Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | greenberg_collapsed_to_symbols.Nof1.cls #WT_LPS_versus_WT_NA.Nof1.cls #WT_LPS_versus_WT_NA_repos |
| Phenotype | Nof1.cls#WT_LPS_versus_WT_NA_repos |
| Upregulated in class | WT_NA |
| GeneSet | GNF2_TTK |
| Enrichment Score (ES) | -0.8535735 |
| Normalized Enrichment Score (NES) | -1.5915266 |
| Nominal p-value | 0.0013227513 |
| FDR q-value | 0.0054009086 |
| FWER p-Value | 0.105 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | CKS2 | CDC28 protein kinase regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:2000] | 3147 | 0.848 | -0.0765 | No |
| 2 | HJURP | Holliday junction recognition protein [Source:HGNC Symbol;Acc:HGNC:25444] | 5609 | 0.153 | -0.1414 | No |
| 3 | ZWINT | ZW10 interacting kinetochore protein [Source:HGNC Symbol;Acc:HGNC:13195] | 23360 | 0.000 | -0.6204 | No |
| 4 | CCT2 | chaperonin containing TCP1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:1615] | 28449 | -0.080 | -0.7570 | No |
| 5 | TYMS | thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441] | 30117 | -0.515 | -0.7968 | No |
| 6 | PCNA | proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729] | 31440 | -0.872 | -0.8238 | No |
| 7 | CDK1 | cyclin dependent kinase 1 [Source:HGNC Symbol;Acc:HGNC:1722] | 32153 | -1.113 | -0.8320 | No |
| 8 | GINS2 | GINS complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24575] | 32680 | -1.319 | -0.8331 | No |
| 9 | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 32691 | -1.323 | -0.8202 | No |
| 10 | DBF4 | DBF4 zinc finger [Source:HGNC Symbol;Acc:HGNC:17364] | 33929 | -1.793 | -0.8357 | Yes |
| 11 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 34046 | -1.854 | -0.8204 | Yes |
| 12 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 34248 | -1.957 | -0.8064 | Yes |
| 13 | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149] | 34617 | -2.156 | -0.7949 | Yes |
| 14 | FANCI | FA complementation group I [Source:HGNC Symbol;Acc:HGNC:25568] | 34796 | -2.278 | -0.7770 | Yes |
| 15 | TPX2 | TPX2 microtubule nucleation factor [Source:HGNC Symbol;Acc:HGNC:1249] | 34811 | -2.286 | -0.7547 | Yes |
| 16 | MCM2 | minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944] | 34817 | -2.289 | -0.7320 | Yes |
| 17 | RFC4 | replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972] | 34864 | -2.323 | -0.7102 | Yes |
| 18 | SMC2 | structural maintenance of chromosomes 2 [Source:HGNC Symbol;Acc:HGNC:14011] | 35054 | -2.393 | -0.6915 | Yes |
| 19 | SMC4 | structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013] | 35524 | -2.765 | -0.6767 | Yes |
| 20 | RRM1 | ribonucleotide reductase catalytic subunit M1 [Source:HGNC Symbol;Acc:HGNC:10451] | 35552 | -2.794 | -0.6496 | Yes |
| 21 | TOP2A | DNA topoisomerase II alpha [Source:HGNC Symbol;Acc:HGNC:11989] | 35635 | -2.889 | -0.6231 | Yes |
| 22 | CDC20 | cell division cycle 20 [Source:HGNC Symbol;Acc:HGNC:1723] | 35809 | -2.998 | -0.5979 | Yes |
| 23 | MELK | maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870] | 36017 | -3.205 | -0.5716 | Yes |
| 24 | CCNB2 | cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580] | 36104 | -3.290 | -0.5412 | Yes |
| 25 | RACGAP1 | Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804] | 36132 | -3.332 | -0.5088 | Yes |
| 26 | KIF11 | kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388] | 36211 | -3.412 | -0.4770 | Yes |
| 27 | PRC1 | protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341] | 36268 | -3.475 | -0.4439 | Yes |
| 28 | KIF18B | kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102] | 36308 | -3.499 | -0.4102 | Yes |
| 29 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 36309 | -3.500 | -0.3754 | Yes |
| 30 | FOXM1 | forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818] | 36503 | -3.702 | -0.3438 | Yes |
| 31 | CENPU | centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348] | 36525 | -3.754 | -0.3070 | Yes |
| 32 | CCNA2 | cyclin A2 [Source:HGNC Symbol;Acc:HGNC:1578] | 36580 | -3.830 | -0.2704 | Yes |
| 33 | NUSAP1 | nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538] | 36602 | -3.862 | -0.2325 | Yes |
| 34 | KIF2C | kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393] | 36610 | -3.875 | -0.1942 | Yes |
| 35 | GMNN | geminin DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:17493] | 36625 | -3.903 | -0.1557 | Yes |
| 36 | NDC80 | NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909] | 36726 | -4.014 | -0.1185 | Yes |
| 37 | TTK | TTK protein kinase [Source:HGNC Symbol;Acc:HGNC:12401] | 36761 | -4.065 | -0.0790 | Yes |
| 38 | CENPF | centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857] | 36884 | -4.334 | -0.0392 | Yes |
| 39 | ASPM | assembly factor for spindle microtubules [Source:HGNC Symbol;Acc:HGNC:19048] | 36959 | -4.497 | 0.0035 | Yes |
