Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_CCNA2 |
| Enrichment Score (ES) | -0.84803045 |
| Normalized Enrichment Score (NES) | -1.7049234 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.2639318E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3147 | 0.848 | -0.0803 | No |
| 2 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 5609 | 0.153 | -0.1459 | No |
| 3 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 15811 | 0.000 | -0.4214 | No |
| 4 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.6253 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.8049 | No |
| 6 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.8357 | No |
| 7 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 31736 | -0.972 | -0.8382 | Yes |
| 8 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 31758 | -0.979 | -0.8333 | Yes |
| 9 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.8377 | Yes |
| 10 | CENPA | centromere protein A [Source:HGNC Symbol;Acc:HGNC:1851] | 32379 | -1.207 | -0.8370 | Yes |
| 11 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 32680 | -1.319 | -0.8378 | Yes |
| 12 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.8306 | Yes |
| 13 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 33128 | -1.519 | -0.8339 | Yes |
| 14 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.8326 | Yes |
| 15 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 33975 | -1.818 | -0.8379 | Yes |
| 16 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.8294 | Yes |
| 17 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.8222 | Yes |
| 18 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 34433 | -2.054 | -0.8175 | Yes |
| 19 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.8104 | Yes |
| 20 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.8025 | Yes |
| 21 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 34811 | -2.286 | -0.7901 | Yes |
| 22 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.7774 | Yes |
| 23 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34864 | -2.323 | -0.7656 | Yes |
| 24 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.7539 | Yes |
| 25 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.7441 | Yes |
| 26 | KIF20A | kinesin family member 20A [Source:HGNC Symbol;Acc:HGNC:9787] | 35171 | -2.487 | -0.7333 | Yes |
| 27 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.7203 | Yes |
| 28 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527] | 35359 | -2.639 | -0.7094 | Yes |
| 29 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 35517 | -2.758 | -0.6982 | Yes |
| 30 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35524 | -2.765 | -0.6829 | Yes |
| 31 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.6680 | Yes |
| 32 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35620 | -2.871 | -0.6537 | Yes |
| 33 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.6377 | Yes |
| 34 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.6218 | Yes |
| 35 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35697 | -2.900 | -0.6072 | Yes |
| 36 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35789 | -2.981 | -0.5930 | Yes |
| 37 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35792 | -2.983 | -0.5763 | Yes |
| 38 | CDCA3 | cell division cycle associated 3 [Source:HGNC Symbol;Acc:HGNC:14624] | 35805 | -2.996 | -0.5599 | Yes |
| 39 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.5432 | Yes |
| 40 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35818 | -3.002 | -0.5266 | Yes |
| 41 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35839 | -3.018 | -0.5102 | Yes |
| 42 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35936 | -3.111 | -0.4954 | Yes |
| 43 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35969 | -3.152 | -0.4787 | Yes |
| 44 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36017 | -3.205 | -0.4620 | Yes |
| 45 | NCAPG | non-SMC condensin I complex subunit G [Source:HGNC Symbol;Acc:HGNC:24304] | 36020 | -3.209 | -0.4441 | Yes |
| 46 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36034 | -3.229 | -0.4264 | Yes |
| 47 | KIF4A | kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339] | 36087 | -3.264 | -0.4095 | Yes |
| 48 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.3915 | Yes |
| 49 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36132 | -3.332 | -0.3736 | Yes |
| 50 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36135 | -3.335 | -0.3550 | Yes |
| 51 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.3379 | Yes |
| 52 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36250 | -3.453 | -0.3196 | Yes |
| 53 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.3006 | Yes |
| 54 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36308 | -3.499 | -0.2821 | Yes |
| 55 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.2625 | Yes |
| 56 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.2437 | Yes |
| 57 | E2F8 | E2F transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:24727] | 36385 | -3.578 | -0.2247 | Yes |
| 58 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.2071 | Yes |
| 59 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.1864 | Yes |
| 60 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36542 | -3.776 | -0.1663 | Yes |
| 61 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36567 | -3.812 | -0.1456 | Yes |
| 62 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.1245 | Yes |
| 63 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.1034 | Yes |
| 64 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36625 | -3.903 | -0.0822 | Yes |
| 65 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36726 | -4.014 | -0.0624 | Yes |
| 66 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36761 | -4.065 | -0.0406 | Yes |
| 67 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36884 | -4.334 | -0.0196 | Yes |
| 68 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | 0.0035 | Yes |
