Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | HECKER_IFNB1_TARGETS |
| Enrichment Score (ES) | 0.880513 |
| Normalized Enrichment Score (NES) | 2.1807065 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 19 | 4.971 | 0.0296 | Yes |
| 2 | MX2 | MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] | 36 | 4.945 | 0.0592 | Yes |
| 3 | GBP1 | guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182] | 47 | 4.882 | 0.0885 | Yes |
| 4 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 51 | 4.875 | 0.1180 | Yes |
| 5 | MX1 | MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] | 54 | 4.870 | 0.1475 | Yes |
| 6 | CMPK2 | cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] | 59 | 4.856 | 0.1768 | Yes |
| 7 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 63 | 4.848 | 0.2061 | Yes |
| 8 | OASL | 2'-5'-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] | 73 | 4.798 | 0.2350 | Yes |
| 9 | IRF7 | interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] | 96 | 4.689 | 0.2628 | Yes |
| 10 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 102 | 4.637 | 0.2908 | Yes |
| 11 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 111 | 4.590 | 0.3184 | Yes |
| 12 | DHX58 | DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517] | 121 | 4.521 | 0.3456 | Yes |
| 13 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 [Source:HGNC Symbol;Acc:HGNC:26072] | 143 | 4.411 | 0.3718 | Yes |
| 14 | DDX60 | DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] | 182 | 4.222 | 0.3964 | Yes |
| 15 | IFI44 | interferon induced protein 44 [Source:HGNC Symbol;Acc:HGNC:16938] | 207 | 4.163 | 0.4209 | Yes |
| 16 | DDX58 | DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102] | 213 | 4.127 | 0.4458 | Yes |
| 17 | IFI35 | interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] | 217 | 4.103 | 0.4706 | Yes |
| 18 | SIGLEC1 | sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127] | 228 | 4.064 | 0.4950 | Yes |
| 19 | C3AR1 | complement C3a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1319] | 251 | 3.979 | 0.5185 | Yes |
| 20 | STAT1 | signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362] | 252 | 3.978 | 0.5427 | Yes |
| 21 | SAMD9 | sterile alpha motif domain containing 9 [Source:HGNC Symbol;Acc:HGNC:1348] | 287 | 3.852 | 0.5651 | Yes |
| 22 | PARP12 | poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919] | 290 | 3.839 | 0.5883 | Yes |
| 23 | OAS1 | 2'-5'-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] | 301 | 3.811 | 0.6112 | Yes |
| 24 | OAS2 | 2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] | 310 | 3.764 | 0.6338 | Yes |
| 25 | SAMD9L | sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349] | 320 | 3.719 | 0.6561 | Yes |
| 26 | LGALS3BP | galectin 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6564] | 326 | 3.698 | 0.6784 | Yes |
| 27 | EPSTI1 | epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] | 368 | 3.551 | 0.6988 | Yes |
| 28 | OAS3 | 2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] | 484 | 3.259 | 0.7155 | Yes |
| 29 | STAP1 | signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133] | 489 | 3.236 | 0.7350 | Yes |
| 30 | ISG15 | ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] | 497 | 3.222 | 0.7543 | Yes |
| 31 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 597 | 2.997 | 0.7698 | Yes |
| 32 | CLU | clusterin [Source:HGNC Symbol;Acc:HGNC:2095] | 606 | 2.983 | 0.7877 | Yes |
| 33 | PNPT1 | polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166] | 640 | 2.917 | 0.8045 | Yes |
| 34 | CYP4F3 | cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646] | 696 | 2.802 | 0.8200 | Yes |
| 35 | PARP9 | poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] | 752 | 2.696 | 0.8349 | Yes |
| 36 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437] | 877 | 2.551 | 0.8470 | Yes |
| 37 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 1008 | 2.327 | 0.8576 | Yes |
| 38 | PLSCR1 | phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092] | 1261 | 1.989 | 0.8628 | Yes |
| 39 | PDZK1IP1 | PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] | 1405 | 1.834 | 0.8701 | Yes |
| 40 | LAP3 | leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] | 1426 | 1.810 | 0.8805 | Yes |
| 41 | SH3BGRL2 | SH3 domain binding glutamate rich protein like 2 [Source:HGNC Symbol;Acc:HGNC:15567] | 2429 | 1.157 | 0.8604 | No |
| 42 | TMEM140 | transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] | 3329 | 0.771 | 0.8408 | No |
| 43 | ITGA2B | integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] | 3440 | 0.724 | 0.8422 | No |
| 44 | MYL9 | myosin light chain 9 [Source:HGNC Symbol;Acc:HGNC:15754] | 3583 | 0.677 | 0.8425 | No |
| 45 | IFI27 | interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] | 3718 | 0.628 | 0.8427 | No |
| 46 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 [Source:HGNC Symbol;Acc:HGNC:24368] | 4299 | 0.428 | 0.8296 | No |
