Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | WP_LUNG_FIBROSIS |
| Enrichment Score (ES) | 0.8298682 |
| Normalized Enrichment Score (NES) | 1.9747021 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.7521275E-4 |
| FWER p-Value | 0.003 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 5 | 4.992 | 0.0518 | Yes |
| 2 | CSF3 | colony stimulating factor 3 [Source:HGNC Symbol;Acc:HGNC:2438] | 10 | 4.988 | 0.1036 | Yes |
| 3 | IL1B | interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] | 16 | 4.973 | 0.1553 | Yes |
| 4 | TIMP1 | TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820] | 42 | 4.905 | 0.2056 | Yes |
| 5 | CCL4 | C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] | 85 | 4.742 | 0.2539 | Yes |
| 6 | MMP9 | matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] | 111 | 4.590 | 0.3010 | Yes |
| 7 | TNF | tumor necrosis factor [Source:HGNC Symbol;Acc:HGNC:11892] | 116 | 4.554 | 0.3483 | Yes |
| 8 | PDGFB | platelet derived growth factor subunit B [Source:HGNC Symbol;Acc:HGNC:8800] | 122 | 4.520 | 0.3952 | Yes |
| 9 | EDN1 | endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] | 174 | 4.265 | 0.4382 | Yes |
| 10 | CCR3 | C-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:1604] | 294 | 3.816 | 0.4747 | Yes |
| 11 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 322 | 3.713 | 0.5127 | Yes |
| 12 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 351 | 3.623 | 0.5496 | Yes |
| 13 | DSP | desmoplakin [Source:HGNC Symbol;Acc:HGNC:3052] | 411 | 3.420 | 0.5836 | Yes |
| 14 | SPP1 | secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255] | 452 | 3.330 | 0.6172 | Yes |
| 15 | CCR2 | C-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:1603] | 596 | 3.001 | 0.6446 | Yes |
| 16 | MMP2 | matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166] | 610 | 2.974 | 0.6752 | Yes |
| 17 | SKIL | SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897] | 620 | 2.960 | 0.7057 | Yes |
| 18 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 715 | 2.761 | 0.7319 | Yes |
| 19 | SMAD7 | SMAD family member 7 [Source:HGNC Symbol;Acc:HGNC:6773] | 939 | 2.445 | 0.7514 | Yes |
| 20 | HMOX1 | heme oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:5013] | 1275 | 1.977 | 0.7629 | Yes |
| 21 | CEBPB | CCAAT enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834] | 1297 | 1.962 | 0.7828 | Yes |
| 22 | PDGFA | platelet derived growth factor subunit A [Source:HGNC Symbol;Acc:HGNC:8799] | 1334 | 1.916 | 0.8017 | Yes |
| 23 | CCL3 | C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] | 1416 | 1.818 | 0.8185 | Yes |
| 24 | DPP9 | dipeptidyl peptidase 9 [Source:HGNC Symbol;Acc:HGNC:18648] | 1650 | 1.699 | 0.8299 | Yes |
| 25 | MECP2 | methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990] | 2784 | 0.993 | 0.8096 | No |
| 26 | ELMOD2 | ELMO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28111] | 3326 | 0.771 | 0.8030 | No |
| 27 | NFE2L2 | nuclear factor, erythroid 2 like 2 [Source:HGNC Symbol;Acc:HGNC:7782] | 3857 | 0.580 | 0.7947 | No |
| 28 | IGF1 | insulin like growth factor 1 [Source:HGNC Symbol;Acc:HGNC:5464] | 4282 | 0.439 | 0.7879 | No |
| 29 | IL12B | interleukin 12B [Source:HGNC Symbol;Acc:HGNC:5970] | 4749 | 0.300 | 0.7784 | No |
| 30 | CCL11 | C-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10610] | 6185 | 0.000 | 0.7396 | No |
