Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | REACTOME_INTERLEUKIN_10_SIGNALING |
| Enrichment Score (ES) | 0.8842114 |
| Normalized Enrichment Score (NES) | 1.9816906 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.9140172E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 5 | 4.992 | 0.0519 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 10 | 4.988 | 0.1037 | Yes |
| 3 | IL1A | interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] | 11 | 4.984 | 0.1556 | Yes |
| 4 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 15 | 4.981 | 0.2074 | Yes |
| 5 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 16 | 4.973 | 0.2592 | Yes |
| 6 | PTGS2 | prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605] | 32 | 4.953 | 0.3104 | Yes |
| 7 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 37 | 4.938 | 0.3617 | Yes |
| 8 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 42 | 4.905 | 0.4127 | Yes |
| 9 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 45 | 4.889 | 0.4635 | Yes |
| 10 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 85 | 4.742 | 0.5119 | Yes |
| 11 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 102 | 4.637 | 0.5597 | Yes |
| 12 | IL10 | interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5962] | 115 | 4.566 | 0.6070 | Yes |
| 13 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 116 | 4.554 | 0.6544 | Yes |
| 14 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 142 | 4.425 | 0.6998 | Yes |
| 15 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 150 | 4.382 | 0.7453 | Yes |
| 16 | PTAFR | platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582] | 236 | 4.050 | 0.7852 | Yes |
| 17 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 351 | 3.623 | 0.8198 | Yes |
| 18 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 596 | 3.001 | 0.8445 | Yes |
| 19 | STAT3 | signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364] | 1184 | 2.092 | 0.8504 | Yes |
| 20 | TNFRSF1A | TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916] | 1237 | 2.020 | 0.8701 | Yes |
| 21 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1416 | 1.818 | 0.8842 | Yes |
| 22 | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606] | 2048 | 1.393 | 0.8817 | No |
| 23 | FPR1 | formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826] | 2415 | 1.168 | 0.8840 | No |
| 24 | TYK2 | tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:12440] | 2884 | 0.952 | 0.8813 | No |
| 25 | CCR1 | C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602] | 4738 | 0.303 | 0.8344 | No |
| 26 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 4749 | 0.300 | 0.8373 | No |
| 27 | CCL19 | C-C motif chemokine ligand 19 [Source:HGNC Symbol;Acc:HGNC:10617] | 6206 | 0.000 | 0.7980 | No |
| 28 | CCL22 | C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] | 6217 | 0.000 | 0.7977 | No |
| 29 | CCL20 | C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] | 6220 | 0.000 | 0.7976 | No |
| 30 | IL18 | interleukin 18 [Source:HGNC Symbol;Acc:HGNC:5986] | 13687 | 0.000 | 0.5961 | No |
| 31 | CCL3L1 | C-C motif chemokine ligand 3 like 1 [Source:HGNC Symbol;Acc:HGNC:10628] | 14678 | 0.000 | 0.5694 | No |
| 32 | CCL3L3 | C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554] | 14680 | 0.000 | 0.5693 | No |
| 33 | IL1R1 | interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993] | 15797 | 0.000 | 0.5392 | No |
| 34 | IL1R2 | interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] | 15798 | 0.000 | 0.5392 | No |
| 35 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18237 | 0.000 | 0.4734 | No |
| 36 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19468 | 0.000 | 0.4402 | No |
| 37 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19477 | 0.000 | 0.4400 | No |
| 38 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19480 | 0.000 | 0.4399 | No |
| 39 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 21576 | 0.000 | 0.3834 | No |
| 40 | FCER2 | Fc fragment of IgE receptor II [Source:HGNC Symbol;Acc:HGNC:3612] | 23250 | 0.000 | 0.3382 | No |
| 41 | IL12A | interleukin 12A [Source:HGNC Symbol;Acc:HGNC:5969] | 24212 | 0.000 | 0.3123 | No |
| 42 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27840 | 0.000 | 0.2144 | No |
| 43 | CD80 | CD80 molecule [Source:HGNC Symbol;Acc:HGNC:1700] | 28020 | 0.000 | 0.2095 | No |
| 44 | JAK1 | Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190] | 28545 | -0.108 | 0.1965 | No |
| 45 | IL10RA | interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964] | 32105 | -1.105 | 0.1119 | No |
| 46 | IL10RB | interleukin 10 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:5965] | 34631 | -2.169 | 0.0664 | No |
