Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | KANG_DOXORUBICIN_RESISTANCE_UP |
| Enrichment Score (ES) | -0.81004775 |
| Normalized Enrichment Score (NES) | -1.6066492 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.024917435 |
| FWER p-Value | 0.436 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797] | 679 | 2.838 | 0.0034 | No |
| 2 | ABCC1 | ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51] | 1974 | 1.451 | -0.0205 | No |
| 3 | NPIPA1 | nuclear pore complex interacting protein family member A1 [Source:HGNC Symbol;Acc:HGNC:7909] | 2450 | 1.146 | -0.0245 | No |
| 4 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 5609 | 0.153 | -0.1086 | No |
| 5 | NQO1 | NAD(P)H quinone dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:2874] | 5654 | 0.151 | -0.1086 | No |
| 6 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.5867 | No |
| 7 | POLA2 | DNA polymerase alpha 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:30073] | 29922 | -0.461 | -0.7603 | No |
| 8 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7616 | No |
| 9 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 31304 | -0.852 | -0.7871 | No |
| 10 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 31758 | -0.979 | -0.7918 | No |
| 11 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.7940 | No |
| 12 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 32379 | -1.207 | -0.7908 | No |
| 13 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33093 | -1.504 | -0.7985 | Yes |
| 14 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 33128 | -1.519 | -0.7878 | Yes |
| 15 | POLQ | DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186] | 33738 | -1.705 | -0.7912 | Yes |
| 16 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.7853 | Yes |
| 17 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.7743 | Yes |
| 18 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34248 | -1.957 | -0.7611 | Yes |
| 19 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 34280 | -1.977 | -0.7468 | Yes |
| 20 | NEMP1 | nuclear envelope integral membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29001] | 34478 | -2.078 | -0.7362 | Yes |
| 21 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.7235 | Yes |
| 22 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.7108 | Yes |
| 23 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 34811 | -2.286 | -0.6937 | Yes |
| 24 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34864 | -2.323 | -0.6774 | Yes |
| 25 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34947 | -2.382 | -0.6613 | Yes |
| 26 | DTYMK | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | 34952 | -2.382 | -0.6432 | Yes |
| 27 | BARD1 | BRCA1 associated RING domain 1 [Source:HGNC Symbol;Acc:HGNC:952] | 35061 | -2.395 | -0.6278 | Yes |
| 28 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35122 | -2.440 | -0.6108 | Yes |
| 29 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35187 | -2.501 | -0.5934 | Yes |
| 30 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.5748 | Yes |
| 31 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 35282 | -2.576 | -0.5568 | Yes |
| 32 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35504 | -2.750 | -0.5417 | Yes |
| 33 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.5216 | Yes |
| 34 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.5017 | Yes |
| 35 | ATAD2 | ATPase family AAA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30123] | 35776 | -2.971 | -0.4828 | Yes |
| 36 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35792 | -2.983 | -0.4604 | Yes |
| 37 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.4379 | Yes |
| 38 | OIP5 | Opa interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:20300] | 35911 | -3.088 | -0.4170 | Yes |
| 39 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35936 | -3.111 | -0.3938 | Yes |
| 40 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35969 | -3.152 | -0.3706 | Yes |
| 41 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36020 | -3.209 | -0.3474 | Yes |
| 42 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36087 | -3.264 | -0.3242 | Yes |
| 43 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36205 | -3.402 | -0.3013 | Yes |
| 44 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36250 | -3.453 | -0.2761 | Yes |
| 45 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.2500 | Yes |
| 46 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.2243 | Yes |
| 47 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36332 | -3.523 | -0.1979 | Yes |
| 48 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.1712 | Yes |
| 49 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.1471 | Yes |
| 50 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.1188 | Yes |
| 51 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.0919 | Yes |
| 52 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 36948 | -4.472 | -0.0670 | Yes |
| 53 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | -0.0329 | Yes |
| 54 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 37036 | -4.755 | 0.0015 | Yes |
