Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN |
| Enrichment Score (ES) | 0.8544215 |
| Normalized Enrichment Score (NES) | 2.0801575 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.8583563E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 5 | 4.992 | 0.0217 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 10 | 4.988 | 0.0434 | Yes |
| 3 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 16 | 4.973 | 0.0649 | Yes |
| 4 | ACOD1 | aconitate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:33904] | 22 | 4.970 | 0.0865 | Yes |
| 5 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 32 | 4.953 | 0.1079 | Yes |
| 6 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 37 | 4.938 | 0.1294 | Yes |
| 7 | PHLDA1 | pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933] | 68 | 4.819 | 0.1496 | Yes |
| 8 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 76 | 4.788 | 0.1704 | Yes |
| 9 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 78 | 4.783 | 0.1912 | Yes |
| 10 | DUSP2 | dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068] | 101 | 4.641 | 0.2109 | Yes |
| 11 | ODC1 | ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] | 109 | 4.595 | 0.2308 | Yes |
| 12 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 113 | 4.584 | 0.2507 | Yes |
| 13 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 116 | 4.554 | 0.2706 | Yes |
| 14 | SOCS3 | suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391] | 123 | 4.514 | 0.2901 | Yes |
| 15 | TRAF1 | TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031] | 135 | 4.460 | 0.3093 | Yes |
| 16 | SLFN12 | schlafen family member 12 [Source:HGNC Symbol;Acc:HGNC:25500] | 138 | 4.450 | 0.3287 | Yes |
| 17 | MARCKSL1 | MARCKS like 1 [Source:HGNC Symbol;Acc:HGNC:7142] | 163 | 4.316 | 0.3469 | Yes |
| 18 | ITGA5 | integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141] | 192 | 4.193 | 0.3645 | Yes |
| 19 | ADORA2B | adenosine A2b receptor [Source:HGNC Symbol;Acc:HGNC:264] | 209 | 4.148 | 0.3822 | Yes |
| 20 | DUSP1 | dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064] | 211 | 4.133 | 0.4002 | Yes |
| 21 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986] | 242 | 4.026 | 0.4170 | Yes |
| 22 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 266 | 3.940 | 0.4336 | Yes |
| 23 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 271 | 3.923 | 0.4506 | Yes |
| 24 | SLC11A1 | solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907] | 277 | 3.893 | 0.4675 | Yes |
| 25 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 285 | 3.875 | 0.4842 | Yes |
| 26 | NFKB1 | nuclear factor kappa B subunit 1 [Source:HGNC Symbol;Acc:HGNC:7794] | 289 | 3.842 | 0.5009 | Yes |
| 27 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 307 | 3.782 | 0.5170 | Yes |
| 28 | CD83 | CD83 molecule [Source:HGNC Symbol;Acc:HGNC:1703] | 323 | 3.706 | 0.5328 | Yes |
| 29 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 330 | 3.672 | 0.5487 | Yes |
| 30 | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205] | 359 | 3.593 | 0.5636 | Yes |
| 31 | SLFN12L | schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920] | 362 | 3.570 | 0.5791 | Yes |
| 32 | PDLIM7 | PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958] | 406 | 3.436 | 0.5930 | Yes |
| 33 | TAPBP | TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566] | 435 | 3.396 | 0.6071 | Yes |
| 34 | GLRX | glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330] | 438 | 3.391 | 0.6218 | Yes |
| 35 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 444 | 3.352 | 0.6363 | Yes |
| 36 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 452 | 3.330 | 0.6507 | Yes |
| 37 | CCL4L2 | C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066] | 485 | 3.257 | 0.6641 | Yes |
| 38 | CD14 | CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] | 501 | 3.205 | 0.6777 | Yes |
| 39 | PCDH7 | protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659] | 506 | 3.190 | 0.6915 | Yes |
| 40 | GADD45A | growth arrest and DNA damage inducible alpha [Source:HGNC Symbol;Acc:HGNC:4095] | 528 | 3.114 | 0.7045 | Yes |
