Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_MCM4 |
| Enrichment Score (ES) | -0.8424764 |
| Normalized Enrichment Score (NES) | -1.634222 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.001702153 |
| FWER p-Value | 0.021 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3147 | 0.848 | -0.0785 | No |
| 2 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 3331 | 0.769 | -0.0775 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.6183 | No |
| 4 | TCP1 | t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655] | 29475 | -0.354 | -0.7806 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7940 | No |
| 6 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 31304 | -0.852 | -0.8195 | No |
| 7 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.8165 | No |
| 8 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 31736 | -0.972 | -0.8170 | No |
| 9 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 32680 | -1.319 | -0.8324 | Yes |
| 10 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.8225 | Yes |
| 11 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33093 | -1.504 | -0.8219 | Yes |
| 12 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 33128 | -1.519 | -0.8112 | Yes |
| 13 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.8067 | Yes |
| 14 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 33683 | -1.683 | -0.8013 | Yes |
| 15 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.7969 | Yes |
| 16 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.7858 | Yes |
| 17 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 34433 | -2.054 | -0.7769 | Yes |
| 18 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.7654 | Yes |
| 19 | NASP | nuclear autoantigenic sperm protein [Source:HGNC Symbol;Acc:HGNC:7644] | 34638 | -2.171 | -0.7493 | Yes |
| 20 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.7361 | Yes |
| 21 | POLD1 | DNA polymerase delta 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9175] | 34800 | -2.282 | -0.7187 | Yes |
| 22 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.7017 | Yes |
| 23 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34864 | -2.323 | -0.6851 | Yes |
| 24 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.6686 | Yes |
| 25 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34947 | -2.382 | -0.6510 | Yes |
| 26 | HELLS | helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861] | 35106 | -2.423 | -0.6368 | Yes |
| 27 | MAD2L1 | mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763] | 35187 | -2.501 | -0.6198 | Yes |
| 28 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.6012 | Yes |
| 29 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35524 | -2.765 | -0.5883 | Yes |
| 30 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.5677 | Yes |
| 31 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.5476 | Yes |
| 32 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.5258 | Yes |
| 33 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35792 | -2.983 | -0.5072 | Yes |
| 34 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.4847 | Yes |
| 35 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 35888 | -3.059 | -0.4634 | Yes |
| 36 | ASF1B | anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996] | 35936 | -3.111 | -0.4408 | Yes |
| 37 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36017 | -3.205 | -0.4185 | Yes |
| 38 | KIF14 | kinesin family member 14 [Source:HGNC Symbol;Acc:HGNC:19181] | 36034 | -3.229 | -0.3942 | Yes |
| 39 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.3709 | Yes |
| 40 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36132 | -3.332 | -0.3462 | Yes |
| 41 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36135 | -3.335 | -0.3207 | Yes |
| 42 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.2966 | Yes |
| 43 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36308 | -3.499 | -0.2725 | Yes |
| 44 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.2457 | Yes |
| 45 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36332 | -3.523 | -0.2193 | Yes |
| 46 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.1926 | Yes |
| 47 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.1685 | Yes |
| 48 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36542 | -3.776 | -0.1407 | Yes |
| 49 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.1124 | Yes |
| 50 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36625 | -3.903 | -0.0837 | Yes |
| 51 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36726 | -4.014 | -0.0557 | Yes |
| 52 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36761 | -4.065 | -0.0255 | Yes |
| 53 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | 0.0035 | Yes |
