Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_LPS |
| GeneSet | GGGNNTTTCC_NFKB_Q6_01 |
| Enrichment Score (ES) | 0.51774967 |
| Normalized Enrichment Score (NES) | 1.334993 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CCL5 | C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] | 5 | 4.992 | 0.0283 | Yes |
| 2 | IL1RN | interleukin 1 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:6000] | 37 | 4.938 | 0.0556 | Yes |
| 3 | TNFRSF1B | TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917] | 45 | 4.889 | 0.0833 | Yes |
| 4 | BCL6B | BCL6B transcription repressor [Source:HGNC Symbol;Acc:HGNC:1002] | 78 | 4.783 | 0.1097 | Yes |
| 5 | CD86 | CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] | 142 | 4.425 | 0.1332 | Yes |
| 6 | CCDC80 | coiled-coil domain containing 80 [Source:HGNC Symbol;Acc:HGNC:30649] | 149 | 4.389 | 0.1581 | Yes |
| 7 | CCND2 | cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583] | 178 | 4.238 | 0.1815 | Yes |
| 8 | BCL3 | BCL3 transcription coactivator [Source:HGNC Symbol;Acc:HGNC:998] | 285 | 3.875 | 0.2007 | Yes |
| 9 | NFKB2 | nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] | 307 | 3.782 | 0.2217 | Yes |
| 10 | TNFSF15 | TNF superfamily member 15 [Source:HGNC Symbol;Acc:HGNC:11931] | 319 | 3.719 | 0.2426 | Yes |
| 11 | MT2A | metallothionein 2A [Source:HGNC Symbol;Acc:HGNC:7406] | 322 | 3.713 | 0.2637 | Yes |
| 12 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 330 | 3.672 | 0.2844 | Yes |
| 13 | IL6 | interleukin 6 [Source:HGNC Symbol;Acc:HGNC:6018] | 351 | 3.623 | 0.3045 | Yes |
| 14 | REL | REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954] | 383 | 3.515 | 0.3237 | Yes |
| 15 | TNIP1 | TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903] | 444 | 3.352 | 0.3412 | Yes |
| 16 | PTGES | prostaglandin E synthase [Source:HGNC Symbol;Acc:HGNC:9599] | 541 | 3.096 | 0.3563 | Yes |
| 17 | EHD1 | EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242] | 562 | 3.090 | 0.3734 | Yes |
| 18 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 784 | 2.619 | 0.3823 | Yes |
| 19 | SH2B3 | SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605] | 931 | 2.459 | 0.3924 | Yes |
| 20 | RAP2C | RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165] | 1067 | 2.239 | 0.4015 | Yes |
| 21 | IPO4 | importin 4 [Source:HGNC Symbol;Acc:HGNC:19426] | 1133 | 2.147 | 0.4120 | Yes |
| 22 | CNIH2 | cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744] | 1146 | 2.130 | 0.4238 | Yes |
| 23 | FHL3 | four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704] | 1418 | 1.817 | 0.4268 | Yes |
| 24 | KY | kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576] | 1470 | 1.802 | 0.4357 | Yes |
| 25 | CSF2RB | colony stimulating factor 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:2436] | 1476 | 1.802 | 0.4458 | Yes |
| 26 | CXCR5 | C-X-C motif chemokine receptor 5 [Source:HGNC Symbol;Acc:HGNC:1060] | 1540 | 1.802 | 0.4544 | Yes |
| 27 | SLAMF8 | SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391] | 1603 | 1.754 | 0.4627 | Yes |
| 28 | RYBP | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | 1633 | 1.724 | 0.4718 | Yes |
| 29 | CPEB4 | cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747] | 1797 | 1.571 | 0.4763 | Yes |
| 30 | IER5 | immediate early response 5 [Source:HGNC Symbol;Acc:HGNC:5393] | 1938 | 1.480 | 0.4809 | Yes |
| 31 | WNT10A | Wnt family member 10A [Source:HGNC Symbol;Acc:HGNC:13829] | 2082 | 1.378 | 0.4849 | Yes |
| 32 | BIRC3 | baculoviral IAP repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:591] | 2131 | 1.335 | 0.4912 | Yes |
| 33 | GATA4 | GATA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:4173] | 2247 | 1.270 | 0.4954 | Yes |
