Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_RRM2 |
| Enrichment Score (ES) | -0.8555712 |
| Normalized Enrichment Score (NES) | -1.6051913 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0036291266 |
| FWER p-Value | 0.061 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.6305 | No |
| 2 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.8082 | No |
| 3 | CENPM | centromere protein M [Source:HGNC Symbol;Acc:HGNC:18352] | 31304 | -0.852 | -0.8326 | No |
| 4 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.8285 | No |
| 5 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.8378 | No |
| 6 | SMC1A | structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111] | 32814 | -1.377 | -0.8433 | Yes |
| 7 | LMNB1 | lamin B1 [Source:HGNC Symbol;Acc:HGNC:6637] | 33093 | -1.504 | -0.8373 | Yes |
| 8 | MCM3 | minichromosome maintenance complex component 3 [Source:HGNC Symbol;Acc:HGNC:6945] | 33403 | -1.555 | -0.8318 | Yes |
| 9 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.8326 | Yes |
| 10 | MCM6 | minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949] | 34433 | -2.054 | -0.8246 | Yes |
| 11 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.8103 | Yes |
| 12 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.7952 | Yes |
| 13 | UBE2C | ubiquitin conjugating enzyme E2 C [Source:HGNC Symbol;Acc:HGNC:15937] | 34921 | -2.364 | -0.7769 | Yes |
| 14 | AURKA | aurora kinase A [Source:HGNC Symbol;Acc:HGNC:11393] | 35217 | -2.531 | -0.7623 | Yes |
| 15 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.7463 | Yes |
| 16 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.7227 | Yes |
| 17 | DLGAP5 | DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864] | 35697 | -2.900 | -0.6985 | Yes |
| 18 | CDCA8 | cell division cycle associated 8 [Source:HGNC Symbol;Acc:HGNC:14629] | 35792 | -2.983 | -0.6743 | Yes |
| 19 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.6480 | Yes |
| 20 | CENPE | centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856] | 35839 | -3.018 | -0.6218 | Yes |
| 21 | PLK1 | polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077] | 35969 | -3.152 | -0.5972 | Yes |
| 22 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36017 | -3.205 | -0.5698 | Yes |
| 23 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.5427 | Yes |
| 24 | AURKB | aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390] | 36135 | -3.335 | -0.5138 | Yes |
| 25 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.4853 | Yes |
| 26 | BIRC5 | baculoviral IAP repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:593] | 36250 | -3.453 | -0.4555 | Yes |
| 27 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36308 | -3.499 | -0.4258 | Yes |
| 28 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.3945 | Yes |
| 29 | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1148] | 36332 | -3.523 | -0.3636 | Yes |
| 30 | RRM2 | ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452] | 36345 | -3.537 | -0.3324 | Yes |
| 31 | MKI67 | marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107] | 36500 | -3.700 | -0.3035 | Yes |
| 32 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.2705 | Yes |
| 33 | ESPL1 | extra spindle pole bodies like 1, separase [Source:HGNC Symbol;Acc:HGNC:16856] | 36542 | -3.776 | -0.2378 | Yes |
| 34 | H2AX | H2A.X variant histone [Source:HGNC Symbol;Acc:HGNC:4739] | 36567 | -3.812 | -0.2044 | Yes |
| 35 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.1705 | Yes |
| 36 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.1365 | Yes |
| 37 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36625 | -3.903 | -0.1023 | Yes |
| 38 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36726 | -4.014 | -0.0691 | Yes |
| 39 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36884 | -4.334 | -0.0346 | Yes |
| 40 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | 0.0035 | Yes |
