Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | MORI_IMMATURE_B_LYMPHOCYTE_DN |
| Enrichment Score (ES) | -0.7822783 |
| Normalized Enrichment Score (NES) | -1.6363131 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011162622 |
| FWER p-Value | 0.174 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | H2AC4 | H2A clustered histone 4 [Source:HGNC Symbol;Acc:HGNC:4734] | 999 | 2.337 | -0.0145 | No |
| 2 | TXN | thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435] | 1756 | 1.602 | -0.0263 | No |
| 3 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 1970 | 1.456 | -0.0243 | No |
| 4 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] | 2665 | 1.053 | -0.0374 | No |
| 5 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3337 | 0.767 | -0.0514 | No |
| 6 | HMGN2 | high mobility group nucleosomal binding domain 2 [Source:HGNC Symbol;Acc:HGNC:4986] | 3671 | 0.644 | -0.0569 | No |
| 7 | PREP | prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358] | 4566 | 0.348 | -0.0792 | No |
| 8 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 5609 | 0.153 | -0.1066 | No |
| 9 | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [Source:HGNC Symbol;Acc:HGNC:11101] | 5878 | 0.081 | -0.1134 | No |
| 10 | RAG1 | recombination activating 1 [Source:HGNC Symbol;Acc:HGNC:9831] | 12408 | 0.000 | -0.2898 | No |
| 11 | CDCA5 | cell division cycle associated 5 [Source:HGNC Symbol;Acc:HGNC:14626] | 16647 | 0.000 | -0.4044 | No |
| 12 | IGLL1 | immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870] | 18427 | 0.000 | -0.4525 | No |
| 13 | ENPEP | glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355] | 24348 | 0.000 | -0.6125 | No |
| 14 | RAMP1 | receptor activity modifying protein 1 [Source:HGNC Symbol;Acc:HGNC:9843] | 25024 | 0.000 | -0.6307 | No |
| 15 | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [Source:HGNC Symbol;Acc:HGNC:11100] | 28363 | -0.054 | -0.7206 | No |
| 16 | ACTN4 | actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166] | 29596 | -0.387 | -0.7519 | No |
| 17 | PRDX4 | peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169] | 30103 | -0.511 | -0.7628 | No |
| 18 | ANP32E | acidic nuclear phosphoprotein 32 family member E [Source:HGNC Symbol;Acc:HGNC:16673] | 30578 | -0.627 | -0.7722 | No |
| 19 | CBX1 | chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551] | 30747 | -0.672 | -0.7732 | No |
| 20 | DCK | deoxycytidine kinase [Source:HGNC Symbol;Acc:HGNC:2704] | 30754 | -0.673 | -0.7697 | No |
| 21 | PCK2 | phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] | 31084 | -0.779 | -0.7745 | No |
| 22 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31243 | -0.829 | -0.7743 | No |
| 23 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.7749 | No |
| 24 | HAUS3 | HAUS augmin like complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:28719] | 31714 | -0.965 | -0.7771 | Yes |
| 25 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 31758 | -0.979 | -0.7730 | Yes |
| 26 | HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:HGNC:24941] | 31787 | -0.987 | -0.7685 | Yes |
| 27 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31894 | -1.023 | -0.7659 | Yes |
| 28 | TUBB4B | tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] | 31976 | -1.055 | -0.7624 | Yes |
| 29 | CDC45 | cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] | 32023 | -1.073 | -0.7579 | Yes |
| 30 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.7554 | Yes |
| 31 | UCK2 | uridine-cytidine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12562] | 32159 | -1.115 | -0.7496 | Yes |
| 32 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 32379 | -1.207 | -0.7490 | Yes |
| 33 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32455 | -1.235 | -0.7444 | Yes |
| 34 | RAD51 | RAD51 recombinase [Source:HGNC Symbol;Acc:HGNC:9817] | 32989 | -1.461 | -0.7510 | Yes |
| 35 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33093 | -1.504 | -0.7457 | Yes |
| 36 | SLC16A1 | solute carrier family 16 member 1 [Source:HGNC Symbol;Acc:HGNC:10922] | 33095 | -1.505 | -0.7377 | Yes |
| 37 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.7376 | Yes |
| 38 | RBBP4 | RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887] | 33409 | -1.558 | -0.7294 | Yes |
| 39 | LGALS1 | galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561] | 33426 | -1.566 | -0.7214 | Yes |
| 40 | HMGB1 | high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983] | 33729 | -1.701 | -0.7205 | Yes |
| 41 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 33775 | -1.722 | -0.7125 | Yes |
| 42 | CKAP5 | cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] | 33962 | -1.808 | -0.7078 | Yes |