| 47 | SCO2 | synthesis of cytochrome C oxidase 2 [Source:HGNC Symbol;Acc:HGNC:10604] | 5243 | 0.159 | 0.8051 | No |
| 48 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 5246 | 0.159 | 0.8060 | No |
| 49 | HES4 | hes family bHLH transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:24149] | 7037 | 0.000 | 0.7576 | No |
| 50 | ARG1 | arginase 1 [Source:HGNC Symbol;Acc:HGNC:663] | 7136 | 0.000 | 0.7550 | No |
| 51 | CD163 | CD163 molecule [Source:HGNC Symbol;Acc:HGNC:1631] | 7591 | 0.000 | 0.7427 | No |
| 52 | LY6E | lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727] | 9109 | 0.000 | 0.7017 | No |
| 53 | FCER1A | Fc fragment of IgE receptor Ia [Source:HGNC Symbol;Acc:HGNC:3609] | 9771 | 0.000 | 0.6838 | No |
| 54 | TYMP | thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148] | 10114 | 0.000 | 0.6746 | No |
| 55 | RTP4 | receptor transporter protein 4 [Source:HGNC Symbol;Acc:HGNC:23992] | 10411 | 0.000 | 0.6666 | No |
| 56 | GZMB | granzyme B [Source:HGNC Symbol;Acc:HGNC:4709] | 12137 | 0.000 | 0.6200 | No |
| 57 | APOBEC3A | apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] | 12356 | 0.000 | 0.6141 | No |
| 58 | APOBEC3B | apolipoprotein B mRNA editing enzyme catalytic subunit 3B [Source:HGNC Symbol;Acc:HGNC:17352] | 12359 | 0.000 | 0.6140 | No |
| 59 | TCL1A | T cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648] | 12965 | 0.000 | 0.5977 | No |
| 60 | TNFAIP6 | TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] | 15413 | 0.000 | 0.5315 | No |
| 61 | G0S2 | G0/G1 switch 2 [Source:HGNC Symbol;Acc:HGNC:30229] | 15714 | 0.000 | 0.5234 | No |
| 62 | GP9 | glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444] | 17063 | 0.000 | 0.4870 | No |
| 63 | SERPING1 | serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] | 17738 | 0.000 | 0.4688 | No |
| 64 | SPON2 | spondin 2 [Source:HGNC Symbol;Acc:HGNC:11253] | 18955 | 0.000 | 0.4359 | No |
| 65 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19468 | 0.000 | 0.4221 | No |
| 66 | CHI3L1 | chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] | 19877 | 0.000 | 0.4110 | No |
| 67 | IFIT5 | interferon induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:HGNC:13328] | 20260 | 0.000 | 0.4007 | No |
| 68 | IFI44L | interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] | 20701 | 0.000 | 0.3888 | No |
| 69 | KCNJ15 | potassium inwardly rectifying channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261] | 20921 | 0.000 | 0.3829 | No |
| 70 | KLRD1 | killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378] | 21004 | 0.000 | 0.3807 | No |
| 71 | LAMP3 | lysosomal associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:14582] | 21587 | 0.000 | 0.3650 | No |
| 72 | CABP5 | calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714] | 21849 | 0.000 | 0.3579 | No |
| 73 | ZBP1 | Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] | 23117 | 0.000 | 0.3237 | No |
| 74 | MS4A4A | membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371] | 23244 | 0.000 | 0.3203 | No |
| 75 | XAF1 | XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] | 24519 | 0.000 | 0.2858 | No |
| 76 | C1QB | complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242] | 24794 | 0.000 | 0.2784 | No |
| 77 | C1QA | complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241] | 24795 | 0.000 | 0.2784 | No |
| 78 | C1QC | complement C1q C chain [Source:HGNC Symbol;Acc:HGNC:1245] | 24813 | 0.000 | 0.2780 | No |
| 79 | FFAR2 | free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501] | 25387 | 0.000 | 0.2625 | No |
| 80 | IFI6 | interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] | 25400 | 0.000 | 0.2621 | No |
| 81 | MMP25 | matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246] | 25588 | 0.000 | 0.2571 | No |
| 82 | CMTM5 | CKLF like MARVEL transmembrane domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19176] | 26940 | 0.000 | 0.2206 | No |
| 83 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173] | 26954 | 0.000 | 0.2202 | No |
| 84 | TRBV27 | T cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208] | 27582 | 0.000 | 0.2033 | No |
| 85 | CCL8 | C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635] | 27830 | 0.000 | 0.1966 | No |
| 86 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27840 | 0.000 | 0.1964 | No |
| 87 | RPS23 | ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:10410] | 30432 | -0.589 | 0.1299 | No |
| 88 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 30643 | -0.644 | 0.1281 | No |
| 89 | TREML1 | triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434] | 31241 | -0.827 | 0.1170 | No |
| 90 | JUP | junction plakoglobin [Source:HGNC Symbol;Acc:HGNC:6207] | 33074 | -1.497 | 0.0766 | No |
| 91 | PROS1 | protein S [Source:HGNC Symbol;Acc:HGNC:9456] | 33687 | -1.684 | 0.0702 | No |
| 92 | MGAM | maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043] | 36387 | -3.579 | 0.0190 | No |
