Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_PCNA |
| Enrichment Score (ES) | -0.8371813 |
| Normalized Enrichment Score (NES) | -1.7046126 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.8111455E-4 |
| FWER p-Value | 0.001 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3147 | 0.848 | -0.0801 | No |
| 2 | PA2G4 | proliferation-associated 2G4 [Source:HGNC Symbol;Acc:HGNC:8550] | 3331 | 0.769 | -0.0807 | No |
| 3 | HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:HGNC:5034] | 3337 | 0.767 | -0.0764 | No |
| 4 | MT1JP | metallothionein 1J, pseudogene [Source:HGNC Symbol;Acc:HGNC:7402] | 15811 | 0.000 | -0.4133 | No |
| 5 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.6172 | No |
| 6 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7967 | No |
| 7 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.8274 | No |
| 8 | HMGB2 | high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000] | 31758 | -0.979 | -0.8304 | Yes |
| 9 | VRK1 | VRK serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:12718] | 31834 | -1.006 | -0.8266 | Yes |
| 10 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31894 | -1.023 | -0.8224 | Yes |
| 11 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.8230 | Yes |
| 12 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 32680 | -1.319 | -0.8296 | Yes |
| 13 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.8223 | Yes |
| 14 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 33128 | -1.519 | -0.8254 | Yes |
| 15 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.8239 | Yes |
| 16 | MCM5 | minichromosome maintenance complex component 5 [Source:HGNC Symbol;Acc:HGNC:6948] | 33683 | -1.683 | -0.8218 | Yes |
| 17 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.8209 | Yes |
| 18 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.8135 | Yes |
| 19 | PAXIP1 | PAX interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:8624] | 34188 | -1.925 | -0.8027 | Yes |
| 20 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34248 | -1.957 | -0.7931 | Yes |
| 21 | NSD2 | nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766] | 34280 | -1.977 | -0.7826 | Yes |
| 22 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 34433 | -2.054 | -0.7749 | Yes |
| 23 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.7675 | Yes |
| 24 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.7593 | Yes |
| 25 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 34811 | -2.286 | -0.7465 | Yes |
| 26 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.7336 | Yes |
| 27 | POLE2 | DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178] | 34863 | -2.322 | -0.7215 | Yes |
| 28 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34864 | -2.323 | -0.7082 | Yes |
| 29 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34947 | -2.382 | -0.6967 | Yes |
| 30 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.6859 | Yes |
| 31 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35189 | -2.503 | -0.6752 | Yes |
| 32 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.6614 | Yes |
| 33 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35524 | -2.765 | -0.6538 | Yes |
| 34 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.6385 | Yes |
| 35 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35620 | -2.871 | -0.6239 | Yes |
| 36 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.6075 | Yes |
| 37 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.5912 | Yes |
| 38 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35697 | -2.900 | -0.5762 | Yes |
| 39 | SHCBP1 | SHC binding and spindle associated 1 [Source:HGNC Symbol;Acc:HGNC:29547] | 35789 | -2.981 | -0.5616 | Yes |
| 40 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35792 | -2.983 | -0.5446 | Yes |
| 41 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.5278 | Yes |
| 42 | TMPO | thymopoietin [Source:HGNC Symbol;Acc:HGNC:11875] | 35818 | -3.002 | -0.5108 | Yes |
| 43 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35839 | -3.018 | -0.4941 | Yes |
| 44 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123] | 35848 | -3.029 | -0.4770 | Yes |
| 45 | DTL | denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288] | 35985 | -3.169 | -0.4625 | Yes |
| 46 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36017 | -3.205 | -0.4449 | Yes |
| 47 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.4284 | Yes |
| 48 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36132 | -3.332 | -0.4101 | Yes |
| 49 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.3926 | Yes |
| 50 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36250 | -3.453 | -0.3739 | Yes |
| 51 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.3544 | Yes |
| 52 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36308 | -3.499 | -0.3354 | Yes |
| 53 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.3154 | Yes |
| 54 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.2960 | Yes |
| 55 | KIF15 | kinesin family member 15 [Source:HGNC Symbol;Acc:HGNC:17273] | 36462 | -3.668 | -0.2782 | Yes |
| 56 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.2580 | Yes |
| 57 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.2368 | Yes |
| 58 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36542 | -3.776 | -0.2162 | Yes |
| 59 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36567 | -3.812 | -0.1950 | Yes |
| 60 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.1734 | Yes |
| 61 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.1518 | Yes |
| 62 | MYBL2 | MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548] | 36607 | -3.868 | -0.1298 | Yes |
| 63 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36625 | -3.903 | -0.1079 | Yes |
| 64 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36726 | -4.014 | -0.0876 | Yes |
| 65 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36761 | -4.065 | -0.0652 | Yes |
| 66 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36776 | -4.085 | -0.0422 | Yes |
| 67 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36884 | -4.334 | -0.0202 | Yes |
| 68 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | 0.0035 | Yes |
