Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | ZHAN_MULTIPLE_MYELOMA_PR_UP |
| Enrichment Score (ES) | -0.8471263 |
| Normalized Enrichment Score (NES) | -1.619904 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.017949762 |
| FWER p-Value | 0.294 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | TSR1 | TSR1 ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542] | 1358 | 1.888 | -0.0195 | No |
| 2 | PRR11 | proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] | 4938 | 0.248 | -0.1138 | No |
| 3 | GAGE1 | G antigen 1 [Source:HGNC Symbol;Acc:HGNC:4098] | 18790 | 0.000 | -0.4877 | No |
| 4 | MAGEA1 | MAGE family member A1 [Source:HGNC Symbol;Acc:HGNC:6796] | 23900 | 0.000 | -0.6256 | No |
| 5 | MAGEA3 | MAGE family member A3 [Source:HGNC Symbol;Acc:HGNC:6801] | 23906 | 0.000 | -0.6258 | No |
| 6 | FAM72C | family with sequence similarity 72 member C [Source:HGNC Symbol;Acc:HGNC:30602] | 27247 | 0.000 | -0.7159 | No |
| 7 | SLC19A1 | solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937] | 29079 | -0.253 | -0.7631 | No |
| 8 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7864 | No |
| 9 | MPC2 | mitochondrial pyruvate carrier 2 [Source:HGNC Symbol;Acc:HGNC:24515] | 30636 | -0.642 | -0.7945 | No |
| 10 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31243 | -0.829 | -0.8033 | No |
| 11 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.8177 | No |
| 12 | KPNA2 | karyopherin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:6395] | 32455 | -1.235 | -0.8146 | No |
| 13 | ZWILCH | zwilch kinetochore protein [Source:HGNC Symbol;Acc:HGNC:25468] | 33660 | -1.669 | -0.8319 | Yes |
| 14 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.8285 | Yes |
| 15 | CCNB1 | cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579] | 34381 | -2.017 | -0.8155 | Yes |
| 16 | CENPL | centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879] | 34451 | -2.062 | -0.7986 | Yes |
| 17 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.7834 | Yes |
| 18 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.7675 | Yes |
| 19 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 34811 | -2.286 | -0.7471 | Yes |
| 20 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34864 | -2.323 | -0.7274 | Yes |
| 21 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.7074 | Yes |
| 22 | SPC24 | SPC24 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:26913] | 34922 | -2.364 | -0.6858 | Yes |
| 23 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.6707 | Yes |
| 24 | CCDC34 | coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079] | 35271 | -2.565 | -0.6488 | Yes |
| 25 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35359 | -2.639 | -0.6272 | Yes |
| 26 | TRIP13 | thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307] | 35484 | -2.727 | -0.6057 | Yes |
| 27 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.5835 | Yes |
| 28 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 35644 | -2.897 | -0.5573 | Yes |
| 29 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35697 | -2.900 | -0.5323 | Yes |
| 30 | SKA1 | spindle and kinetochore associated complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28109] | 35917 | -3.089 | -0.5101 | Yes |
| 31 | SPC25 | SPC25 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:24031] | 36011 | -3.197 | -0.4835 | Yes |
| 32 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36034 | -3.229 | -0.4547 | Yes |
| 33 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.4266 | Yes |
| 34 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36132 | -3.332 | -0.3971 | Yes |
| 35 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36250 | -3.453 | -0.3688 | Yes |
| 36 | NUF2 | NUF2 component of NDC80 kinetochore complex [Source:HGNC Symbol;Acc:HGNC:14621] | 36263 | -3.468 | -0.3375 | Yes |
| 37 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.3060 | Yes |
| 38 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.2759 | Yes |
| 39 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36385 | -3.578 | -0.2444 | Yes |
| 40 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.2139 | Yes |
| 41 | NEK2 | NIMA related kinase 2 [Source:HGNC Symbol;Acc:HGNC:7745] | 36597 | -3.856 | -0.1813 | Yes |
| 42 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.1462 | Yes |
| 43 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36761 | -4.065 | -0.1135 | Yes |
| 44 | DEPDC1B | DEP domain containing 1B [Source:HGNC Symbol;Acc:HGNC:24902] | 36832 | -4.186 | -0.0773 | Yes |
| 45 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | -0.0398 | Yes |
| 46 | DSCC1 | DNA replication and sister chromatid cohesion 1 [Source:HGNC Symbol;Acc:HGNC:24453] | 37036 | -4.755 | 0.0015 | Yes |
