Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | KONG_E2F3_TARGETS |
| Enrichment Score (ES) | -0.7916578 |
| Normalized Enrichment Score (NES) | -1.6592311 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.007362675 |
| FWER p-Value | 0.069 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IGF2BP1 | insulin like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28866] | 482 | 3.268 | 0.0025 | No |
| 2 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 999 | 2.337 | -0.0004 | No |
| 3 | GAS5 | growth arrest specific 5 [Source:HGNC Symbol;Acc:HGNC:16355] | 1001 | 2.335 | 0.0107 | No |
| 4 | NR1D1 | nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962] | 2113 | 1.355 | -0.0129 | No |
| 5 | SRSF7 | serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789] | 2829 | 0.977 | -0.0276 | No |
| 6 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 2897 | 0.945 | -0.0250 | No |
| 7 | MED1 | mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234] | 4170 | 0.480 | -0.0571 | No |
| 8 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 5609 | 0.153 | -0.0952 | No |
| 9 | H4C15 | H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607] | 12541 | 0.000 | -0.2826 | No |
| 10 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16647 | 0.000 | -0.3935 | No |
| 11 | MYB | MYB proto-oncogene, transcription factor [Source:HGNC Symbol;Acc:HGNC:7545] | 19183 | 0.000 | -0.4621 | No |
| 12 | TAL2 | TAL bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11557] | 19232 | 0.000 | -0.4634 | No |
| 13 | GP1BA | glycoprotein Ib platelet subunit alpha [Source:HGNC Symbol;Acc:HGNC:4439] | 20305 | 0.000 | -0.4923 | No |
| 14 | PRL | prolactin [Source:HGNC Symbol;Acc:HGNC:9445] | 24783 | 0.000 | -0.6134 | No |
| 15 | PSORS1C2 | psoriasis susceptibility 1 candidate 2 [Source:HGNC Symbol;Acc:HGNC:17199] | 25463 | 0.000 | -0.6317 | No |
| 16 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 27728 | 0.000 | -0.6929 | No |
| 17 | NUP50 | nucleoporin 50 [Source:HGNC Symbol;Acc:HGNC:8065] | 28996 | -0.232 | -0.7261 | No |
| 18 | RPL12 | ribosomal protein L12 [Source:HGNC Symbol;Acc:HGNC:10302] | 29492 | -0.361 | -0.7377 | No |
| 19 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7522 | No |
| 20 | MAPK8 | mitogen-activated protein kinase 8 [Source:HGNC Symbol;Acc:HGNC:6881] | 30160 | -0.529 | -0.7508 | No |
| 21 | FBXO45 | F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148] | 30502 | -0.607 | -0.7571 | No |
| 22 | CDC7 | cell division cycle 7 [Source:HGNC Symbol;Acc:HGNC:1745] | 30627 | -0.640 | -0.7574 | No |
| 23 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 30754 | -0.673 | -0.7576 | No |
| 24 | CBX2 | chromobox 2 [Source:HGNC Symbol;Acc:HGNC:1552] | 31584 | -0.921 | -0.7757 | No |
| 25 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 31758 | -0.979 | -0.7757 | No |
| 26 | TAF1D | TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759] | 32205 | -1.130 | -0.7824 | No |
| 27 | SKP2 | S-phase kinase associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10901] | 32548 | -1.271 | -0.7856 | Yes |
| 28 | FAM111A | family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725] | 32626 | -1.298 | -0.7816 | Yes |
| 29 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.7770 | Yes |
| 30 | RPRD1B | regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209] | 32803 | -1.370 | -0.7735 | Yes |
| 31 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 32989 | -1.461 | -0.7716 | Yes |
| 32 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33093 | -1.504 | -0.7672 | Yes |
| 33 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 33128 | -1.519 | -0.7609 | Yes |
| 34 | HLX | H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978] | 33129 | -1.520 | -0.7537 | Yes |
| 35 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.7537 | Yes |
| 36 | RPL3 | ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332] | 33581 | -1.638 | -0.7508 | Yes |
| 37 | RBBP8 | RB binding protein 8, endonuclease [Source:HGNC Symbol;Acc:HGNC:9891] | 33676 | -1.679 | -0.7453 | Yes |
| 38 | TACC3 | transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524] | 33842 | -1.752 | -0.7415 | Yes |
| 39 | INCENP | inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058] | 33944 | -1.801 | -0.7357 | Yes |
| 40 | RBL1 | RB transcriptional corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:9893] | 33963 | -1.808 | -0.7276 | Yes |
| 41 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.7243 | Yes |
| 42 | CENPH | centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268] | 34317 | -2.002 | -0.7185 | Yes |
| 43 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 34381 | -2.017 | -0.7106 | Yes |
| 44 | USP1 | ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607] | 34506 | -2.095 | -0.7040 | Yes |
| 45 | CENPQ | centromere protein Q [Source:HGNC Symbol;Acc:HGNC:21347] | 34544 | -2.117 | -0.6950 | Yes |
