Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | SEKI_INFLAMMATORY_RESPONSE_LPS_UP |
| Enrichment Score (ES) | 0.82916945 |
| Normalized Enrichment Score (NES) | 1.9915059 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.302553E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LIF | LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] | 15 | 4.981 | 0.0284 | Yes |
| 2 | RSAD2 | radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] | 19 | 4.971 | 0.0570 | Yes |
| 3 | GBP4 | guanylate binding protein 4 [Source:HGNC Symbol;Acc:HGNC:20480] | 34 | 4.950 | 0.0853 | Yes |
| 4 | GBP6 | guanylate binding protein family member 6 [Source:HGNC Symbol;Acc:HGNC:25395] | 44 | 4.892 | 0.1133 | Yes |
| 5 | NFKBIZ | NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805] | 72 | 4.799 | 0.1403 | Yes |
| 6 | FOSL1 | FOS like 1, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:13718] | 76 | 4.788 | 0.1679 | Yes |
| 7 | CD40 | CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] | 79 | 4.762 | 0.1954 | Yes |
| 8 | SLC15A3 | solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068] | 90 | 4.724 | 0.2224 | Yes |
| 9 | CXCL10 | C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] | 102 | 4.637 | 0.2489 | Yes |
| 10 | GBP2 | guanylate binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4183] | 105 | 4.608 | 0.2755 | Yes |
| 11 | GADD45B | growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096] | 113 | 4.584 | 0.3018 | Yes |
| 12 | CSF1 | colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432] | 150 | 4.382 | 0.3262 | Yes |
| 13 | RND1 | Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314] | 180 | 4.230 | 0.3498 | Yes |
| 14 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 183 | 4.220 | 0.3742 | Yes |
| 15 | ZC3H12A | zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:HGNC:26259] | 218 | 4.103 | 0.3970 | Yes |
| 16 | EXOC3L4 | exocyst complex component 3 like 4 [Source:HGNC Symbol;Acc:HGNC:20120] | 231 | 4.054 | 0.4201 | Yes |
| 17 | ZMYND15 | zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] | 248 | 4.007 | 0.4428 | Yes |
| 18 | IER3 | immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392] | 266 | 3.940 | 0.4651 | Yes |
| 19 | TNFAIP3 | TNF alpha induced protein 3 [Source:HGNC Symbol;Acc:HGNC:11896] | 271 | 3.923 | 0.4877 | Yes |
| 20 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 307 | 3.782 | 0.5086 | Yes |
| 21 | GCH1 | GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193] | 321 | 3.713 | 0.5297 | Yes |
| 22 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 330 | 3.672 | 0.5507 | Yes |
| 23 | RAB20 | RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260] | 367 | 3.552 | 0.5703 | Yes |
| 24 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 383 | 3.515 | 0.5902 | Yes |
| 25 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 444 | 3.352 | 0.6080 | Yes |
| 26 | SOD2 | superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180] | 460 | 3.318 | 0.6267 | Yes |
| 27 | STX11 | syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429] | 495 | 3.227 | 0.6445 | Yes |
| 28 | SLC4A7 | solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033] | 503 | 3.202 | 0.6628 | Yes |
| 29 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 571 | 3.068 | 0.6787 | Yes |
| 30 | SLC11A2 | solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908] | 652 | 2.890 | 0.6932 | Yes |
| 31 | FAS | Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920] | 707 | 2.773 | 0.7078 | Yes |
| 32 | MAFF | MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] | 721 | 2.746 | 0.7233 | Yes |
| 33 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 763 | 2.669 | 0.7377 | Yes |
| 34 | RIPK2 | receptor interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:10020] | 778 | 2.636 | 0.7525 | Yes |
| 35 | SERPINA3 | serpin family A member 3 [Source:HGNC Symbol;Acc:HGNC:16] | 867 | 2.565 | 0.7650 | Yes |
| 36 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 890 | 2.532 | 0.7790 | Yes |
| 37 | SH3PXD2B | SH3 and PX domains 2B [Source:HGNC Symbol;Acc:HGNC:29242] | 995 | 2.341 | 0.7897 | Yes |
| 38 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 1229 | 2.026 | 0.7951 | Yes |
