Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | CROONQUIST_IL6_DEPRIVATION_DN |
| Enrichment Score (ES) | -0.7837235 |
| Normalized Enrichment Score (NES) | -1.6382216 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011997177 |
| FWER p-Value | 0.16 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 452 | 3.330 | 0.0038 | No |
| 2 | RRP12 | ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100] | 1781 | 1.584 | -0.0245 | No |
| 3 | ABHD5 | abhydrolase domain containing 5, lysophosphatidic acid acyltransferase [Source:HGNC Symbol;Acc:HGNC:21396] | 2333 | 1.214 | -0.0335 | No |
| 4 | GGH | gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] | 2590 | 1.095 | -0.0352 | No |
| 5 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3147 | 0.848 | -0.0461 | No |
| 6 | HMGA1 | high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010] | 3188 | 0.824 | -0.0432 | No |
| 7 | CDC25A | cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725] | 3201 | 0.821 | -0.0396 | No |
| 8 | SBNO2 | strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158] | 3346 | 0.761 | -0.0398 | No |
| 9 | PTPRC | protein tyrosine phosphatase receptor type C [Source:HGNC Symbol;Acc:HGNC:9666] | 3751 | 0.619 | -0.0478 | No |
| 10 | SNRPA1 | small nuclear ribonucleoprotein polypeptide A' [Source:HGNC Symbol;Acc:HGNC:11152] | 4594 | 0.341 | -0.0689 | No |
| 11 | ITM2A | integral membrane protein 2A [Source:HGNC Symbol;Acc:HGNC:6173] | 5230 | 0.162 | -0.0853 | No |
| 12 | DHFR | dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861] | 5554 | 0.153 | -0.0933 | No |
| 13 | AASS | aminoadipate-semialdehyde synthase [Source:HGNC Symbol;Acc:HGNC:17366] | 10347 | 0.000 | -0.2228 | No |
| 14 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12359 | 0.000 | -0.2771 | No |
| 15 | FRZB | frizzled related protein [Source:HGNC Symbol;Acc:HGNC:3959] | 16683 | 0.000 | -0.3940 | No |
| 16 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.5744 | No |
| 17 | MYRF | myelin regulatory factor [Source:HGNC Symbol;Acc:HGNC:1181] | 28628 | -0.135 | -0.7162 | No |
| 18 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7539 | No |
| 19 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30207 | -0.543 | -0.7537 | No |
| 20 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 30394 | -0.578 | -0.7559 | No |
| 21 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30578 | -0.627 | -0.7579 | No |
| 22 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.7769 | Yes |
| 23 | SPOUT1 | SPOUT domain containing methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26933] | 31487 | -0.890 | -0.7739 | Yes |
| 24 | GMPS | guanine monophosphate synthase [Source:HGNC Symbol;Acc:HGNC:4378] | 31715 | -0.966 | -0.7754 | Yes |
| 25 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 31736 | -0.972 | -0.7712 | Yes |
| 26 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 31758 | -0.979 | -0.7671 | Yes |
| 27 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 32023 | -1.073 | -0.7691 | Yes |
| 28 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.7672 | Yes |
| 29 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 32379 | -1.207 | -0.7675 | Yes |
| 30 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32455 | -1.235 | -0.7636 | Yes |
| 31 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 32548 | -1.271 | -0.7599 | Yes |
| 32 | SEPHS1 | selenophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:19685] | 33075 | -1.497 | -0.7669 | Yes |
| 33 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.7683 | Yes |
| 34 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 33975 | -1.818 | -0.7750 | Yes |
| 35 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.7679 | Yes |
| 36 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.7623 | Yes |
| 37 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34248 | -1.957 | -0.7547 | Yes |
| 38 | CHAF1A | chromatin assembly factor 1 subunit A [Source:HGNC Symbol;Acc:HGNC:1910] | 34259 | -1.967 | -0.7455 | Yes |
| 39 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 34381 | -2.017 | -0.7390 | Yes |
| 40 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.7350 | Yes |
| 41 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34638 | -2.171 | -0.7251 | Yes |
| 42 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.7184 | Yes |
| 43 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 34800 | -2.282 | -0.7075 | Yes |
| 44 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 34811 | -2.286 | -0.6967 | Yes |