| 46 | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase [Source:HGNC Symbol;Acc:HGNC:20794] | 34590 | -2.144 | -0.6861 | Yes |
| 47 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.6765 | Yes |
| 48 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34638 | -2.171 | -0.6668 | Yes |
| 49 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 34811 | -2.286 | -0.6606 | Yes |
| 50 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.6523 | Yes |
| 51 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.6445 | Yes |
| 52 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 35171 | -2.487 | -0.6359 | Yes |
| 53 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35189 | -2.503 | -0.6245 | Yes |
| 54 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.6132 | Yes |
| 55 | NCAPG2 | non-SMC condensin II complex subunit G2 [Source:HGNC Symbol;Acc:HGNC:21904] | 35282 | -2.576 | -0.6027 | Yes |
| 56 | SPDL1 | spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010] | 35339 | -2.617 | -0.5918 | Yes |
| 57 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35359 | -2.639 | -0.5798 | Yes |
| 58 | CENPK | centromere protein K [Source:HGNC Symbol;Acc:HGNC:29479] | 35457 | -2.706 | -0.5696 | Yes |
| 59 | CDC6 | cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744] | 35504 | -2.750 | -0.5578 | Yes |
| 60 | SYCE2 | synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411] | 35509 | -2.752 | -0.5448 | Yes |
| 61 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 35517 | -2.758 | -0.5319 | Yes |
| 62 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35559 | -2.806 | -0.5197 | Yes |
| 63 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 35611 | -2.858 | -0.5076 | Yes |
| 64 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35620 | -2.871 | -0.4942 | Yes |
| 65 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.4808 | Yes |
| 66 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35644 | -2.897 | -0.4673 | Yes |
| 67 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35697 | -2.900 | -0.4550 | Yes |
| 68 | FIGNL1 | fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286] | 35699 | -2.901 | -0.4412 | Yes |
| 69 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35789 | -2.981 | -0.4295 | Yes |
| 70 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 35805 | -2.996 | -0.4157 | Yes |
| 71 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.4015 | Yes |
| 72 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35936 | -3.111 | -0.3902 | Yes |
| 73 | DNA2 | DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939] | 35937 | -3.113 | -0.3754 | Yes |
| 74 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35969 | -3.152 | -0.3613 | Yes |
| 75 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36011 | -3.197 | -0.3473 | Yes |
| 76 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36017 | -3.205 | -0.3322 | Yes |
| 77 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36020 | -3.209 | -0.3170 | Yes |
| 78 | CCNE1 | cyclin E1 [Source:HGNC Symbol;Acc:HGNC:1589] | 36045 | -3.244 | -0.3023 | Yes |
| 79 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36132 | -3.332 | -0.2888 | Yes |
| 80 | CCNF | cyclin F [Source:HGNC Symbol;Acc:HGNC:1591] | 36199 | -3.393 | -0.2745 | Yes |
| 81 | PBK | PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282] | 36205 | -3.402 | -0.2585 | Yes |
| 82 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.2425 | Yes |
| 83 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 36221 | -3.418 | -0.2265 | Yes |
| 84 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36263 | -3.468 | -0.2111 | Yes |
| 85 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.1948 | Yes |
| 86 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.1792 | Yes |
| 87 | PSIP1 | PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527] | 36312 | -3.503 | -0.1627 | Yes |
| 88 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36332 | -3.523 | -0.1465 | Yes |
| 89 | BRCA1 | BRCA1 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1100] | 36365 | -3.555 | -0.1305 | Yes |
| 90 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.1166 | Yes |
| 91 | DEPDC1 | DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949] | 36512 | -3.711 | -0.0993 | Yes |
| 92 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36567 | -3.812 | -0.0826 | Yes |
| 93 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.0648 | Yes |
| 94 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.0470 | Yes |
| 95 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36610 | -3.875 | -0.0288 | Yes |
| 96 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36884 | -4.334 | -0.0157 | Yes |
| 97 | TK1 | thymidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:11830] | 36948 | -4.472 | 0.0038 | Yes |