| 39 | BTG1 | BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130] | 1306 | 1.947 | 0.8043 | Yes |
| 40 | TLR2 | toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848] | 1313 | 1.940 | 0.8154 | Yes |
| 41 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1416 | 1.818 | 0.8232 | Yes |
| 42 | PTPRE | protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] | 1874 | 1.520 | 0.8196 | Yes |
| 43 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 1882 | 1.514 | 0.8282 | Yes |
| 44 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 2131 | 1.335 | 0.8292 | Yes |
| 45 | NEURL3 | neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] | 3211 | 0.818 | 0.8047 | No |
| 46 | GSAP | gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042] | 3463 | 0.715 | 0.8021 | No |
| 47 | EGR1 | early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] | 5246 | 0.159 | 0.7549 | No |
| 48 | SELE | selectin E [Source:HGNC Symbol;Acc:HGNC:10718] | 6993 | 0.000 | 0.7077 | No |
| 49 | PRRX1 | paired related homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9142] | 8486 | 0.000 | 0.6674 | No |
| 50 | CCRL2 | C-C motif chemokine receptor like 2 [Source:HGNC Symbol;Acc:HGNC:1612] | 8624 | 0.000 | 0.6637 | No |
| 51 | NGFR | nerve growth factor receptor [Source:HGNC Symbol;Acc:HGNC:7809] | 10226 | 0.000 | 0.6204 | No |
| 52 | ICOSLG | inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087] | 11123 | 0.000 | 0.5962 | No |
| 53 | EREG | epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] | 11439 | 0.000 | 0.5877 | No |
| 54 | VCAM1 | vascular cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:12663] | 13781 | 0.000 | 0.5245 | No |
| 55 | LRATD1 | LRAT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20743] | 18007 | 0.000 | 0.4103 | No |
| 56 | ICAM1 | intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344] | 18237 | 0.000 | 0.4041 | No |
| 57 | CXCL16 | C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] | 18881 | 0.000 | 0.3868 | No |
| 58 | OSMR | oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507] | 19007 | 0.000 | 0.3834 | No |
| 59 | CXCL6 | C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] | 19463 | 0.000 | 0.3711 | No |
| 60 | CXCL1 | C-X-C motif chemokine ligand 1 [Source:HGNC Symbol;Acc:HGNC:4602] | 19477 | 0.000 | 0.3707 | No |
| 61 | CXCL3 | C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] | 19479 | 0.000 | 0.3707 | No |
| 62 | TCIM | transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] | 19888 | 0.000 | 0.3597 | No |
| 63 | CASP4 | caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505] | 24018 | 0.000 | 0.2481 | No |
| 64 | ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif 7 [Source:HGNC Symbol;Acc:HGNC:223] | 24712 | 0.000 | 0.2294 | No |
| 65 | TSLP | thymic stromal lymphopoietin [Source:HGNC Symbol;Acc:HGNC:30743] | 26982 | 0.000 | 0.1681 | No |
| 66 | EGFR | epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236] | 27021 | 0.000 | 0.1671 | No |
| 67 | CCL7 | C-C motif chemokine ligand 7 [Source:HGNC Symbol;Acc:HGNC:10634] | 27832 | 0.000 | 0.1452 | No |
| 68 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27840 | 0.000 | 0.1450 | No |
| 69 | EGR2 | early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] | 30643 | -0.644 | 0.0730 | No |
| 70 | BIRC2 | baculoviral IAP repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:590] | 31860 | -1.010 | 0.0460 | No |
| 71 | TJP2 | tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828] | 32867 | -1.410 | 0.0270 | No |
| 72 | ABCB1 | ATP binding cassette subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:40] | 33066 | -1.494 | 0.0303 | No |
| 73 | BMP2 | bone morphogenetic protein 2 [Source:HGNC Symbol;Acc:HGNC:1069] | 33167 | -1.529 | 0.0364 | No |
| 74 | RFX5 | regulatory factor X5 [Source:HGNC Symbol;Acc:HGNC:9986] | 33414 | -1.562 | 0.0388 | No |
| 75 | EGR3 | early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240] | 33612 | -1.651 | 0.0430 | No |
| 76 | GPR68 | G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519] | 34642 | -2.175 | 0.0278 | No |
| 77 | SLCO4A1 | solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] | 35179 | -2.495 | 0.0277 | No |
| 78 | SCHIP1 | schwannomin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:15678] | 36810 | -4.135 | 0.0076 | No |