| 34 | LASP1 | LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513] | 2253 | 1.264 | 0.5024 | Yes |
| 35 | ORAI1 | ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] | 2423 | 1.161 | 0.5045 | Yes |
| 36 | ZFAND3 | zinc finger AN1-type containing 3 [Source:HGNC Symbol;Acc:HGNC:18019] | 2530 | 1.129 | 0.5081 | Yes |
| 37 | PFN1 | profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881] | 2635 | 1.069 | 0.5113 | Yes |
| 38 | E2F3 | E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115] | 2897 | 0.945 | 0.5097 | Yes |
| 39 | TPM3 | tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012] | 3037 | 0.878 | 0.5109 | Yes |
| 40 | TNKS1BP1 | tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081] | 3292 | 0.785 | 0.5085 | Yes |
| 41 | RELB | RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] | 3506 | 0.706 | 0.5068 | Yes |
| 42 | MAML2 | mastermind like transcriptional coactivator 2 [Source:HGNC Symbol;Acc:HGNC:16259] | 3517 | 0.702 | 0.5105 | Yes |
| 43 | STAT6 | signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368] | 3576 | 0.679 | 0.5128 | Yes |
| 44 | UBE2M | ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491] | 3631 | 0.658 | 0.5151 | Yes |
| 45 | MYADM | myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544] | 3669 | 0.645 | 0.5177 | Yes |
| 46 | TP53 | tumor protein p53 [Source:HGNC Symbol;Acc:HGNC:11998] | 4925 | 0.253 | 0.4852 | No |
| 47 | UPF2 | UPF2 regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854] | 5013 | 0.225 | 0.4842 | No |
| 48 | ETV1 | ETS variant transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3490] | 5051 | 0.214 | 0.4844 | No |
| 49 | SLC25A18 | solute carrier family 25 member 18 [Source:HGNC Symbol;Acc:HGNC:10988] | 5421 | 0.153 | 0.4753 | No |
| 50 | BMP2K | BMP2 inducible kinase [Source:HGNC Symbol;Acc:HGNC:18041] | 5769 | 0.112 | 0.4665 | No |
| 51 | N4BP1 | NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850] | 6061 | 0.022 | 0.4588 | No |
| 52 | RBMS1 | RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907] | 6064 | 0.022 | 0.4588 | No |
| 53 | GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804] | 6111 | 0.010 | 0.4577 | No |
| 54 | SMPD3 | sphingomyelin phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:14240] | 7901 | 0.000 | 0.4092 | No |
| 55 | GREM1 | gremlin 1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:2001] | 8106 | 0.000 | 0.4037 | No |
| 56 | POU2F3 | POU class 2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:19864] | 8302 | 0.000 | 0.3984 | No |
| 57 | PRR34 | PRR34 long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:25606] | 8742 | 0.000 | 0.3866 | No |
| 58 | MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765] | 9009 | 0.000 | 0.3794 | No |
| 59 | TNFRSF9 | TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] | 9675 | 0.000 | 0.3614 | No |
| 60 | KCNS3 | potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] | 9795 | 0.000 | 0.3582 | No |
| 61 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 10211 | 0.000 | 0.3469 | No |
| 62 | IL1RAPL1 | interleukin 1 receptor accessory protein like 1 [Source:HGNC Symbol;Acc:HGNC:5996] | 10302 | 0.000 | 0.3445 | No |
| 63 | NRIP2 | nuclear receptor interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:23078] | 10729 | 0.000 | 0.3330 | No |
| 64 | NTRK3 | neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033] | 10860 | 0.000 | 0.3294 | No |
| 65 | SP6 | Sp6 transcription factor [Source:HGNC Symbol;Acc:HGNC:14530] | 12268 | 0.000 | 0.2914 | No |
| 66 | MSX1 | msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] | 12386 | 0.000 | 0.2882 | No |
| 67 | UBD | ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] | 12679 | 0.000 | 0.2803 | No |