| 43 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 33975 | -1.818 | -0.6984 | Yes |
| 44 | TUBA1B | tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809] | 34328 | -2.007 | -0.6971 | Yes |
| 45 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 34381 | -2.017 | -0.6877 | Yes |
| 46 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 34433 | -2.054 | -0.6781 | Yes |
| 47 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 34451 | -2.062 | -0.6675 | Yes |
| 48 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.6651 | Yes |
| 49 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.6552 | Yes |
| 50 | TUBB | tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778] | 34939 | -2.379 | -0.6429 | Yes |
| 51 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.6331 | Yes |
| 52 | CDKN3 | cyclin dependent kinase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:1791] | 35122 | -2.440 | -0.6218 | Yes |
| 53 | CHEK1 | checkpoint kinase 1 [Source:HGNC Symbol;Acc:HGNC:1925] | 35152 | -2.473 | -0.6094 | Yes |
| 54 | XRCC6 | X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055] | 35153 | -2.475 | -0.5961 | Yes |
| 55 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35189 | -2.503 | -0.5836 | Yes |
| 56 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35359 | -2.639 | -0.5740 | Yes |
| 57 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35524 | -2.765 | -0.5636 | Yes |
| 58 | KIFC1 | kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389] | 35525 | -2.767 | -0.5488 | Yes |
| 59 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.5345 | Yes |
| 60 | NCAPH | non-SMC condensin I complex subunit H [Source:HGNC Symbol;Acc:HGNC:1112] | 35559 | -2.806 | -0.5196 | Yes |
| 61 | STMN1 | stathmin 1 [Source:HGNC Symbol;Acc:HGNC:6510] | 35595 | -2.845 | -0.5053 | Yes |
| 62 | IQGAP3 | IQ motif containing GTPase activating protein 3 [Source:HGNC Symbol;Acc:HGNC:20669] | 35611 | -2.858 | -0.4904 | Yes |
| 63 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35620 | -2.871 | -0.4752 | Yes |
| 64 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.4599 | Yes |
| 65 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.4446 | Yes |
| 66 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35697 | -2.900 | -0.4307 | Yes |
| 67 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 35783 | -2.979 | -0.4171 | Yes |
| 68 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 35805 | -2.996 | -0.4016 | Yes |
| 69 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.3856 | Yes |
| 70 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35818 | -3.002 | -0.3697 | Yes |
| 71 | GSN | gelsolin [Source:HGNC Symbol;Acc:HGNC:4620] | 35909 | -3.083 | -0.3556 | Yes |
| 72 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 35985 | -3.169 | -0.3406 | Yes |
| 73 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36017 | -3.205 | -0.3243 | Yes |
| 74 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.3089 | Yes |
| 75 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) [Source:HGNC Symbol;Acc:HGNC:11003] | 36122 | -3.318 | -0.2916 | Yes |
| 76 | CDCA7 | cell division cycle associated 7 [Source:HGNC Symbol;Acc:HGNC:14628] | 36147 | -3.344 | -0.2743 | Yes |
| 77 | DNMT1 | DNA methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976] | 36216 | -3.414 | -0.2579 | Yes |
| 78 | PTGR1 | prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429] | 36226 | -3.421 | -0.2398 | Yes |
| 79 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.2222 | Yes |
| 80 | HMGB3 | high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004] | 36321 | -3.512 | -0.2048 | Yes |
| 81 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.1864 | Yes |
| 82 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36385 | -3.578 | -0.1683 | Yes |
| 83 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.1516 | Yes |
| 84 | CDKN2C | cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789] | 36527 | -3.755 | -0.1321 | Yes |
| 85 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36567 | -3.812 | -0.1127 | Yes |
| 86 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.0925 | Yes |
| 87 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36597 | -3.856 | -0.0723 | Yes |
| 88 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.0517 | Yes |
| 89 | H2AZ2 | H2A.Z variant histone 2 [Source:HGNC Symbol;Acc:HGNC:20664] | 36717 | -4.001 | -0.0333 | Yes |
| 90 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36726 | -4.014 | -0.0120 | Yes |
| 91 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36761 | -4.065 | 0.0089 | Yes |