| 41 | ACTG1 | actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144] | 535 | 3.104 | 0.7179 | Yes |
| 42 | SQSTM1 | sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280] | 539 | 3.098 | 0.7314 | Yes |
| 43 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 562 | 3.090 | 0.7443 | Yes |
| 44 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 571 | 3.068 | 0.7575 | Yes |
| 45 | IKBKE | inhibitor of nuclear factor kappa B kinase subunit epsilon [Source:HGNC Symbol;Acc:HGNC:14552] | 625 | 2.958 | 0.7690 | Yes |
| 46 | ETS2 | ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489] | 653 | 2.889 | 0.7809 | Yes |
| 47 | ERRFI1 | ERBB receptor feedback inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:18185] | 656 | 2.886 | 0.7934 | Yes |
| 48 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 763 | 2.669 | 0.8022 | Yes |
| 49 | SRPRA | SRP receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:11307] | 1012 | 2.316 | 0.8056 | Yes |
| 50 | IL18RAP | interleukin 18 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5989] | 1096 | 2.199 | 0.8130 | Yes |
| 51 | NAB2 | NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627] | 1265 | 1.984 | 0.8171 | Yes |
| 52 | BCL2L11 | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | 1276 | 1.975 | 0.8255 | Yes |
| 53 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1297 | 1.962 | 0.8335 | Yes |
| 54 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 1334 | 1.916 | 0.8409 | Yes |
| 55 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1416 | 1.818 | 0.8467 | Yes |
| 56 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 1476 | 1.802 | 0.8530 | Yes |
| 57 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1874 | 1.520 | 0.8489 | Yes |
| 58 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 [Source:HGNC Symbol;Acc:HGNC:13744] | 1986 | 1.438 | 0.8522 | Yes |
| 59 | RAC2 | Rac family small GTPase 2 [Source:HGNC Symbol;Acc:HGNC:9802] | 2120 | 1.342 | 0.8544 | Yes |
| 60 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 2966 | 0.911 | 0.8356 | No |
| 61 | UBB | ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] | 3198 | 0.821 | 0.8329 | No |
| 62 | TSC22D1 | TSC22 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:16826] | 3834 | 0.587 | 0.8183 | No |
| 63 | BCL10 | BCL10 immune signaling adaptor [Source:HGNC Symbol;Acc:HGNC:989] | 4126 | 0.494 | 0.8126 | No |
| 64 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 4190 | 0.472 | 0.8130 | No |
| 65 | CCL23 | C-C motif chemokine ligand 23 [Source:HGNC Symbol;Acc:HGNC:10622] | 6216 | 0.000 | 0.7583 | No |
| 66 | TNFSF9 | TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] | 8738 | 0.000 | 0.6902 | No |
| 67 | LILRB4 | leukocyte immunoglobulin like receptor B4 [Source:HGNC Symbol;Acc:HGNC:6608] | 13333 | 0.000 | 0.5660 | No |
| 68 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19479 | 0.000 | 0.4000 | No |
| 69 | PLAUR | plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] | 22855 | 0.000 | 0.3088 | No |
| 70 | UBC | ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468] | 28434 | -0.076 | 0.1584 | No |
| 71 | CDC42EP4 | CDC42 effector protein 4 [Source:HGNC Symbol;Acc:HGNC:17147] | 28868 | -0.203 | 0.1476 | No |
| 72 | PHLDB1 | pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697] | 29123 | -0.266 | 0.1419 | No |
| 73 | RREB1 | ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449] | 30060 | -0.500 | 0.1188 | No |
| 74 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] | 31678 | -0.957 | 0.0793 | No |
| 75 | PKM | pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] | 32749 | -1.347 | 0.0563 | No |
| 76 | RHOB | ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668] | 33398 | -1.552 | 0.0455 | No |
| 77 | MT1X | metallothionein 1X [Source:HGNC Symbol;Acc:HGNC:7405] | 34213 | -1.936 | 0.0320 | No |
| 78 | BHLHE40 | basic helix-loop-helix family member e40 [Source:HGNC Symbol;Acc:HGNC:1046] | 35837 | -3.017 | 0.0013 | No |
| 79 | TXNIP | thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952] | 35949 | -3.129 | 0.0120 | No |
| 80 | SCD | stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] | 36875 | -4.299 | 0.0058 | No |