| 68 | TLX1 | T cell leukemia homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5056] | 14244 | 0.000 | 0.2380 | No |
| 69 | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 16174 | 0.000 | 0.1858 | No |
| 70 | IL2 | interleukin 2 [Source:HGNC Symbol;Acc:HGNC:6001] | 17680 | 0.000 | 0.1451 | No |
| 71 | LPO | lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] | 18675 | 0.000 | 0.1182 | No |
| 72 | MSC | musculin [Source:HGNC Symbol;Acc:HGNC:7321] | 19061 | 0.000 | 0.1078 | No |
| 73 | BNC2 | basonuclin 2 [Source:HGNC Symbol;Acc:HGNC:30988] | 19285 | 0.000 | 0.1017 | No |
| 74 | NR2F2 | nuclear receptor subfamily 2 group F member 2 [Source:HGNC Symbol;Acc:HGNC:7976] | 19583 | 0.000 | 0.0937 | No |
| 75 | CNTF | ciliary neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:2169] | 20091 | 0.000 | 0.0800 | No |
| 76 | C1QL1 | complement C1q like 1 [Source:HGNC Symbol;Acc:HGNC:24182] | 20241 | 0.000 | 0.0759 | No |
| 77 | ENTHD1 | ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352] | 20410 | 0.000 | 0.0714 | No |
| 78 | FOXS1 | forkhead box S1 [Source:HGNC Symbol;Acc:HGNC:3735] | 20455 | 0.000 | 0.0702 | No |
| 79 | LAMA1 | laminin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6481] | 20762 | 0.000 | 0.0619 | No |
| 80 | NRGN | neurogranin [Source:HGNC Symbol;Acc:HGNC:8000] | 21209 | 0.000 | 0.0499 | No |
| 81 | FTHL17 | ferritin heavy chain like 17 [Source:HGNC Symbol;Acc:HGNC:3987] | 21473 | 0.000 | 0.0427 | No |
| 82 | FGF1 | fibroblast growth factor 1 [Source:HGNC Symbol;Acc:HGNC:3665] | 22571 | 0.000 | 0.0131 | No |
| 83 | SOX5 | SRY-box transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:11201] | 23341 | 0.000 | -0.0078 | No |
| 84 | ZNF532 | zinc finger protein 532 [Source:HGNC Symbol;Acc:HGNC:30940] | 26690 | 0.000 | -0.0983 | No |
| 85 | CD70 | CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937] | 27998 | 0.000 | -0.1337 | No |
| 86 | BATF | basic leucine zipper ATF-like transcription factor [Source:HGNC Symbol;Acc:HGNC:958] | 28116 | 0.000 | -0.1369 | No |
| 87 | RSPRY1 | ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420] | 28432 | -0.076 | -0.1450 | No |
| 88 | DCLK1 | doublecortin like kinase 1 [Source:HGNC Symbol;Acc:HGNC:2700] | 28683 | -0.148 | -0.1509 | No |
| 89 | PLXNB1 | plexin B1 [Source:HGNC Symbol;Acc:HGNC:9103] | 28864 | -0.201 | -0.1546 | No |
| 90 | GPR182 | G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] | 28956 | -0.226 | -0.1558 | No |
| 91 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon [Source:HGNC Symbol;Acc:HGNC:9313] | 29147 | -0.274 | -0.1594 | No |
| 92 | FUT7 | fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018] | 29270 | -0.303 | -0.1609 | No |
| 93 | PSME3IP1 | proteasome activator subunit 3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29856] | 29783 | -0.426 | -0.1724 | No |
| 94 | WRAP53 | WD repeat containing antisense to TP53 [Source:HGNC Symbol;Acc:HGNC:25522] | 29939 | -0.465 | -0.1739 | No |
| 95 | G3BP1 | G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292] | 30018 | -0.487 | -0.1733 | No |
| 96 | RPS6KA4 | ribosomal protein S6 kinase A4 [Source:HGNC Symbol;Acc:HGNC:10433] | 30133 | -0.520 | -0.1734 | No |
| 97 | LTB | lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711] | 30277 | -0.561 | -0.1740 | No |
| 98 | UBE2H | ubiquitin conjugating enzyme E2 H [Source:HGNC Symbol;Acc:HGNC:12484] | 30687 | -0.655 | -0.1814 | No |
| 99 | ARID1A | AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110] | 30767 | -0.677 | -0.1797 | No |
| 100 | HIVEP1 | HIVEP zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4920] | 30921 | -0.718 | -0.1797 | No |
| 101 | CREB1 | cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345] | 30973 | -0.734 | -0.1769 | No |
