Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_RFC4 |
| Enrichment Score (ES) | -0.80505764 |
| Normalized Enrichment Score (NES) | -1.6011205 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0041276915 |
| FWER p-Value | 0.073 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | RANBP1 | RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847] | 3009 | 0.892 | -0.0738 | No |
| 2 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3147 | 0.848 | -0.0704 | No |
| 3 | TIMELESS | timeless circadian regulator [Source:HGNC Symbol;Acc:HGNC:11813] | 4802 | 0.285 | -0.1127 | No |
| 4 | SNRPE | small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:HGNC:11161] | 4887 | 0.264 | -0.1128 | No |
| 5 | DKC1 | dyskerin pseudouridine synthase 1 [Source:HGNC Symbol;Acc:HGNC:2890] | 5054 | 0.214 | -0.1155 | No |
| 6 | RAN | RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846] | 5964 | 0.052 | -0.1396 | No |
| 7 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.6093 | No |
| 8 | CCT2 | chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615] | 28449 | -0.080 | -0.7461 | No |
| 9 | SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide [Source:HGNC Symbol;Acc:HGNC:11158] | 28731 | -0.161 | -0.7523 | No |
| 10 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7854 | No |
| 11 | SSRP1 | structure specific recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:11327] | 30178 | -0.534 | -0.7826 | No |
| 12 | KNTC1 | kinetochore associated 1 [Source:HGNC Symbol;Acc:HGNC:17255] | 30394 | -0.578 | -0.7835 | No |
| 13 | RPA3 | replication protein A3 [Source:HGNC Symbol;Acc:HGNC:10291] | 31192 | -0.813 | -0.7983 | Yes |
| 14 | MCM10 | minichromosome maintenance 10 replication initiation factor [Source:HGNC Symbol;Acc:HGNC:18043] | 31243 | -0.829 | -0.7927 | Yes |
| 15 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit [Source:HGNC Symbol;Acc:HGNC:11465] | 31396 | -0.859 | -0.7896 | Yes |
| 16 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.7835 | Yes |
| 17 | RFC3 | replication factor C subunit 3 [Source:HGNC Symbol;Acc:HGNC:9971] | 31736 | -0.972 | -0.7833 | Yes |
| 18 | SLBP | stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904] | 31894 | -1.023 | -0.7790 | Yes |
| 19 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.7767 | Yes |
| 20 | RFC5 | replication factor C subunit 5 [Source:HGNC Symbol;Acc:HGNC:9973] | 32621 | -1.296 | -0.7785 | Yes |
| 21 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 32680 | -1.319 | -0.7690 | Yes |
| 22 | MLH1 | mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] | 32682 | -1.319 | -0.7581 | Yes |
| 23 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.7472 | Yes |
| 24 | H2AZ1 | H2A.Z variant histone 1 [Source:HGNC Symbol;Acc:HGNC:4741] | 33060 | -1.492 | -0.7447 | Yes |
| 25 | RAD51AP1 | RAD51 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16956] | 33128 | -1.519 | -0.7338 | Yes |
| 26 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.7282 | Yes |
| 27 | CTPS1 | CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] | 33464 | -1.583 | -0.7166 | Yes |
| 28 | CKS1B | CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083] | 33975 | -1.818 | -0.7152 | Yes |
| 29 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.7016 | Yes |
| 30 | PCLAF | PCNA clamp associated factor [Source:HGNC Symbol;Acc:HGNC:28961] | 34181 | -1.920 | -0.6892 | Yes |
| 31 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34248 | -1.957 | -0.6746 | Yes |
| 32 | ITGB3BP | integrin subunit beta 3 binding protein [Source:HGNC Symbol;Acc:HGNC:6157] | 34343 | -2.014 | -0.6603 | Yes |
| 33 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 34433 | -2.054 | -0.6456 | Yes |
| 34 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.6363 | Yes |
| 35 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.6178 | Yes |
| 36 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34864 | -2.323 | -0.5996 | Yes |
| 37 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.5814 | Yes |
| 38 | GINS1 | GINS complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28980] | 34947 | -2.382 | -0.5621 | Yes |
| 39 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.5450 | Yes |
| 40 | RAD54L | RAD54 like [Source:HGNC Symbol;Acc:HGNC:9826] | 35189 | -2.503 | -0.5277 | Yes |
| 41 | NCAPD2 | non-SMC condensin I complex subunit D2 [Source:HGNC Symbol;Acc:HGNC:24305] | 35517 | -2.758 | -0.5135 | Yes |
| 42 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35524 | -2.765 | -0.4906 | Yes |
| 43 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.4680 | Yes |
| 44 | PRIM1 | DNA primase subunit 1 [Source:HGNC Symbol;Acc:HGNC:9369] | 35620 | -2.871 | -0.4458 | Yes |
| 45 | MCM7 | minichromosome maintenance complex component 7 [Source:HGNC Symbol;Acc:HGNC:6950] | 35624 | -2.879 | -0.4218 | Yes |
| 46 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.3980 | Yes |
| 47 | LIG1 | DNA ligase 1 [Source:HGNC Symbol;Acc:HGNC:6598] | 35783 | -2.979 | -0.3771 | Yes |
| 48 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [Source:HGNC Symbol;Acc:HGNC:8587] | 35888 | -3.059 | -0.3543 | Yes |
| 49 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.3326 | Yes |
| 50 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.3070 | Yes |
| 51 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36250 | -3.453 | -0.2792 | Yes |
| 52 | MSH6 | mutS homolog 6 [Source:HGNC Symbol;Acc:HGNC:7329] | 36465 | -3.675 | -0.2542 | Yes |
| 53 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.2243 | Yes |
| 54 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.1944 | Yes |
| 55 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36625 | -3.903 | -0.1630 | Yes |
| 56 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36726 | -4.014 | -0.1321 | Yes |
| 57 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36761 | -4.065 | -0.0991 | Yes |
| 58 | MSH2 | mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325] | 36776 | -4.085 | -0.0654 | Yes |
| 59 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36884 | -4.334 | -0.0320 | Yes |
| 60 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | 0.0035 | Yes |
