsp70) member 1 like [Source:HGNC Symbol;Acc:HGNC:5234] | 31275 | -0.659 | -0.5945 | Yes |
| 98 | TUBA3C | tubulin alpha 3c [Source:HGNC Symbol;Acc:HGNC:12408] | 31403 | -0.701 | -0.5909 | Yes |
| 99 | PSMG1 | proteasome assembly chaperone 1 [Source:HGNC Symbol;Acc:HGNC:3043] | 31667 | -0.780 | -0.5903 | Yes |
| 100 | PDHA2 | pyruvate dehydrogenase E1 subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:8807] | 31748 | -0.805 | -0.5844 | Yes |
| 101 | VDAC3 | voltage dependent anion channel 3 [Source:HGNC Symbol;Acc:HGNC:12674] | 31755 | -0.806 | -0.5766 | Yes |
| 102 | SPATA6 | spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309] | 32093 | -0.905 | -0.5767 | Yes |
| 103 | MTOR | mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942] | 32186 | -0.934 | -0.5699 | Yes |
| 104 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 32400 | -1.001 | -0.5656 | Yes |
| 105 | ZC3H14 | zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509] | 32578 | -1.041 | -0.5601 | Yes |
| 106 | IDE | insulin degrading enzyme [Source:HGNC Symbol;Acc:HGNC:5381] | 32590 | -1.046 | -0.5499 | Yes |
| 107 | PHF7 | PHD finger protein 7 [Source:HGNC Symbol;Acc:HGNC:18458] | 33175 | -1.274 | -0.5530 | Yes |
| 108 | POMC | proopiomelanocortin [Source:HGNC Symbol;Acc:HGNC:9201] | 33307 | -1.304 | -0.5436 | Yes |
| 109 | GSG1 | germ cell associated 1 [Source:HGNC Symbol;Acc:HGNC:19716] | 33435 | -1.360 | -0.5335 | Yes |
| 110 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 33668 | -1.457 | -0.5252 | Yes |
| 111 | PARP2 | poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272] | 33696 | -1.470 | -0.5113 | Yes |
| 112 | ZPBP | zona pellucida binding protein [Source:HGNC Symbol;Acc:HGNC:15662] | 33878 | -1.546 | -0.5008 | Yes |
| 113 | NF2 | neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773] | 34314 | -1.777 | -0.4949 | Yes |
| 114 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 34479 | -1.876 | -0.4807 | Yes |
| 115 | PACRG | parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152] | 34512 | -1.893 | -0.4627 | Yes |
| 116 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 34559 | -1.929 | -0.4447 | Yes |
| 117 | TNNI3 | troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947] | 34851 | -2.012 | -0.4325 | Yes |
| 118 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 34857 | -2.014 | -0.4126 | Yes |
| 119 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 35003 | -2.106 | -0.3955 | Yes |
| 120 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 35030 | -2.121 | -0.3751 | Yes |
| 121 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 35074 | -2.151 | -0.3548 | Yes |
| 122 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 35145 | -2.200 | -0.3348 | Yes |
| 123 | IFT88 | intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606] | 35186 | -2.235 | -0.3136 | Yes |
| 124 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 35199 | -2.244 | -0.2916 | Yes |
| 125 | NPHP1 | nephrocystin 1 [Source:HGNC Symbol;Acc:HGNC:7905] | 35255 | -2.276 | -0.2704 | Yes |
| 126 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 35269 | -2.283 | -0.2480 | Yes |
| 127 | HSPA4L | heat shock protein family A (Hsp70) member 4 like [Source:HGNC Symbol;Acc:HGNC:17041] | 35739 | -2.643 | -0.2344 | Yes |
| 128 | STRBP | spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462] | 35945 | -2.791 | -0.2121 | Yes |
| 129 | TOPBP1 | DNA topoisomerase II binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17008] | 35948 | -2.793 | -0.1843 | Yes |
| 130 | HSPA2 | heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235] | 36030 | -2.912 | -0.1575 | Yes |
| 131 | GMCL1 | germ cell-less 1, spermatogenesis associated [Source:HGNC Symbol;Acc:HGNC:23843] | 36079 | -2.966 | -0.1293 | Yes |
| 132 | PCSK4 | proprotein convertase subtilisin/kexin type 4 [Source:HGNC Symbol;Acc:HGNC:8746] | 36499 | -3.491 | -0.1058 | Yes |
| 133 | ACRBP | acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195] | 36642 | -3.720 | -0.0726 | Yes |
| 134 | RPL39L | ribosomal protein L39 like [Source:HGNC Symbol;Acc:HGNC:17094] | 36653 | -3.721 | -0.0358 | Yes |
| 135 | LPIN1 | lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] | 37047 | -4.778 | 0.0012 | Yes |