| 102 | JAK3 | Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193] | 31035 | -0.756 | -0.1742 | No |
| 103 | CDC27 | cell division cycle 27 [Source:HGNC Symbol;Acc:HGNC:1728] | 31051 | -0.766 | -0.1703 | No |
| 104 | ENO3 | enolase 3 [Source:HGNC Symbol;Acc:HGNC:3354] | 31109 | -0.787 | -0.1673 | No |
| 105 | CCR10 | C-C motif chemokine receptor 10 [Source:HGNC Symbol;Acc:HGNC:4474] | 31312 | -0.852 | -0.1680 | No |
| 106 | SH3KBP1 | SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867] | 31512 | -0.900 | -0.1682 | No |
| 107 | PKN1 | protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405] | 31743 | -0.974 | -0.1689 | No |
| 108 | SLC12A2 | solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] | 31775 | -0.983 | -0.1641 | No |
| 109 | TCEA2 | transcription elongation factor A2 [Source:HGNC Symbol;Acc:HGNC:11614] | 31809 | -0.993 | -0.1593 | No |
| 110 | STX4 | syntaxin 4 [Source:HGNC Symbol;Acc:HGNC:11439] | 31974 | -1.053 | -0.1578 | No |
| 111 | GEM | GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] | 32498 | -1.249 | -0.1648 | No |
| 112 | RASSF2 | Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883] | 32559 | -1.277 | -0.1592 | No |
| 113 | PNKD | PNKD metallo-beta-lactamase domain containing [Source:HGNC Symbol;Acc:HGNC:9153] | 32610 | -1.291 | -0.1531 | No |
| 114 | CD74 | CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697] | 32684 | -1.319 | -0.1476 | No |
| 115 | CNTNAP1 | contactin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:8011] | 32703 | -1.328 | -0.1405 | No |
| 116 | NFAT5 | nuclear factor of activated T cells 5 [Source:HGNC Symbol;Acc:HGNC:7774] | 32864 | -1.408 | -0.1368 | No |
| 117 | KAT7 | lysine acetyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:17016] | 33369 | -1.535 | -0.1417 | No |
| 118 | CCDC107 | coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465] | 33509 | -1.605 | -0.1363 | No |
| 119 | CHD6 | chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057] | 33550 | -1.622 | -0.1282 | No |
| 120 | CYLD | CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584] | 33572 | -1.634 | -0.1194 | No |
| 121 | TUBA1A | tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] | 33775 | -1.722 | -0.1151 | No |
| 122 | SLC44A1 | solute carrier family 44 member 1 [Source:HGNC Symbol;Acc:HGNC:18798] | 33857 | -1.756 | -0.1072 | No |
| 123 | SLC6A12 | solute carrier family 6 member 12 [Source:HGNC Symbol;Acc:HGNC:11045] | 34580 | -2.138 | -0.1146 | No |
| 124 | ALG6 | ALG6 alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157] | 34694 | -2.210 | -0.1051 | No |
| 125 | S1PR2 | sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169] | 34709 | -2.224 | -0.0928 | No |
| 126 | TOM1L1 | target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983] | 35163 | -2.484 | -0.0909 | No |
| 127 | TRIM47 | tripartite motif containing 47 [Source:HGNC Symbol;Acc:HGNC:19020] | 35354 | -2.629 | -0.0810 | No |
| 128 | LIX1L | limb and CNS expressed 1 like [Source:HGNC Symbol;Acc:HGNC:28715] | 35480 | -2.722 | -0.0689 | No |
| 129 | MIDEAS | mitotic deacetylase associated SANT domain protein [Source:HGNC Symbol;Acc:HGNC:19853] | 35486 | -2.729 | -0.0535 | No |
| 130 | HOXA4 | homeobox A4 [Source:HGNC Symbol;Acc:HGNC:5105] | 35865 | -3.041 | -0.0463 | No |
| 131 | CALCOCO1 | calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306] | 35934 | -3.107 | -0.0305 | No |
| 132 | FAM117A | family with sequence similarity 117 member A [Source:HGNC Symbol;Acc:HGNC:24179] | 36256 | -3.460 | -0.0194 | No |
| 133 | CSF1R | colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433] | 36432 | -3.628 | -0.0035 | No |
| 134 | ENKD1 | enkurin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25246] | 36520 | -3.733 | 0.0154 | No |
