Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ISHIDA_E2F_TARGETS |
| Enrichment Score (ES) | -0.8398323 |
| Normalized Enrichment Score (NES) | -1.6395602 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.012196918 |
| FWER p-Value | 0.152 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ANXA8L1 | annexin A8 like 1 [Source:HGNC Symbol;Acc:HGNC:23334] | 26990 | 0.000 | -0.7287 | No |
| 2 | PTTG1 | PTTG1 regulator of sister chromatid separation, securin [Source:HGNC Symbol;Acc:HGNC:9690] | 30207 | -0.543 | -0.8115 | No |
| 3 | CDT1 | chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576] | 30919 | -0.718 | -0.8253 | No |
| 4 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.8328 | Yes |
| 5 | DCTPP1 | dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777] | 31700 | -0.964 | -0.8326 | Yes |
| 6 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 31736 | -0.972 | -0.8263 | Yes |
| 7 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 31758 | -0.979 | -0.8196 | Yes |
| 8 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31894 | -1.023 | -0.8156 | Yes |
| 9 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.8143 | Yes |
| 10 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32455 | -1.235 | -0.8132 | Yes |
| 11 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.8097 | Yes |
| 12 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 32989 | -1.461 | -0.8069 | Yes |
| 13 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.8064 | Yes |
| 14 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 33929 | -1.793 | -0.8073 | Yes |
| 15 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 34381 | -2.017 | -0.8044 | Yes |
| 16 | CDK2 | cyclin dependent kinase 2 [Source:HGNC Symbol;Acc:HGNC:1771] | 34829 | -2.298 | -0.7993 | Yes |
| 17 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.7876 | Yes |
| 18 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35359 | -2.639 | -0.7761 | Yes |
| 19 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35484 | -2.727 | -0.7592 | Yes |
| 20 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.7401 | Yes |
| 21 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35559 | -2.806 | -0.7194 | Yes |
| 22 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35595 | -2.845 | -0.6991 | Yes |
| 23 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35620 | -2.871 | -0.6784 | Yes |
| 24 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.6570 | Yes |
| 25 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.6358 | Yes |
| 26 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35644 | -2.897 | -0.6144 | Yes |
| 27 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 35783 | -2.979 | -0.5959 | Yes |
| 28 | LBR | lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518] | 35799 | -2.990 | -0.5741 | Yes |
| 29 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.5520 | Yes |
| 30 | RPA1 | replication protein A1 [Source:HGNC Symbol;Acc:HGNC:10289] | 35922 | -3.092 | -0.5320 | Yes |
| 31 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35936 | -3.111 | -0.5091 | Yes |
| 32 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35937 | -3.113 | -0.4859 | Yes |
| 33 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36045 | -3.244 | -0.4647 | Yes |
| 34 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.4417 | Yes |
| 35 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36135 | -3.335 | -0.4177 | Yes |
| 36 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36147 | -3.344 | -0.3931 | Yes |
| 37 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.3704 | Yes |
| 38 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36321 | -3.512 | -0.3457 | Yes |
| 39 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36332 | -3.523 | -0.3197 | Yes |
| 40 | ANLN | anillin actin binding protein [Source:HGNC Symbol;Acc:HGNC:14082] | 36337 | -3.529 | -0.2935 | Yes |
| 41 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.2673 | Yes |
| 42 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36385 | -3.578 | -0.2417 | Yes |
| 43 | SGO1 | shugoshin 1 [Source:HGNC Symbol;Acc:HGNC:25088] | 36429 | -3.624 | -0.2159 | Yes |
| 44 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.1902 | Yes |
| 45 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36527 | -3.755 | -0.1629 | Yes |
| 46 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.1358 | Yes |
| 47 | RB1 | RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884] | 36596 | -3.855 | -0.1075 | Yes |
| 48 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.0788 | Yes |
| 49 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36610 | -3.875 | -0.0502 | Yes |
| 50 | DUT | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:HGNC:3078] | 36711 | -3.993 | -0.0231 | Yes |
| 51 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 36948 | -4.472 | 0.0038 | Yes |