| 45 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.6859 | Yes |
| 46 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 34863 | -2.322 | -0.6759 | Yes |
| 47 | H2BC11 | H2B clustered histone 11 [Source:HGNC Symbol;Acc:HGNC:4761] | 34891 | -2.343 | -0.6654 | Yes |
| 48 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.6548 | Yes |
| 49 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34947 | -2.382 | -0.6440 | Yes |
| 50 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 34952 | -2.382 | -0.6326 | Yes |
| 51 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.6238 | Yes |
| 52 | GALK1 | galactokinase 1 [Source:HGNC Symbol;Acc:HGNC:4118] | 35092 | -2.416 | -0.6132 | Yes |
| 53 | STIL | STIL centriolar assembly protein [Source:HGNC Symbol;Acc:HGNC:10879] | 35121 | -2.440 | -0.6022 | Yes |
| 54 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35122 | -2.440 | -0.5905 | Yes |
| 55 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 35152 | -2.473 | -0.5793 | Yes |
| 56 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35187 | -2.501 | -0.5682 | Yes |
| 57 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.5568 | Yes |
| 58 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35484 | -2.727 | -0.5509 | Yes |
| 59 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35504 | -2.750 | -0.5382 | Yes |
| 60 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35524 | -2.765 | -0.5254 | Yes |
| 61 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 35525 | -2.767 | -0.5120 | Yes |
| 62 | SPAG5 | sperm associated antigen 5 [Source:HGNC Symbol;Acc:HGNC:13452] | 35557 | -2.803 | -0.4994 | Yes |
| 63 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35559 | -2.806 | -0.4859 | Yes |
| 64 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35595 | -2.845 | -0.4732 | Yes |
| 65 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.4600 | Yes |
| 66 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.4464 | Yes |
| 67 | GPX4 | glutathione peroxidase 4 [Source:HGNC Symbol;Acc:HGNC:4556] | 35711 | -2.911 | -0.4344 | Yes |
| 68 | GALE | UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116] | 35756 | -2.954 | -0.4214 | Yes |
| 69 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 35783 | -2.979 | -0.4078 | Yes |
| 70 | TRAIP | TRAF interacting protein [Source:HGNC Symbol;Acc:HGNC:30764] | 35797 | -2.987 | -0.3937 | Yes |
| 71 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.3796 | Yes |
| 72 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35839 | -3.018 | -0.3659 | Yes |
| 73 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35911 | -3.088 | -0.3529 | Yes |
| 74 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35969 | -3.152 | -0.3393 | Yes |
| 75 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36011 | -3.197 | -0.3250 | Yes |
| 76 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36034 | -3.229 | -0.3100 | Yes |
| 77 | PTP4A3 | protein tyrosine phosphatase 4A3 [Source:HGNC Symbol;Acc:HGNC:9636] | 36043 | -3.241 | -0.2947 | Yes |
| 78 | KIF22 | kinesin family member 22 [Source:HGNC Symbol;Acc:HGNC:6391] | 36079 | -3.255 | -0.2799 | Yes |
| 79 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.2647 | Yes |
| 80 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36135 | -3.335 | -0.2495 | Yes |
| 81 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36199 | -3.393 | -0.2349 | Yes |
| 82 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.2187 | Yes |
| 83 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.2045 | Yes |
| 84 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36332 | -3.523 | -0.1882 | Yes |
| 85 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.1715 | Yes |
| 86 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 36365 | -3.555 | -0.1549 | Yes |
| 87 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.1407 | Yes |
| 88 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.1229 | Yes |
| 89 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.1065 | Yes |
| 90 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36607 | -3.868 | -0.0886 | Yes |
| 91 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36610 | -3.875 | -0.0700 | Yes |
| 92 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 36711 | -3.993 | -0.0535 | Yes |
| 93 | WEE1 | WEE1 G2 checkpoint kinase [Source:HGNC Symbol;Acc:HGNC:12761] | 36881 | -4.323 | -0.0372 | Yes |
| 94 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 36922 | -4.425 | -0.0170 | Yes |
| 95 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 36948 | -4.472 | 0.0038 | Yes |