| 31 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8106 | 0.000 | 0.6878 | No |
| 32 | CALCA | calcitonin related polypeptide alpha [Source:HGNC Symbol;Acc:HGNC:1437] | 8633 | 0.000 | 0.6736 | No |
| 33 | FAM13A | family with sequence similarity 13 member A [Source:HGNC Symbol;Acc:HGNC:19367] | 10272 | 0.000 | 0.6294 | No |
| 34 | SFTPA2 | surfactant protein A2 [Source:HGNC Symbol;Acc:HGNC:10799] | 11759 | 0.000 | 0.5892 | No |
| 35 | CMA1 | chymase 1 [Source:HGNC Symbol;Acc:HGNC:2097] | 11768 | 0.000 | 0.5890 | No |
| 36 | SFTPA1 | surfactant protein A1 [Source:HGNC Symbol;Acc:HGNC:10798] | 11772 | 0.000 | 0.5889 | No |
| 37 | TGFA | transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765] | 12332 | 0.000 | 0.5738 | No |
| 38 | IL13 | interleukin 13 [Source:HGNC Symbol;Acc:HGNC:5973] | 13685 | 0.000 | 0.5373 | No |
| 39 | ELN | elastin [Source:HGNC Symbol;Acc:HGNC:3327] | 16308 | 0.000 | 0.4665 | No |
| 40 | HGF | hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893] | 17309 | 0.000 | 0.4395 | No |
| 41 | IL4 | interleukin 4 [Source:HGNC Symbol;Acc:HGNC:6014] | 17681 | 0.000 | 0.4295 | No |
| 42 | IL5 | interleukin 5 [Source:HGNC Symbol;Acc:HGNC:6016] | 17683 | 0.000 | 0.4294 | No |
| 43 | SERPINA1 | serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941] | 17751 | 0.000 | 0.4276 | No |
| 44 | BMP7 | bone morphogenetic protein 7 [Source:HGNC Symbol;Acc:HGNC:1074] | 19080 | 0.000 | 0.3918 | No |
| 45 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 19468 | 0.000 | 0.3813 | No |
| 46 | CXCL2 | C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] | 19480 | 0.000 | 0.3810 | No |
| 47 | CYSLTR2 | cysteinyl leukotriene receptor 2 [Source:HGNC Symbol;Acc:HGNC:18274] | 20027 | 0.000 | 0.3663 | No |
| 48 | PTX3 | pentraxin 3 [Source:HGNC Symbol;Acc:HGNC:9692] | 20086 | 0.000 | 0.3647 | No |
| 49 | SFTPC | surfactant protein C [Source:HGNC Symbol;Acc:HGNC:10802] | 21343 | 0.000 | 0.3308 | No |
| 50 | MUC5B | mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516] | 21490 | 0.000 | 0.3269 | No |
| 51 | CSF2 | colony stimulating factor 2 [Source:HGNC Symbol;Acc:HGNC:2434] | 21576 | 0.000 | 0.3246 | No |
| 52 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 22571 | 0.000 | 0.2977 | No |
| 53 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 22572 | 0.000 | 0.2977 | No |
| 54 | TERT | telomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730] | 25126 | 0.000 | 0.2288 | No |
| 55 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 27840 | 0.000 | 0.1555 | No |
| 56 | CCN2 | cellular communication network factor 2 [Source:HGNC Symbol;Acc:HGNC:2500] | 27873 | 0.000 | 0.1546 | No |
| 57 | FGF7 | fibroblast growth factor 7 [Source:HGNC Symbol;Acc:HGNC:3685] | 28853 | -0.197 | 0.1302 | No |
| 58 | EGF | epidermal growth factor [Source:HGNC Symbol;Acc:HGNC:3229] | 30439 | -0.590 | 0.0936 | No |
| 59 | STN1 | STN1 subunit of CST complex [Source:HGNC Symbol;Acc:HGNC:26200] | 30593 | -0.631 | 0.0960 | No |
| 60 | RTEL1 | regulator of telomere elongation helicase 1 [Source:HGNC Symbol;Acc:HGNC:15888] | 32316 | -1.182 | 0.0618 | No |
| 61 | ATP11A | ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552] | 32377 | -1.207 | 0.0728 | No |
| 62 | PARN | poly(A)-specific ribonuclease [Source:HGNC Symbol;Acc:HGNC:8609] | 33815 | -1.739 | 0.0521 | No |
| 63 | PLAU | plasminogen activator, urokinase [Source:HGNC Symbol;Acc:HGNC:9052] | 36283 | -3.494 | 0.0218 | No |
